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Ocular Manifestations

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Aspects of Lyme Borreliosis

Abstract

In Lyme borreliosis, the eye may be involved primarily by inflammation of ocular tissues or secondarily by extraocular manifestations. While ocular symptoms due to conjunctivitis or paresis of the cranial nerves are frequent, intraocular inflammations caused by Borrelia burgdorferi seem to be rare and are difficult to diagnose.

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References

  • Aaberg TM (1989) The expanding ophthalmologic spectrum of Lyme disease. Am J Ophthalmol 107:77–80

    PubMed  CAS  Google Scholar 

  • Ackermann R, Rehse-Küper B, Gollmer E, Schmidt R (1988) Chronic neurologic manifestations of erythema migrans borreliosis. Ann N Y Acad Sci 539:16–23

    Article  PubMed  CAS  Google Scholar 

  • Asbrink E, Hovmark A, Olsson I (1989) Borrelial lymphocytoma in Sweden. Zentral Bakteriol (Suppl) 18:156–163

    Google Scholar 

  • Baum J, Barzal M (1989) The expanding ophthalmologic spectrum of Lyme disease. Am J Ophthalmol 107:684–685

    PubMed  CAS  Google Scholar 

  • Baum J, Barza M, Weinstein P, Groden J, Aswad M (1988) Bilateral keratitis as a manifestation of Lyme disease. Am J Ophthal 105:75–77

    PubMed  CAS  Google Scholar 

  • Bertuch AW, Rocco E, Schwartz EG (1988) Lyme disease: ocular manifestations. Ann Ophthalmol 20:376–378

    PubMed  CAS  Google Scholar 

  • Bialasiewicz AA, Schönherr U (1990), Choriokapillaritis (sog. Pigmentepitheliitis) bei Borrelia burgdorferi-Serokonversion. Klin Monatsbl Augenheilkd 196:481–483

    Article  PubMed  CAS  Google Scholar 

  • Bialasiewicz AA, Ruprecht KW, Naumann GOH, Blenk H (1988) Bilateral diffuse chorioditis and exsudative retinal detachments with evidence of Lyme disease (letter) Am J Ophthalmol 105:419–420

    Article  PubMed  CAS  Google Scholar 

  • Bialasiewicz AA, Huk W, Druschky KF, Naumann GOH (1989) Borrelia burgdorferi-lniokiion mit beidseitiger Neuritis nervi optici und intrazerebralen Demyelinisierungsherden. Klin Monatsbl Augenheilkd 195:91–94

    Article  PubMed  CAS  Google Scholar 

  • Boutros A, Rahn E, Nauheim R (1990) Iritis and papillitis as a primary presentation of Lyme disease. Ann Ophthalmol 22:24–25

    PubMed  CAS  Google Scholar 

  • Duke-Elder S (1976) System of ophthalmology, vol XV. Kimpton, London pp 150–155

    Google Scholar 

  • Duray PH, Johnson RC (1986) The histopathology of experimentally infected hamsters with the Lyme disease spirochete, Borrelia burgdorferi. Proc Soc Exp Biol Med 181:263–269

    PubMed  CAS  Google Scholar 

  • Eichenfield AH, Goldsmith DP, Benach JL et al. (1986) Childhood Lyme arthritis: experience in an endemic area. J Pediatr 109:753–758

    Article  PubMed  CAS  Google Scholar 

  • Farris BK, Webb RM (1988) Lyme disease and optic neuritis. J Clin Neuro Ophthalmol 8:73–78

    Google Scholar 

  • Fraunfelder FT (1990) Lyme disease. In: Fraunfelder FT, Roy FH (eds) Current ocular therapy, Vol 3. J Clin Neuro Ophthalmol 9:225–228

    Google Scholar 

  • Glauser TA, Brennant PJ, Galetta SL (1989) Reversible Horner’s syndrome and Lyme disease. J Clin Neuro Ophthalmol 9:225–228

    CAS  Google Scholar 

  • Hänny PE, Häuselmann HJ (1987) Die Lyme-Krankheit aus der Sicht des Neurologen. Schweiz Med Wochenschr 117:901–915

    PubMed  Google Scholar 

  • Jacobs JC, Stevens M, Durray PH (1986) Lyme disease simulating septic arthritis. JAMA 256:1138–1139

    Article  PubMed  CAS  Google Scholar 

  • Jacobsen DM, Frens DB (1989) Pseudotumor cerebri syndrome associated with Lyme disease. Am J Ophthalmol 107:81–82

