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The Pathology of Bioprosthetic Heart Valves and Allografts

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Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 86))

Abstract

Valve surgery continues to be a challenging aspect of current cardiac surgical practice, where each year some 30 000 patients in the United States (Miller et al. 1987) present for what might appear to be an easy procedure: the replacement of a heart valve.

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References

  • Akins CW et al. (1979) Preoperative evaluation of subvalvular fibrosis in mitral stenosis: a predictive factor in conservative vs. replacement surgical therapy. Circulation 60 (Suppl I): I-71–I-76

    PubMed  CAS  Google Scholar 

  • Alam M et al. (1979) M-mode and two dimensional echocardiographic features of porcine valve dysfunction. Am J Cardiol 43: 502–509

    Article  PubMed  CAS  Google Scholar 

  • American Association of Tissue Banks (1987) technical manual for tissue banking. AATB, Arlington, Va.

    Google Scholar 

  • Angell JD et al. (1976) A fresh viable human heart valve bank — sterilization, sterility testing and cryogenic preservation. Transplant Proc 8 (Suppl I): 127–141

    Google Scholar 

  • Angell WW, Maguire PJ (1990) The effect of stent mounting on tissue valves. Circulation 82 (Suppl III): 763

    Google Scholar 

  • Angell WW et al. (1991) Effect of stent mounting on tissue valves for aortic valve replacement. J Cardiac Surg 6 (Suppl): 595–599

    CAS  Google Scholar 

  • Antunes MJ et al. (1984) Performance of glutaraldehyde-preserved porcine bioprosthesis as a mitral valve substitute in a young population group. Ann Thorac Surg 37: 387–392

    Article  PubMed  CAS  Google Scholar 

  • Armiger LC et al. (1983) Histological assessment of orthotopic aortic valve leaflet allografts: its role in selecting graft pretreatment. Pathology 15: 67–73

    Article  PubMed  CAS  Google Scholar 

  • Badduke BR et al. (1991) Pregnancy and childbearing in a population with biologic valvular prostheses. J Thorac Cardiovasc Surg 102: 179–186

    PubMed  CAS  Google Scholar 

  • Bank HL, Brockbank KGM (1987) Basic principles of cryobiology. J cardiac Surg 2 (Suppl): 137–143

    CAS  Google Scholar 

  • Barrat-Boyes BG (1964) Homograft aortic valve replacement and aortic incompetence and stenosis. Thorax 19: 131–150

    Article  Google Scholar 

  • Barrat-Boyes BG (1965a) A method for preparing and inserting a homograft aortic valve. Br J Surg 52: 847–856

    Article  Google Scholar 

  • Barrat-Boyes BG (1969) Aortic homograft valve replacement: a longterm followup of an initial series of 101 patients. Circulation 40: 763–769

    Google Scholar 

  • Barrat-Boyes BG (1979) Cardiothoracic surgery in the antipodes. J Thorac Cardiovasc Surg 78: 804–822

    Google Scholar 

  • Barrat-Boyes BG et al. (1965) Homograft valve replacement for aortic valve disease. Thorax 20: 495–500

    Article  Google Scholar 

  • Becker RM et al. (1980) Hemodynamic performance of the Ionescu-Shiley prosthesis. J Thorac Cardiovasc Surg 80: 613–620

    PubMed  CAS  Google Scholar 

  • Billingham ME et al. (1979) Bacterial infection in implanted porcine heterografts. A histopathologic and ultrastructural study. In: Sebening F, Klövekorn WP, Meisner H, Struck E (eds) Bioprosthetic cardial valves. Eberl, Immenstadt, p 281

    Google Scholar 

  • Bioimplant Services (1991). Heart valve transplant manual, part 2. Leiden

    Google Scholar 

  • Bloch G, Voulse PR, Poulain H et al. (1982) Mid-and long-term evaluation of porcine bioprosthetic valves; a 6 year experience. In: Cohn LH, Gallucci V (eds) Cardiac bioprostheses, Yorke Medical Books, New York, pp 70–76

    Google Scholar 

  • Bloomfield P et al. (1986) A prospective evaluation of the Björk-Shiley, Hancock, and Carpentier-Edwards heart valve prostheses. Circulation 73: 1213–1222

    Article  PubMed  CAS  Google Scholar 

  • Bodnar E et al. (1990) Nonviable aortic homografts. In: Bodnar E (ed) Surgery for heart valve disease. ICR London, pp 494–500

