ARS Binding Factors from Saccharomyces cerevisiae
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Two proteins, designated ARS Binding Factors (ABF) 1 and 2, were identified several years ago as proteins that interact specifically with the yeast replication origin, ARS1 (Diffley and Stillman, 1988a). Subsequent analysis has revealed that ABF1 plays a key role in cell growth while ABF2 is involved in the maintenance of the mitochondrial genome. In this article, we summarize some of these results.
KeywordsHigh Mobility Group Protein Mitotic Stability Imperial Cancer Research Fund Plasmid Shuffle ABF2 Gene
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