    Google Scholar 

  • Johnson RC, Marek N, Kodner C (1984) Infection of Syrian hamsters with Lyme disease spirochetes. J Clin Microbiol 20:1099–1101

    PubMed  CAS  Google Scholar 

  • Kauffmann DJH, Wormser GP (1990) Ocular Lyme disease: case report and review of the literature. Br J Ophthalmol 74:325–327

    Article  PubMed  CAS  Google Scholar 

  • Kehl F, Aust W (1988) Augenbefunde bei Zecken-Borreliose. Klin Monatsbl Augenheilkd 193:66–68

    Article  PubMed  CAS  Google Scholar 

  • Kornmehl EW, Lesser RL, Jaros P, Rocco E, Steere AC (1989) Bilateral keratitis in Lyme disease. Ophthalmology 96:1194–1197

    PubMed  CAS  Google Scholar 

  • Krause A, Schönherr U, Schörner C, Brade V, Burmester RG (1991) Gonarthritis, Lymphadeno- pathie und disseminierte Chorioditis als primäre Manifestation einer Lyme-Borreliose. Kasuistik und Diskussion der diagnostischen Möglichkeiten bei der Lyme-Borreliose. Z Rheumatol 50:10–15

    PubMed  CAS  Google Scholar 

  • Kuiper H, Koelman JHTM, Jager MJ (1989) Vitreous clouding associated with Lyme borreliosis. Am J Ophthalmol 108:453–454

    PubMed  CAS  Google Scholar 

  • Lang GE, Schönherr U, Naumann GOH (1991) Retinal vasculitis with proliferative retinopathy in a patient with evidence of Borrelia burgdorferi infection. Am J Ophthalmol 111:243–244

    PubMed  CAS  Google Scholar 

  • Lesser RL, Kornmehl EW, Pachner AR (1990) Neuro-ophthalmologic manifestations of Lyme disease. Ophthalmology 97:699–706

    PubMed  CAS  Google Scholar 

  • Maonald AB (1987) Lyme disease, a neuro-ophthalmologic view. J Clin Neuro Ophthalmol 7:185–190

    Google Scholar 

  • May EF, Jabbari B (1990) Stroke in neuroborreliosis. Stroke 21:1232–1235

    Article  PubMed  CAS  Google Scholar 

  • Naumann GOH, Apple DJ (1986) Optic nerve. In: Naumann GOH, Apple DJ (eds) Pathology of the eye. Springer, Berlin Heidelberg New York, pp 723–770

    Chapter  Google Scholar 

  • Naumann GOH, Naumann LR (1986) Intraocular inflammation. In: Naumann GOH, Apple DJ (eds) Pathology of the eye. Springer, Berlin Heidelberg New York pp 99–184

    Chapter  Google Scholar 

  • Orlin SE, Lauffer JL (1989) Lyme disease keratitis. Am J Ophthalmol 107:678–680

    PubMed  CAS  Google Scholar 

  • Pfister HW, Einhaupl KM, Wilske B, Preac-Mursic V (1986) Bannwarth’s syndrome and the enlarged neurological spectrum of anthropod borne borreliosis. Zentralbl Bakteriol Hyg (A) 263:343–347

    Google Scholar 

  • Pizzarello LD, MacDonald AB, Semlear R, DiLeo F, Berger B (1989) Temporal arteritits associated with Borrelia infection. A case report. J Clin Neuro Ophthalmol 9:3

    Article  CAS  Google Scholar 

  • Raucher HS, Kaufman DM, Goldfarb J, Jacobson RI, Roseman B, Wolff RR (1985) Pseudotumor cerebri and Lyme disease, a new association. J Pediatr 107:931

    Article  PubMed  CAS  Google Scholar 

  • Reik L, Steere AC, Bartenhagen NH, Shope RE, Malawista SE (1979) Neurologic abnormalities of Lyme disease. Medicine (Baltimore) 58:281–294

    CAS  Google Scholar 

  • Reik L, Burgdorfer W, Donaldson JO (1986) Neurologic abnormalities of Lyme disease without erythema chronicum migrans. Am J Med 81:73–78

    Article  PubMed  Google Scholar 

  • Schlechter SL (1986) Lyme disease associated with optic neuropathy. Am J Med 81:143–145

    Article  Google Scholar 

  • Schmidt R, Ackermann R (1985) Durch Zecken übertragene Meningo-Polyneuritis (Garin-Buja- doux-Bannwarth) - Erythema chronicum migrans-Krankheit des Nervensystems. Fortschr Neurol Psychiatr 53:145–153