    Google Scholar 

  • Bolooki H et al. (1983) Failure of Hancock xenograft valve. Importance of valve position (4 to 9 year follow up). Ann Thorac Surg 36: 246–252

    Article  PubMed  CAS  Google Scholar 

  • Bolooki H et al. (1986) Comparison of long-term results of Carpentier-Edwards and Hancock Bioprosthetic valves. Ann Thorac Surg 42: 494–499

    Article  PubMed  CAS  Google Scholar 

  • Bortolotti U et al. (1980) Left ventricular rupture following mitral valve replacement with a Hancock bioprosthesis. Chest 77: 235–237

    Article  PubMed  CAS  Google Scholar 

  • Bortolotti U et al. (1982) Pregnancy in patients with a porcine valve bioprosthesis. Am J Cardiol 50: 1051–4

    Article  PubMed  CAS  Google Scholar 

  • Bortolotti U et al. (1985) Results of reoperation for primary tissue failure of porcine bioprostheses J. Thorac Cardiovasc Surg 90: 564–569

    PubMed  CAS  Google Scholar 

  • Bortolotti U et al. (1987) Long-term durability of Hancock porcine bioprosthesis following combined mitral and aortic valve replacement: an 11-year experience. Ann Thorac Surg 44: 139–144

    Article  PubMed  CAS  Google Scholar 

  • Brais MP et al. (1985) Ionescu-Shiley pericardial xenografts: follow-up of up to 6 years. Ann Thorac Surg 39: 105–111

    Article  PubMed  CAS  Google Scholar 

  • Brockbank KGM, Bank HL (1987) Measurement of postcryopreservation viability. J Cardiac Surg 2 (Suppl): 145–151

    CAS  Google Scholar 

  • Carpentier A et al. (1968) Mitral and tricuspid valve replacement with frame mounted aortic heterografts. J Thorac Cardiovasc Surg 56: 388–394

    PubMed  CAS  Google Scholar 

  • Carpentier A et al (1969) Biological factors affecting long-term results of valvular heterografts. J Thorac Cardiovasc Surg 58: 467–483

    PubMed  CAS  Google Scholar 

  • Carpentier A et al. (1982) Continuing improvement in valvular prostheses. J Thorac Cardiovasc Surg 83: 27–42

    PubMed  CAS  Google Scholar 

  • Carpentier A et al. (1984) Techniques for prevention of calcification of valvular bioprostheses. Circulation 70 (Part 2): 1165–1168

    Google Scholar 

  • Cipriano PR et al (1984) Calcification of aortic versus mitral porcine bioprosthetic heart valves: a radiographic study comparing the amounts of calcific deposits in valves explanted from the same patient. Am J Cardiol 54: 1030–1032

    Article  PubMed  CAS  Google Scholar 

  • Cobanoglu A et al. (1987) A tri-institutional comparison of tissue and mechanical valves using a patient-oriented definition of “treatment failure”. Ann Thorac Surg 43: 245–253

    Article  PubMed  CAS  Google Scholar 

  • Cohn LH (1979) Bioprosthetic cardiac valves - anticoagulation or not? In: Sebening F, Klövekom WP, Meisner H, Struck E (eds) Bioprosthetic cardiac valves. Deutsches Herzzentrum, Munich, p 107

    Google Scholar 

  • Cohn LH et al. (1984) Early and late risk of aortic valve replacement J Thorac Cardiovasc Surg 88: 695–705

    PubMed  CAS  Google Scholar 

  • Copeland JG et al. (1977) Long-term follow-up after isolated aortic valve replacement. J Thorac Cardiovasc Surg 74: 875–889

    PubMed  CAS  Google Scholar 

  • Cornhill JF (1977) An aortic-left ventricular pulse duplicator used in testing prosthetic aortic heart valves. J Thorac Cardiovasc Surg 73: 550–562

    PubMed  CAS  Google Scholar 

  • Cosgrove DM et al. (1985) In vivo hemodynamic comparison of porcine and pericardial valves. J Thorac Cardiovasc Surg 89: 358–368

    PubMed  CAS  Google Scholar 

  • Craver JM et al. (1978) Late hemodynamic evaluation of Hancock modified orifice aortic bioprosthesis. Circulation 60 (Suppl I): 93

    Google Scholar 

  • Curcio CA et al. (1981) Calcification of glutaraldehyde-preserved porcine xenografts in young patients. J Thorac Cardiovasc Surg 81: 621–625

