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Treatment of Cerebral Vasospasm with Hypervolemia and Hypertension

  • A. Unterberg
  • J. Gethmann
  • A. von Helden
  • G.-H. Schneider
  • W. Lanksch
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 20)

Abstract

The term “cerebral vasospasm” is variously defined. Nowadays, the clinically used term stands for the delayed onset of a neurological deficit following subarachnoid hemorrhage, thought to be due to ischemia. There have been many attempts to prevent or treat cerebral vasospasm. The introduction of calcium channel blocking agents, such as nimodipine, has, however, also failed to completely abolish this complication. Cerebral vasospasm remains a challenging clinical problem. It remains the most important cause for mortality and morbidity of respective patients. The best current approach to treat vasospasm is to increase blood volume and to elevate blood pressure [1, 4–6].

Keywords

Cerebral Blood Flow Subarachnoid Hemorrhage Cerebral Vasospasm Cerebral Autoregulation Increase Blood Volume 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Kassell NF, Peerless SJ, Durward QJ, Beck DW, Drake CG, Adams HP (1982) Treatment of ischemic deficits from vasospasm with intravascular volume expansion and induced arterial hypertension. Neurosurgery 11:337–343PubMedCrossRefGoogle Scholar
  2. 2.
    Muizelaar JP, Becker DP (1986) Induced hypertension for the treatment of cerebral ischemia after subarachnoid hemorrhage. Direct effect on cerebral blood flow. Surg Neurol 25:317–325.PubMedCrossRefGoogle Scholar
  3. 3.
    Origitano TC, Wascher TM, Reichmann OH, Anderson DE (1990) Sustained increased cerebral blood flow with prophylactic hypertensive hypervolemic hemodilution (“triple-H” therapy) after subarachnoid hemorrhage. Neurosurgery 27:729–739PubMedCrossRefGoogle Scholar
  4. 4.
    Pritz MB (1984) Treatment of cerebral vasospasm. Usefulness of Swan-Ganz catheter monitoring of volume expansion. Surg Neurol 21:239–244PubMedCrossRefGoogle Scholar
  5. 5.
    Unterberg A, Marguth F (1988) Aktuelle Konzepte zu Pathogenese und Therapie des zerebralen Vasospasmus. Münch Med Wschr 130:543–544Google Scholar
  6. 6.
    Wilkins RH (1990) Cerebral vasospasm. Critical Reviews in Neurobiology 6:51–77PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • A. Unterberg
  • J. Gethmann
  • A. von Helden
  • G.-H. Schneider
  • W. Lanksch
    • 1
  1. 1.Abteilung für NeurochirurgieUniversitätsklinikum Rudolf Virchow, Freie Universität BerlinBerlin 65Germany

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