    Article  PubMed  CAS  Google Scholar 

  • Schönherr U, Wilk CM, Lang GE, Naumann GOH (1990) IgM Borrelia burgdorferi antibody titers in patients with ocular manifestations of Lyme borreliosis. Invest Ophthalmol Vis Sci 31:2804

    Google Scholar 

  • Schönherr U, Lang GE, Meythaler FH (1991) Bilaterale Leber’sche Neuroretinitis stellata bei Borrelia burgdorferi Serokonversion. Klin Monatsbl Augenheildk 198:44–47

    Article  Google Scholar 

  • Schuman JS, Weinberg RS, Ridderhof J, Tucker M (1988) Experimental Lyme uveitis (abstract). Invest Ophthalmol Vis Sci (Suppl) 29:444

    Google Scholar 

  • Seidenberg KB, Leib ML (1990) Orbital myositis with Lyme disease. Am J Ophthalmol 109:13–16

    PubMed  CAS  Google Scholar 

  • Spalton DJ (1990) Lyme disease. Br J Ophthalmol 74:321–322

    Article  CAS  Google Scholar 

  • Steere AC (1989) Lyme disease. N Engl J Med 321:586–596

    Article  CAS  Google Scholar 

  • Steere AC, Bartenhagen NH, Craft JE, Hutchinson GJ, Newman JH, Rahn DW, Sigal LH, Spieler PN, Stenn KS, Malawista SE (1983) The early clinical manifestations of Lyme disease. Ann Intern Med 99:76–82

    PubMed  CAS  Google Scholar 

  • Steere AC, Duray PH, Kauman DJH, Wormser GP (1985) Unilateral blindness caused by infection with the Lyme disease spirochete, Borrelia burgdorferi. Ann Intern Med 103:382–384

    PubMed  CAS  Google Scholar 

  • Stiernstedt G, Gustavsson R, Karlsson M, Svenungsson B, Sköldenberg B (1988) Clinical manifestations and diagnosis of neuroborreliosis. Ann NY Acad Sci 539:46–55

    Article  PubMed  CAS  Google Scholar 

  • Weber K, Neubert U (1986) Clinical features of early erythema migrans disease and related disorders. Zentralbl Bakteriol Hyg (A) 263:209–228

    CAS  Google Scholar 

  • Wiegand W (1989) Augenbefunde bei Borreliose - bilaterale Panuveitis mit exsudativer Amotio. Fortsch Ophthalmol 86:659–662

    CAS  Google Scholar 

  • Wilk CM, Bialasiewicz AA, Ruprecht KW, Naumann GOH (1989) Bilaterale akute konfluierende Chorioditis disseminata bei Borrelia burgdorferi-Infektion. Klin Monatsbl Augenheildk 194:88–96

    Article  CAS  Google Scholar 

  • Winterkorn JMS (1990 Lyme disease: neurologic and ophthalmic manifestations. Surv Ophthalmol 35:191–204

    Article  PubMed  CAS  Google Scholar 

  • Winward KE, Smith JL, Culbertson WW, Paris-Hamelin AJ (1989) Ocular Lyme borreliosis. Am J Ophthalmol 108:651–657

    PubMed  CAS  Google Scholar 

  • Wu G, Lineoff H, Ellsworth RM, Haik BG (1986) Optic disc edema and Lyme disease. Ann Ophthalmol 18:252–255

    PubMed  CAS  Google Scholar 

  • Zierhut M, Kreissig I, Pickert A (1989) Panuveitis with positive serological tests for syphilis and Lyme borreliosis. J Clin Neuro ophthalmol 9:71–75

    CAS  Google Scholar 

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Authors
  1. U. Schönherr
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  2. F. Strle
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Editor information

Editors and Affiliations

  1. Rosenstr.6, 8000, München 2, Germany

    Klaus Weber (Dermatologist in Private Practice) (Dermatologist in Private Practice)

  2. Laboratory of Vectors and Pathogens, Rocky Mountain Laboratories, Department of Health and Human Services, Public Health Service,National Institutes of Health, National Institute of Allergy and Infectious Diseases, 59840, Hamilton, MT, USA

    Willy Burgdorfer Ph.D.,M.D.(h.c.)

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© 1993 Springer-Verlag Berlin Heidelberg

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Schönherr, U., Strle, F. (1993). Ocular Manifestations. In: Weber, K., Burgdorfer, W., Schierz, G. (eds) Aspects of Lyme Borreliosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77614-4_19

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  • DOI: https://doi.org/10.1007/978-3-642-77614-4_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77616-8

  • Online ISBN: 978-3-642-77614-4

  • eBook Packages: Springer Book Archive

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