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Über neuere Aspekte von Gehirn, Muskelarbeit, Sport und Psyche

  • W. Hollmann
  • K. de Meirleir
  • H. G. Fischer
  • R. Rost

Zusammenfassung

Das Gehirn stellt zweifellos das geheimnisvollste und am wenigsten erforschte Organ des Menschen dar. Es zeichnet sich nicht nur durch physikochemische Vorgänge wie bei allen anderen Organen aus, sondern produziert darüber hinaus den sog. „Seiner-Selbst-bewußten-Geist“. Der Gang der Evolution und Selektion ist durch 2 Sprünge gekennzeichnet: die Entstehung des Lebens und die Bildung des Bewußtseins. Die höchste Stufe von Bewußtsein erfuhr der Homo sapiens durch den eben charakterisierten Geist.

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Literatur

  1. 1.
    Acher R (1981) Evolution of neuropeptides. Trends Neurosci 9:225CrossRefGoogle Scholar
  2. 2.
    Ader R (ed) (1981) Psychoneuroimmunology. Academic Press, New YorkGoogle Scholar
  3. 3.
    Akil H, Watson SJ, Young E, Lewis ME, Khachaturian H, Walker JM (1984) Endogenous opioids: Biology function. Annu Rev Neurosci 7:223PubMedCrossRefGoogle Scholar
  4. 4.
    Alcohol Addiction (1972) A biochemical approach. Lancet 11:24Google Scholar
  5. 5.
    Ammon HPT (1984) Neue Aspekte zum Mechanismus der zentral erregenden Wirkung von Coffein. Dtsch Med Wochenschr 109:1491PubMedCrossRefGoogle Scholar
  6. 6.
    Arentz T, De Meirleir K, Hollmann W (1986) Die Rolle der endogenen Opioiden Peptide während Fahrradergometerarbeit. Dtsch Z Sportmed 37/7:210Google Scholar
  7. 7.
    Bittner H, Rippegather G, Völker K, Hollmann W, Forssmann WG (1986) Freisetzung kardialer Hormone unter ergometrischer Belastung. Dtsch Z Sportmed 37/11:356Google Scholar
  8. 8.
    Branchey L, Shaw S, Lieber CS (1981) Ethanol impairs tryptophan transport into the brain and depresses serotonin. Life Sci 29:2751PubMedCrossRefGoogle Scholar
  9. 9.
    Cavero I, Lefevre-Borg F, Lhoste F, Sabatier C, Richer C, Guidicelli JF (1984) Pharmacological, haemodynamic, and autnomic nervous system mechanisms responsible for the blood pressure and heart rate lowering effects of pergolide in rats. J Pharmacol Exp Ther 228:779PubMedGoogle Scholar
  10. 10.
    Changeux JP (1984) Der neuronale Mensch. Rowohlt, ReinbekGoogle Scholar
  11. 11.
    Chaouloff F (1989) Physical exercise and brain monoamines: a review. Acta Physiol Scand 137:1PubMedCrossRefGoogle Scholar
  12. 12.
    Creutzfeld OD (1987/88) Modelle des Gehirns - Modelle des Geistes? In: Dithfurt H von (Hrsg) Mannheimer Forum: „Ein Panorama der Naturwissenschaften”. Boehringer, MannheimGoogle Scholar
  13. 13.
    De Coverley Veale DMW (1987) Exercise and mental health. A review. Acta Psychiatr Scand 76:113PubMedCrossRefGoogle Scholar
  14. 14.
    De Meirleir K, Arentz T, Hollmann W, Haelst L van (1985) The role of endogenous opiates in thermal regulation of the body during exercise. Br Med J 290:739CrossRefGoogle Scholar
  15. 15.
    De Meirleir K, Baeyens L, l’Hermite M, l’Hermite-Baleriaux M, Hollmann W (1985) Exercise-induced prolactine release is related to anaerobiosis. J Clin Endocrinol Metab 69:1250CrossRefGoogle Scholar
  16. 16.
    De Meirleir K, l’Hermite-Batériaux M, l’Hermite M, Rost R, Hollmann W (1985) Evidence for serotoninergic control of exercise-induced prolactine secretion. Horm Metab Res 17/7:380PubMedCrossRefGoogle Scholar
  17. 17.
    De Meirleir K, Smitz J, Steirteghem A van, l’Hermite M, Hollmann W (1985) Dopaminergic and serotoninergic neurotransmitter systems involved in exercise-induced release of adenohypophyseal hormones. (6th Int. Symposium Biochem. of Exercise, Copenhagen)Google Scholar
  18. 18.
    De Meirleir K, Gerlo F, Hollmann W, Haelst L van (1987) Cardiovascular effects of pergolide mesylate during dynamic exercise. Br J Clin Pharmacol 23/5:633Google Scholar
  19. 19.
