Detection of Phospholipases and Cytotoxic Activities of Helicobacter pylori

  • M. A. Daw
  • R. O’Moore
  • C. O’Morain


The production of phospholipases and cytotoxins is an important virulence factor in the pathogenesis of enteric bacteria. Phospholipases A have been detected in a large number of bacteria, including Escherichia coli and Vibrio parahaemolyticus [1], which may have a biological role to play. Phospholipases C are the most frequently studied phospholipases of bacterial origin and are believed to be toxic for the host cell.


Duodenal Ulcer Cytotoxic Activity Culture Filtrate Pylorus Strain Duodenal Ulcer Patient 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • M. A. Daw
    • 1
  • R. O’Moore
    • 2
  • C. O’Morain
    • 2
  1. 1.Department of Medical MicrobiologyFaculty of MedicineTripoliLibya
  2. 2.Departments of Biochemistry, St. James’s Hospital, and GastroenterologyMeath/Adelaide Hospital, Trinity CollegeDublinIreland

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