A Descriptive Study of the Characteristics of People with Helicobacter pylori Infection

  • L. Basso
  • J. Clune
  • S. Beattie
  • S. Lawlor
  • C. O’Morain
Conference paper


In 1893 the Italian pathologist G. Bizzozzero first described the presence of “curved bacilli” in the stomach of dogs [1]. During the following years other authors reported the detection of curved bacilli in the stomach of mammals such as rats and cats [2], in the stomach of patients with ulcerated neoplasms [3] and in the stomach of subjects with gastroduodenal peptic ulcers [4]. These findings were confirmed by later studies [5, 6]. However, none of these curved bacilli was ever isolated, and the theory of their role in human diseases progressively declined. However, in 1983 Warren and Marshall [7] succeeded in isolating spiraliform bacteria from human stomachs. These were first called Campylobacter pyloridis, then Campylobacter pylori and, eventually, Helicobacter pylori (HP). These two Australian researchers also suspected that antral gastritis and duodenal ulcers were of infectious origin and have to their credit the definition of the culture conditions necessary for the growth of this microorganism, so that it has been thereafter possible to perform several clinical studies on HP. Thus, we currently know that some 70%–92% of people with chronic gastritis are carriers of HP, and that it is found in about 86% and in 65% of subjects with duodenal and gastric ulcer [8], respectively.


Peptic Ulcer Pylorus Infection Total Positive Antral Gastritis Social Habit 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • L. Basso
    • 1
  • J. Clune
    • 2
  • S. Beattie
    • 1
  • S. Lawlor
    • 3
  • C. O’Morain
    • 1
  1. 1.Department of Gastroenterology and EndoscopyMeath HospitalDublinIreland
  2. 2.Department of DefenceDublinIreland
  3. 3.St. James’s HospitalDublinIreland

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