Iso-Electric Focusing Study of Serum Proteins (GC, TF, PI and ORM) in Four Endogamous Groups of Maharashtra, Western India: Application in Paternity Testing
Iso-electric focusing (IEF) has become an important and powerful technique to discriminate genetic variability for several single gene systems. For example, Transferrin system was found to be monomorphic in most populations with starch gel electrophoresis, but analysis with IEF have clearly shown further microheterogeneity in this system, which makes TF a useful marker for population genetics and paternity determination. Several other serum protein systems HP, PI, GC and BF have shown similar microheterogeneity.
KeywordsMigration Arthritis Starch Europe Electrophoresis
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