    PubMed  CAS  Google Scholar 

  • Deviri E et al. (1985). Pregnancy after valve replacement with porcine xenograft prosthesis. Surg Gynecol Obstet 160: 437–443

    PubMed  CAS  Google Scholar 

  • Disesa VJ et al. (1990) Heart transplantation for intractable prosthetic valve endocarditis. J Heart Transplant 9 (2): 142

    PubMed  CAS  Google Scholar 

  • Douglas PS et al. (1984) Clinical comparison of St. Jude and porcine aortic valve prosthesis. Circulation 72 (Suppl II): 135

    Google Scholar 

  • Drury PJ et al. (1986) Distribution of flexibility in the porcine aortic root and in cardiac support frames. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical, New York, pp 580590

    Google Scholar 

  • Dunn JM (1981) Porcine valve durability in children. Ann Thorac Surg 32: 357–368

    Article  PubMed  CAS  Google Scholar 

  • Edmunds LH Jr (1982) Thromboembolic complications of current cardiac valvular prostheses. Ann Thorac Surg 34: 96–106

    Article  PubMed  Google Scholar 

  • Edmunds LH, Clark RE et al. (1988) Guidelines for reporting morbidity and mortality after cardiac valvular operation. J Thorac Cardiovasc Surg 96: 351–353

    PubMed  Google Scholar 

  • Egloff L, Rothlin H, Turina M, Senning A et al. (1980) Isolated aortic valve replacement with the BjörkShiley tilting disc prosthesis and the porcine bioprosthesis. Eur Heart J 1 (2): 123–127

    PubMed  CAS  Google Scholar 

  • Farah E et al. (1984) Thromboembolic and hemorrhage risk in mechanical and biologic aortic prosthesis. Eur Heart J 5 (Suppl D): 43

    PubMed  Google Scholar 

  • Ferrans VJ et al. (1978) Ultrastructure of Hancock porcine valvular heterografts; pre-and post-implantation changes. Circulation 58 (Suppl I): 10

    Google Scholar 

  • Ferrans VJ et al. (1980) Calcific deposits in porcine bioprostheses; structure and pathogenesis Am J Cardiol 46: 721–734

    Article  PubMed  CAS  Google Scholar 

  • Fiddler GI et al. (1983) Calcification of glutaraldehyde preserved porcine and bovine xenograft valves in young children. Ann Thorac Surg 35: 257–261

    Article  PubMed  CAS  Google Scholar 

  • Fishbein MC et al. (1977) Pathologic findings after cardiac valve replacement with glutaraldehyde-fixed porcine valves. Am J Cardiol 40: 331–337

    Article  PubMed  CAS  Google Scholar 

  • Fontan F et al. (1976) Comparative study of the Björk-Shiley valve and aortic valve homograft in mitral valve replacement. In: Kalmanson D (ed) The mitral valve. Edward Arnold, London, pp 497–503

    Google Scholar 

  • Frank S et al. (1973) Natural history of valvular aortic stenosis. Br Heart J 35: 41–46

    Article  PubMed  CAS  Google Scholar 

  • Gabbay S et al. (1980) In vitro hydrodynamic comparison of St. Jude, Björk-Shiley and Hall-Kaster valves. Trans Am Soc Artif Intern Organs 26: 731

    Google Scholar 

  • Gabbay S et al. (1984) Hemodynamics and durability of mitral bioprosthesis - an in vitro study. Eur Heart J 65: 5 (Suppl)

    PubMed  Google Scholar 

  • Gallo I et al. (1986) Six to ten year follow-up with patients with the Hancock cardiac bioprosthesis. J Thorac Cardiovasc Surg 92: 14–20

    PubMed  CAS  Google Scholar 

  • Gallucci V et al. (1982) Heart valve replacement with the Hancock bioprosthesis: a 5–11 year follow-up. In: Cohn LH, Gallucci V (eds) Cardiac bioprostheses. Yorke Medical, New York, pp 9–24

    Google Scholar 

  • Gallucci V et al. (1986) The Hancock porcine valve 15 years later: an analysis of 575 patients. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical, New York, pp 91–97

    Google Scholar 

  • Gardner Tl et al. (1982) Valve replacement in children: a fifteen-year perspective. J Thorac Cardiovasc Surg 83: 178–185

    PubMed  CAS  Google Scholar 

  • Gavin JB et al (1973) The histopathology of “fresh” human aortic valve allografts. Thorax 28: 482–488

    Article  PubMed  CAS  Google Scholar 

  • Geha AS (1987) Long-term outcome of cardiac valve substitutes. Ann Thorac Surg 44: 566–567

    Article  PubMed  CAS  Google Scholar 

  • Geha AS et al (1979) Late failure of porcine valve heterografts in children. J Thorac Cardiovasc Surg 78: 351–364

    PubMed  CAS  Google Scholar 

  • Geroulanos S (1985) Bioprothesen. Hans Huber, Bern.