    De Meirleir K, Smitz J, Steirteghem A van, Hollmann W (1987) Serotonine antangonism during cexercise in man. Acta Cardiol 42/5:360Google Scholar
  20. 20.
    Demling L (1986) Gute Laune. Fortschr Med 7–8:64Google Scholar
  21. 21.
    Devoino LV, Idova GV (1973) The influence of some drugs on the immune response IV. Effect of serotonin, 5-hydroxytryptophan, iproniazid, p-chlorophenylalamine on the synthesis of IgM and IgG antibodies. Eur J Pharmacol 22:325PubMedCrossRefGoogle Scholar
  22. 22.
    Droste C (1987) Pathophysiologic schmerzhafter und stummer Myokardischämie. Herz 12/6:369PubMedGoogle Scholar
  23. 23.
    Diederich KW, Djonlagic H, Müller-Eschner M, Dageferde J, Hoffmann J (1982) Neurogene Endstreckenveränderungen im EKG. Med Klin 77/13:411Google Scholar
  24. 24.
    Dufaux B, Order U, Hollmann W (1983) Serum C-reaktives Protein und Immunkomplexe nach Belastung und Training. In: Heck H, Hollmann W, Liesen H, Rost R (Hrsg) Sport, Leistung und Gesundheit. Deutscher Ärzteverlag, Köln, S 305Google Scholar
  25. 25.
    Eccles JC, Zeier H (1984) Gehirn und Geist. Fischer, Frankfurt am MainGoogle Scholar
  26. 26.
    Fessel WJ, Chirata-Hibi M (1963) Abnormal leucocytes in schizophrenia. Arch Gen Psychiatry 9:601PubMedGoogle Scholar
  27. 27.
    Ganten D, Luft FC, Lang RE, Unger T (1986) Brain peptides in cardiovascular regulation. In: Kaufmann W, Börner G, Lang R, Meurer KA (eds) Primary hypertension. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  28. 28.
    Green AR, Grahame-Smith D, Grahame-Smith G (1976) Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptanine. Nature 260:487PubMedCrossRefGoogle Scholar
  29. 29.
    Grossman A, Bouloux P, Price P et al. (1984) The role of opioid peptides in the hormonal responses to acute exercise in man. Clin Sci 67:483PubMedGoogle Scholar
  30. 30.
    Hall NR, Goldstein AL (1983) The thymus-brain connection: interactions between thymosin and the neuroendocrine system. Lymphokine Res 211–216Google Scholar
  31. 31.
    Herholz K, Buskies W, Rist M, Pawlik G, Hollmann W, Heiss WD (1987) Regional cerebral blood flow in man at rest and during exercise. J Neurol 234:9PubMedCrossRefGoogle Scholar
  32. 32.
    Hollmann W (1983) Körperliches Training und Hirnleistungsinsuffizienz — Terra incognita. Therapiewoche 33/12:1584Google Scholar
  33. 33.
    Hollmann W (1987) Stimmung, Schmerz, Hirndurchblutung und muskuläre Arbeit. In: Graul EH, Pütter S, Loew D (Hrsg) Das Gehirn und seine Erkrankungen. Medicine, IserlohnGoogle Scholar
  34. 34.
    Hollmann W (1987) Hirndurchblutung und Körperarbeit. Herz Sport Gesundheit 4/2:64Google Scholar
  35. 35.
    Hollmann W, Hettinger T (21980) Sportmedizin — Arbeits- und Trainingsgrundlagen. Schattauer, StuttgartGoogle Scholar
  36. 36.
    Hollmann W, De Meirleir K, Herholz K, Heiss WD, Bittner H, Völker K, Forssmann G (1987) Regional cerebral blood flow, neurohormonal, and cardiac hormonal reactions during exercise. [International Symposium on Exercise Physiology (in memoriam S. Kozlowski) Baranow/Polen]Google Scholar
  37. 37.
    Hughes J, Smith TW, Kosterlitz HW, Fothergill LA, Morgan MA, Morris HR (1975) Identification of two related pentapeptides from the brain with potent opiate agonist activity. Nature 258:577PubMedCrossRefGoogle Scholar
  38. 38.
    Ingvar DH, Sjölund B, Ardö A (1976) Correlation between dominant EEG frequency, cerebral oxygen uptake, and blood flow. Eletroencephalogr Clin Neurophysiol 41:268CrossRefGoogle Scholar
  39. 39.
    Jungmann H (1981) Psychogene Herzrhythmusstörungen bei Koronarerkrankten. Therapiewoche 31:907Google Scholar
  40. 40.
    Kandel ER, Schwartz JH (1985) Principles of endurai sciences. Elsevier, New YorkGoogle Scholar
  41. 41.
    Klimenko VN (1985) Neural hypothalamic mechanisms in the development of the immune response. In: Korneva EA, Klimenko VN, Shkhinck EK (eds) Neurohumeral maintenace of immune homeostasis. Univ Chicago Press, Chicago, p 159Google Scholar
