Morphology of Acute Pancreatitis

  • A. K. Foulis
Conference paper


Acute pancreatitis occurs in many different clinical settings, with varying causes. It is therefore very likely that factors as diverse as an impacted gall stone at the ampulla of Vater, hypothermia, or chronic alcoholism all initiate the disease process in different ways. Once an autodigestive process is started within the pancreas, however, a more uniform picture emerges.


Acute Pancreatitis Pancreatic Necrosis Gall Stone Gall Stone Pancreatitis Infected Pancreatic Necrosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Acosta JM, Ledesma CL (1974) Gall stone migration as a cause of acute pancreatitis. New Eng J Med 290:484–487PubMedCrossRefGoogle Scholar
  2. 2.
    Block S, Maier W, Bittner R, Biichler M, Malfertheiner P, Beger HG (1986) Identification of pancreas necrosis -in severe acute pancreatitis: imaging procedures versus clinical staging. Gut 27:1035–1042PubMedCrossRefGoogle Scholar
  3. 3.
    Bradley EL III (1988) Later complications of acute pancreatitis. In: Glazer G, Ranson JHC (eds) Acute pancreatitis. Bailliere Tindall, London, pp 390–431Google Scholar
  4. 4.
    Cadete-Leite A (1973) The arteries of the pancreas of the dog. An injection- corrosion and microangiographic study. Am J Anat 137:151–158PubMedCrossRefGoogle Scholar
  5. 5.
    Corfield AP, Cooper MJ, Williamson RCN et al. (1985) Prediction of severity in acute pancreatitis: prospective comparison of three prognostic indices. Lancet i:403–407Google Scholar
  6. 6.
    Donaldson LA, Williams RW, Schenk WG (1978) Experimental pancreatitis: effect of plasma and dextran on pancreatic blood flow. Surgery 84:313–321PubMedGoogle Scholar
  7. 7.
    Feiner H (1976) Pancreatitis after cardiac surgery: a morphologic study. Am J Surg 131:684–688PubMedCrossRefGoogle Scholar
  8. 8.
    Foulis AK (1980) Histological evidence of initiating factors in acute pancreatitis in man. J Clin Pathol 33:1125–1131PubMedCrossRefGoogle Scholar
  9. 9.
    Foulis AK (1982) Morphological study of the relation between accidental hypothermia and acute pancreatitis. J Clin Path 35:1244–1248PubMedCrossRefGoogle Scholar
  10. 10.
    Glazer G (1988) Classification and definitions in acute and chronic pancreatitis. In: Glazer G, Ranson JHC (eds) Acute pancreatitis. Bailliere Tindall, London, pp 37–50Google Scholar
  11. 11.
    Goodhead B (1969) Vascular factors in the pathogenesis of acute haemorrhagic pancreatitis. Ann R Coll Surg Engl 45:80–97PubMedGoogle Scholar
  12. 12.
    Graham DF, Wyllie FJ (1979) Prediction of gall-stone pancreatitis by computer. Br Med J i:515–517Google Scholar
  13. 13.
    Harada H, Ueda O, Yasuoka M et al. (1981) Histochemical studies on protein plugs obtained by endoscopic retrograde catheterization of the papilla. Gastroenterol Jpn 16:563–567PubMedGoogle Scholar
  14. 14.
    Harris PF (1979) In: Howat HT, Sarles H (eds) The exocrine pancreas. Saunders, London, p 21Google Scholar
  15. 15.
    Imrie CW, Benjamin IS, Ferguson JC et al. (1978) A single-centre double-blind trial of trasylol therapy in primary acute pancreatitis. Br J Surg 65:337–341PubMedCrossRefGoogle Scholar
  16. 16.
    Kelly TR (1976) Gall stone pancreatitis - pathophysiology. Surgery 80:488–492PubMedGoogle Scholar
  17. 17.
    Konok GP, Thompson AG (1969) Pancreatic ductal mucosa as a protective barrier in the pathogenesis of pancreatitis. Am J Surg 117:18–23PubMedCrossRefGoogle Scholar
  18. 18.
    Nordback I, Lauslahti K (1986) Clinical pathology of acute necrotising pancreatitis. J Clin Path 39:68–74PubMedCrossRefGoogle Scholar
  19. 19.
    Nordback I, Pessi T, Auvinen O, Autio V (1985) Determination of necrosis in necrotizing pancreatitis. Br J Surg 225–227Google Scholar
  20. 20.
    Ranson JHC, Spencer FC (1977) Prevention, diagnosis and treatment of pancreatic abscess. Surgery 82:99–106PubMedGoogle Scholar
  21. 21.
    Reber HA, Roberts C, Way LW (1979) The pancreatic duct mucosal barrier. Am J Surg 137:128–134PubMedCrossRefGoogle Scholar
  22. 22.
    Rich AR, Duff GL (1936) Experimental and pathological studies on the pathogenesis of acute haemorrhagic pancreatitis. Bull Johns Hopkins Hosp 58:212–258Google Scholar
  23. 23.
    Thai AP, Perry VF, Egner W (1957) A clinical and morphological study of 42 cases of fatal acute pancreatitis. Surg Gynecol Obstet 105:191–201Google Scholar
  24. 24.
    Warshaw AL, O’Hara PJ (1978) Susceptibility of the pancreas to ischemic injury in shock. Ann Surg 188:197–201PubMedCrossRefGoogle Scholar
  25. 25.
    Wharton GK (1932) The blood supply of the pancreas with special reference to the islands of Langerhans. Anat Rec 53:55–81CrossRefGoogle Scholar
  26. 26.
    Yaginuma N, Takahashi T, Saito K, Kyoguku M (1986) The microvasculature of the human pancreas and its relation to Langerhans islets and lobules. Pathol Res Pract 181:77–84PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • A. K. Foulis
    • 1
  1. 1.Division of Pathology, Royal InfirmaryUniversity of GlasgowGlasgowScotland

Personalised recommendations