    Google Scholar 

  • Gonzalez-Lavin L et al. (1984) Thromboembolism in bleeding after mitral valve replacement with porcine valves: influence of thromboembolic risk factors. J Surg Res 35: 508

    Article  Google Scholar 

  • Gorlin R Gorlin SG (1951) Hydraulic formula for the calculation of the area of stenotic mitral valve, other cardial valves, and central circulatory shunts. Am Heart J 41: 1

    Article  PubMed  CAS  Google Scholar 

  • Hammermeister KE et al. (1987) Comparison of outcome after valve replacement with a bioprosthesis vs. a mechanical prosthesis: initial 5 year results of a randomized trial. J Am Coll Cardiol 10: 719–732

    Article  PubMed  CAS  Google Scholar 

  • Hammond GL et al. (1987) Biological versus mechanical valves. J Thorac Cardiovasc Surg 93: 182–198

    PubMed  CAS  Google Scholar 

  • Hartz RS et al (1986) Eight-year experience with porcine bioprosthetic cardiac valves. J Thorac Cardiovasc Surg 91: 910–917

    PubMed  CAS  Google Scholar 

  • Hopkins RA (1989a) Historical development of the use of homograft valves. In: Hopkins RA (ed) Cardiac reconstructions with allograft valves. Springer, New York, pp 3–13

    Chapter  Google Scholar 

  • Hopkins RA (1989b) Rationale for use of cryopreserved allograft tissues for cardiac reconstructions. In: Hopkins RA (ed) Cardiac reconstructions with allograft valves. Springer, New York, pp 15–20

    Chapter  Google Scholar 

  • Horstkotte D et al. (1983) Central hemodynamics at rest and during exercise after mitral valve replacement with different prostheses. Circulation 68 (Suppl II): 161

    Google Scholar 

  • Human DG et al. (1982) Mitral valve replacement in children. J Thorac Cardiovasc Surg 83: 873–877

    PubMed  CAS  Google Scholar 

  • Hume M et al. (1970) Venous thrombosis and pulmonary embolism. Harvard Press, Cambridge, p 455

    Google Scholar 

  • Hurst JW (ed) (1982) The heart, artery and veins. McGraw-Hill, New York.

    Google Scholar 

  • Ilbawi MN et al. (1986) Long-term results of porcine valve insertion for pulmonary regurgitation following repair of tetralogy of Fallot. Ann Thorac Surg 41: 478–482

    Article  PubMed  CAS  Google Scholar 

  • Ionescu MI (1986) The pericardial xenograft valve: mode of failure and possible remedial developments. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves: proceedings of the third international symposium. Yorke Medical, New York, pp 245–251

    Google Scholar 

  • Ionescu MI, Tandon AP, Saunders NR, Chidambaram M, Smith DR (1982) Clinical durability of the pericardial xenograft valve: 11 years experience. In: Cohn LH, Gallucci V (eds) Cardiac bioprostheses. Yorke Medical, New York, pp 42–60

    Google Scholar 

  • Ishihara T et al. (1981) Occurrence and the significance of endothelial cells in implanted porcine bioprosthetic valves. Am J Cardiol 48: 443–454

    Article  PubMed  CAS  Google Scholar 

  • Ivert TSA et al. (1984) Prosthetic valve endocarditis. Circulation 69: 223–227

    Article  PubMed  CAS  Google Scholar 

  • Jaffe WM et al. (1989) Doppler echocardiography in the assessment of the homograft aortic valve. Am J Cardiol 63: 1466–1470

    Article  PubMed  CAS  Google Scholar 

  • Jaffe WM et al. (1990) Rest and exercise hemodynamics of 20 to 23 mm allograft, Medtronic intact (porcine) and St.-Jude medical valves in the aortic position. J Thorac Cardiovasc Surg 100: 167–174

    PubMed  CAS  Google Scholar 

  • Jamieson WRE et al. (1989) Cardiac valve replacement in the elderly: clinical performance of biological prostheses. Ann Thorac Surg 48: 173–185