  42. 42.
    Koff WC, Dunegan MA (1985) Modulation of macrophagenediated tumoricidal activity by neuropeptides and neurohormones. J Immuno 135:350Google Scholar
  43. 43.
    Kuschinsky W, Wahl M (1978) Local chemical and neurogenic regulation of cerebral vascular resistance. Physiol Rev 58:656PubMedGoogle Scholar
  44. 44.
    Larbig W (1981) Psychologie und Biochemie psychosomatischer Erkrankungen. Med Klin 76/23:636PubMedGoogle Scholar
  45. 45.
    Lassen NA (1974) Control of cerebral circulation in health and disease. Cire Res 34:749Google Scholar
  46. 46.
    Li CH (1977) Beta-endorphine: a pituitary peptide with potent morphine-like reactivity. Arch Biochem Biophys 183:595Google Scholar
  47. 47.
    Liesen H, Dufaux B, Hollmann W (1977) Modifications of serumglycoproteines the days following a prolonges physical exercise and the influence of physical training. Eur J Appl Physiol 37:243CrossRefGoogle Scholar
  48. 48.
    Lown B (1987) Brain, heart, and sudden death. Z Kardiol [Suppl 2] 76Google Scholar
  49. 49.
    Luger A (1987) Acute hypothalamic-pituitary adrenal responses to the stress of treadmill exercise. N Engl J Med 316:1309PubMedCrossRefGoogle Scholar
  50. 50.
    Mariani J (1983) Elimination of synapses during the development of the central nervous system. Prog Brain Res 58:383PubMedCrossRefGoogle Scholar
  51. 51.
    Mathews PM, Froelich CJ, Sibbit WI, Bankhurst AD (1983) Enhancement of natural cytotoxity by beta-endorphin. J Immunol 130:1658PubMedGoogle Scholar
  52. 52.
    Melville KI (1966) Cardiac ischemic changes induced by central nervous system stimulation. In: Raab W (ed) Prevention of ischemic heart desease. Thomas, Spring- field/ILGoogle Scholar
  53. 53.
    Olds, J, Milner P (1954) Positive reinforcement producted by electrical stimulation of septal area and other regions of rat brain. J Comp Physiol Psychol 47:419PubMedCrossRefGoogle Scholar
  54. 54.
    Parati G, Pomidossi G, Mancia G (1986) Neural mechanism in human cardiovascular regulation. In: Schmidt TH, Dembroski TM, Blümchen G (eds) Biological and psychological factors in cardiovascular disease. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  55. 55.
    Prigogine I, Balescu R (1956) Phénomènes cycliques dans la thermodynamique des processus irréversibles. Bull Acad R Belg Clin Sci 42:256Google Scholar
  56. 56.
    Raab W (1963) Neurogenic multifocal distraction of myocardial tissue. Ref Can Biol 22:217Google Scholar
  57. 57.
    Raab W (ed) (1966) Prevention of ischemic heart disease. Thomas, Springfield/ILGoogle Scholar
  58. 58.
    Raglin JS (1990) Exercise and mental health. Sports Med 9/6:323PubMedCrossRefGoogle Scholar
  59. 59.
    Rose G (1980) Can the neurosciences explain the mind? Trends Neurosci 5:1Google Scholar
  60. 60.
    Routtenberg A (91988) Das Belohnungssystem des Gehirns. In: Gehirn und Nervensystem. Woraus sie bestehen — wie sie funktionieren — was sie leisten. Spektrum der Wissenschaft, Heidelberg, S 160–176Google Scholar
  61. 61.
    Roux W (1985) Entwicklungsmechanik der Organismen. LeipzigGoogle Scholar
  62. 62.
    Rozanski A, Bairey CN et al. (1988) Mental stress and the induction of silent myocardial ischemia in patients with coronary artery disease. N Engl J Med 318/16:1005PubMedCrossRefGoogle Scholar
  63. 63.
    Schaefer H, Blohmke H (1977) Herzkrank durch psychosozialen Streß. Hüthig, HeidelbergGoogle Scholar
  64. 64.
    Schopf GW (1978) The evolution of the earliest cells. Sci Am 239/3:85CrossRefGoogle Scholar
  65. 65.
    Schwarz L, Kindermann W (1989) Beta-Endorphin, Cortisol und Katecholamine während fahiradergometrischer Ausdauerbelastungen und Feldtestuntersuchungen. Dtsch Z Sportmed 40/5:160Google Scholar
  66. 66.
    Searle G (1984) Minds, brains, and science. Harvard Univ Press, CambridgeGoogle Scholar
  67. 67.
