Helicobacter pylori Infection in Children

  • U. Blecker
  • A. Franckx-Goossens
  • S. Lauwers
  • Y. Vandenplas
Conference paper

Abstract

Helicobacter pylori is a recently discovered bacterium that has quickly awakened an enormous interest when a possible link was discovered between this microorganism and a number of diseases of the upper gastrointestinal tract [10, 11, 14]. For this reason H. pylori has been the subject of numerous clinical trials since its discovery 8 years ago. H. pylori-associated gastritis and peptic ulcer were initially reported in adult patients [17]. However, there has recently been increasing interest in the incidence of this microorganism in the paediatric age group [3, 4, 6, 9, 10, 12, 14].

Keywords

Fatigue Lactose Bismuth Ampicillin Constipation 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Blecker U, Renders F, Landers S, Vandenpias Y (1991) Syncopes leading to the diagnosis of a Helicobacter pylori positive chronic active haemorrhagic gastritis. Eur J Pediatr 150:560–561PubMedCrossRefGoogle Scholar
  2. 2.
    Börsch G, Schmidt G, Wegener M, Sandman M, Adamek R, Leverkus F, Reitemeyer E (1988) Campylobacter pylori: prospective analysis of clinical and histologic factors associated with colonization of the upper gastrointestinal tract. Eur J Clin Invest 18:133–138PubMedGoogle Scholar
  3. 3.
    Bujanover Y, Konik off F, Baratz M (1990) Nodular gastritis and Helicobacter pylori. J Pediatr Gastroenterol Nutr 11:41–44PubMedCrossRefGoogle Scholar
  4. 4.
    Czinn SJ, Speck WT (1989) Campylobacter pylori: a new pathogen? J Pediatr 114:670–672PubMedCrossRefGoogle Scholar
  5. 5.
    Czinn SJ, Dahms BB, Kaplan B, Rothstein FC (1986) Campylobacter-like organisms in association with symptomatic gastritis in children. J Pediatr 109:80–83PubMedCrossRefGoogle Scholar
  6. 6.
    Drumm B, Sherman P, Cutz E, Karmali M (1987) Association of Campylobacter pylori on the gastric mucosa with antral gastritis in children. N Engl J Med 316:1557–1561PubMedCrossRefGoogle Scholar
  7. 7.
    Drumm B, Sherman P, Chiasson D, Karmali M, Cutz E (1988) Treatment of Campylobacter pylori-associated antral gastritis in children with bismuth subsalicylate and ampicillin. J Pediatr 113:908–912PubMedCrossRefGoogle Scholar
  8. 8.
    Drumm B, Perez-Perez GI, Blaser MJ, Sherman PM (1990) Intrafamilial clustering of Helicobacter pylori infection. N Engl J Med 322:359–363PubMedCrossRefGoogle Scholar
  9. 9.
    Eastham EJ, Elliot SM (1987) Campylobacter pyloridis in children. Arch Dis Child 62:652Google Scholar
  10. 10.
    Glassman MS, Schwarz SM, Medow MS, Beneck D, Halata M, Berezin S, Newman LJ (1989) Campylobacter pylori-related gastrointestinal disease in children. Incidence and clinical findings. Dig Dis Sci 34:1501–1504PubMedCrossRefGoogle Scholar
  11. 11.
    Johnston BJ, Reed PI, Ali MH (1988) Prevalence of Campylobacter pylori in duodenal and gastric mucosa-relationship to inflammation. Scand J Gastroenterol 23:69–75CrossRefGoogle Scholar
  12. 12.
    Kilbridge PM, Dahms BB, Czinn SJ (1988) Campylobacter pylori-associated gastritis and peptic ulcer disease in children. Am J Dis Child 142:1149–1152PubMedGoogle Scholar
  13. 13.
    Kosunen TU, Höök J, Rautelin HI, Myllyl— G (1989) Age-dependent increase of Campylobacter pylori antibodies in blood donors. Scand J Gastroenterol 24:110–114PubMedCrossRefGoogle Scholar
  14. 14.
    Mahoney MJ, Wyatt JI, Littlewood JM (1988) Campylobacter pylori gastritis. Arch Dis Child 63:654–655CrossRefGoogle Scholar
  15. 15.
    Mitchell HM, Bohane T, Berkowicz J, Hazell SL, Lee A (1987) Antibody to Campylobacter pylori in families of index children with gastrointestinal illness due to Campylobacter pylori. Lancet ii: 681–682CrossRefGoogle Scholar
  16. 16.
    Oderda G, Ansaldi N, Boero M, Ponzetto A, Bellis D (1988) Campylobacter pylori in families of children with relapsing gastroduodenal disease due to C. pylori infection. Am J Gastroenterol 83:1437–1438PubMedGoogle Scholar
  17. 17.
    Warren JR, Marshall BJ (1983) Unidentified curved bacillion gastric epithelium in active chronic gastritis. Lancet i: 1273–1275Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • U. Blecker
    • 1
  • A. Franckx-Goossens
    • 1
  • S. Lauwers
    • 1
  • Y. Vandenplas
    • 1
  1. 1.Academic Children’s HospitalFree University of BrusselsBrusselsBelgium

Personalised recommendations