Abstract
Recent advances in molecular biology methods have significantly increased the ability to detect genetic variation at the genomic level for forensic purposes. However, the quality requirements for blood, fresh or frozen tissue as a source of DNA are a practical limitation for typing the victim in order to conduct investigations on unsolved cases. Since paraffin embedded specimens are easily obtainable the ability to study this material would be of great value in current forensic practice.
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References
Cooke HJ, Schmidtke J, Gosden JR (1982) Characterisation of a human Y chromosome repeated sequence and related sequences in higher primates. Chromosoma 87: 491–502
Goelz SE, Hamilton SR, Vogelstein B (1985) Purification of DNA from formaldehyde fixed and paraffm embedded human tissue. Biochem Biophys Res Commun 130: 118–126
Jackson V (1978) Studies on histone organization in the nucleosome using formaldehyde as a reversible cross-linking agent. Cell Vol 15: 945–954
Maniatis T, Frisch EF and Sambrook J (1982) Molecular cloning: A laboratory manual. Cold Spring Harbor Laboratory, New York
Pflug W (1988) Subtyping of group specific component GC in microbloodstains and semen stains by isoelectric focusing in ultrathin immobilized pH gradient gels followed by enzyme detection. Electrophoresis 9: 443–448
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© 1992 Springer-Verlag Berlin Heidelberg
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Pötsch, L., Penzes, L., Prager-Eberle, M., Schneider, P.M., Rittner, C. (1992). Sex Determination by Genomic Dot Blot Hybridization and HLA DQα Typing by PCR from Fixed Tissues. In: Rittner, C., Schneider, P.M. (eds) Advances in Forensic Haemogenetics. Advances in Forensic Haemogenetics, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77324-2_27
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DOI: https://doi.org/10.1007/978-3-642-77324-2_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-55194-2
Online ISBN: 978-3-642-77324-2
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