    Selye H (1950) The physiology and pathology of exposure to stress. Acta, MontrealGoogle Scholar
  68. 68.
    Shkhvatsabaya IK (1966) Experimental production of myocardial lesions by disturbing the central nervous system. In: Raab W (ed) Prevention of ischemic heart disease. Thomas, Springfield/ILGoogle Scholar
  69. 69.
    Smith EM, Blalock JE (1981) Human lymphocyte production of corticotrophin and endorphin-like substances: asssociation with leucocytic interferon. Proc Natl Acad Sci USA 78:7530PubMedCrossRefGoogle Scholar
  70. 70.
    Snyder SH (1986) Drugs and the brain. Scientific American Books, New YorkGoogle Scholar
  71. 71.
    Sologub JB (1976) Elektroenzephalographie im Sport. Barth, LeizpzigGoogle Scholar
  72. 72.
    Solomon GF (1987) Psychoneuroimmunology: Interactions between central nervous system and immune system. J Neurosci Res 18:1PubMedCrossRefGoogle Scholar
  73. 73.
    Solomon GF, Moos RH (1964) Emotions, immunity, and disease. A speculative theoretical integration. Arch Gen Psychiatry 11:657PubMedGoogle Scholar
  74. 74.
    Stephan H (1972) Evolution of primate brains. In: Tuttle R (ed) The functional and evolutionary biology of primates. Adline, ChicagoGoogle Scholar
  75. 75.
    Taggert B, Gibbons D, Sommerville B (1969) Some effects of motorcar driving on the normal and abnormal heart. Br Med J 4:130CrossRefGoogle Scholar
  76. 76.
    Uexküll T von (1988) Die Entstehung der psychosomatischen Medizin aus der Geschichte des Leib-Seele-Dualismus. Med Klin 83:37Google Scholar
  77. 77.
    Uhlenbruck G, Order U (1987) Perspektiven, Probleme und Prioritäten: Sportimmunologie - die nächsten 75 Jahre? Dtsch Z Sportmed [Sonderheft] S 40Google Scholar
  78. 78.
    Vidal G (1984) The oldest eukariotic cells. Sci Am 250/2:32CrossRefGoogle Scholar
  79. 79.
    Washburn SL (1978) The evolution of man. Sci Am 239/3:146CrossRefGoogle Scholar
  80. 80.
    Weihe E (1987) Peripheral innervation of the heart. In: Arnim T von, Marx A (eds) Silent ischemia. Darmstadt, SteinkopffGoogle Scholar
  81. 81.
    Weihe E, Nohr D, Gauweiler B, Fink T, Nowak E, Konrad S (1988) Immunohistochemical evidence for a diversity of opioid coding in peripheral sympathetic, parasympathetic and sensory neurones: A general principle of prejunctional opioid autoinhibition? In: Illes P, Farsang C (eds) Regulatory role of opioid peptides. VCH, WeinheimGoogle Scholar
  82. 82.
    Weihe E, Norh D, Hartschuh W (1988) Immunohistochemical evidence for a co-transmitter role of opioid peptides in primary sensory neurones. Prog Brain Res 74:189PubMedCrossRefGoogle Scholar
  83. 83.
    Weiß N, Fuhrmansky J, Lulay R, Weicker H (1985) Häufigkeit und Ursache von Im- munglobulinmangel bei Sportlern. Dtsch Z Sportmed 36/5:146Google Scholar
  84. 84.
    White E (1981) Thalamocortical synaptic relations. In: Schmitt F et al. (eds) The organisation of the cerebral cortex. MITPress, Cambridge/MAGoogle Scholar
  85. 85.
    Wise R (1980) The dopamin synapse and the notion of „Pleasure center” in the brain. Trends Neurosci 4:91CrossRefGoogle Scholar
  86. 86.
    Wurtman RJ (1984) Nährstoffe, die Gehirnfunktionen fördern. Nervenheilkunde 3:33Google Scholar
  87. 87.
    Yates A, Leehey K, Shissiak CM (1983) Running — an analogue of anorexia? N Engl J Med 308:251PubMedCrossRefGoogle Scholar
  88. 88.
    Zhou D, Khan S, Forde J, Hirsch KR (1985) Coffeine tolerance: Behavioral electrophysiological and neurochemical evidence. Life Sci 36:2347CrossRefGoogle Scholar
  89. 89.
    Zurabaki G, Benedik M, Kamb BJ, Abrams JS, Zurawski SM, Lee FD (1986) Activation of maus T-helper cells induces abundant preproencephalin RNH synthesis. Science 232:772CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • W. Hollmann
  • K. de Meirleir
  • H. G. Fischer
  • R. Rost

There are no affiliations available

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