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Familial Cancer Control pp 17–21Cite as

Down-Regulation of a Cell-Surface Glycoprotein Correlated with Rearrangement of Chromosome 1 in Human Breast Cancer Cells

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Part of the book series: ESO Monographs ((ESO MONOGRAPHS))

Abstract

The loss of heterozygosity of genes on chromosome 1q, 11p, 13q and 17p in human breast cancer cells has been reported [1–5]. However, reduction to homo- or hemizygosity has not been identified at a molecular level. In the current study, an attempt was made to identify any normal genes that may become inactivated in malignant cells, with associated loss of the gene products.

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References

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Author information

Authors and Affiliations

  1. School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA

    S. Ashraf Imam, Laura A. Mills & Clive R. Taylor

  2. M.D. Anderson Cancer Center, University of Texas, Houston, TX, 77030, USA

    Sen Pathak

Authors
  1. S. Ashraf Imam
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  2. Laura A. Mills
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  3. Sen Pathak
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  4. Clive R. Taylor
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Editor information

Editors and Affiliations

  1. Swiss Cancer League, Monbijoustraße 61, 3001, Bern, Switzerland

    Walter Weber (Medical Oncology Scientific Secretary) (Medical Oncology Scientific Secretary)

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© 1992 Springer-Verlag Berlin Heidelberg

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Imam, S.A., Mills, L.A., Pathak, S., Taylor, C.R. (1992). Down-Regulation of a Cell-Surface Glycoprotein Correlated with Rearrangement of Chromosome 1 in Human Breast Cancer Cells. In: Weber, W. (eds) Familial Cancer Control. ESO Monographs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77582-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-77582-6_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77584-0

  • Online ISBN: 978-3-642-77582-6

  • eBook Packages: Springer Book Archive

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