    Article  PubMed  CAS  Google Scholar 

  • Janusz MT et al. (1982) Experience with the Carpentier-Edwards porcine valve prosthesis in 700 patients. Ann Thorac Surg 34: 625–633

    Article  PubMed  CAS  Google Scholar 

  • Johnson A et al. (1978) Evaluation of the in vivo function of the Hancock porcine xenograft in the aortic position. J Thorac Cardiovasc Surg 75: 600–605

    Google Scholar 

  • Jones EL (I 989) Freehand homograft aortic valve replacement - the learning curve: a technical analysis of the first 31 patients. Ann Thorac Surg 48: 26–32

    Google Scholar 

  • Joyce LD et al. (1984) Comparison of porcine valve xenografts with mechanical prostheses. J Thorac Cardiovasc Surg 88: 102–113

    PubMed  CAS  Google Scholar 

  • Khaghani A et al. (1976) Patient status 10 years or more after aortic valve replacement using antibiotic sterilized aortic homografts. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical Books, New York, pp 38–46

    Google Scholar 

  • Khan SS et al. (1990) Differences in Hancock and Carpentier-Edwards porcine xenograft aortic valve hemodynamics. Circulation 82 (Suppl IV): 117–124

    Google Scholar 

  • Kirklin JW, Barrat-Boyes BG (1986) Cardiac surgery. Churchill Livingstone, New York, pp 421–422

    Google Scholar 

  • Kirklin JW et al. (1987) Intermediate term fate of cryopreserved allograft and xenograft valve conduits. Ann Thorac Surg 44: 598–606

    Article  PubMed  CAS  Google Scholar 

  • Kirklin JW et al. (1989) Surgical treatment of prosthetic valve endocarditis with homograft aortic valve replacement. J Cardiac Surg 4: 340–347

    Article  CAS  Google Scholar 

  • Knight JP et al. (1984) Bacterial associated porcine heterograft heart valve calcification. Am J Cardiol 53: 370–372

    Article  PubMed  CAS  Google Scholar 

  • Konertz W et al. (1991) Pulmonalklappen-Allograft in Aortenposition–Frühergebnisse bei 30 konsekutiven Patienten. Z Herz-Thorax-Gel`iBchir 5: 68–74

    Google Scholar 

  • Konertz W et al. (1992) Technique of aortic valve replacement with the Edwards stentless aortic bioprothesis 2500. Eur J Cardiothorac Surg 6: 274–277

    Article  PubMed  CAS  Google Scholar 

  • Kwong K-H et al. (1967) Experimental use of immunosuppression in aortic valve homografts and heterografts. J Thorac Cardiovasc Surg 54: 199–207

    Google Scholar 

  • Laks H et al. (1980) Left atrial-left ventricular conduit for relief of congenital mitral stenosis in infancy. J Thorac Cardiovasc Surg 80: 782–787

    PubMed  CAS  Google Scholar 

  • Lam CR et al. (1952) An experimental study of aortic valve homografts. Surg Gynecol Obstet 94: 129–135

    PubMed  CAS  Google Scholar 

  • Lang RM et al (1985) Pregnancy and heart disease. Clin Perinatol 12: 551–567

    PubMed  CAS  Google Scholar 

  • Lange PL, Hopkins RA (1989) Allograft valve banking: techniques and technology. In: Hopkins RA (ed) Cardiac reconstructions with allograft valves. Springer, New York Berlin Heidelberg, pp 37–63

    Chapter  Google Scholar 

  • Lansing AM et al (1983) Left atrial-left ventricular bypass for congenital mitral stenosis. Ann Thorac Surg 35: 667–669

    Article  PubMed  CAS  Google Scholar 

  • Ledingham SJM et al. (1988) Bioprosthetic valve excision without replacement in the tricuspid position in a patient with Libman-Sacks endocarditis. J Cardiovasc Surg 29: 356–359

    CAS  Google Scholar 

  • Lentz DJ et al. (1982) Inhibition of mineralization of glutaraldehyde-fixed Hancock bioprosthetic heart valves. In Cohn LH, Gallucci V (eds) Cardiac bioprostheses. Yorke Medical, New York, p 306

    Google Scholar 

  • Levy RJ et al. (1987) Prevention of leaflet calcification of bioprosthetic heart valves with diphosphonate injection therapy. J Thorac Cardiovasc Surg 94: 551–557

    PubMed  CAS  Google Scholar 

  • Liotta D et al. (1978) Experiencia clinica conjunta con bioprotesis de bajio perfil. 6 congresso nacional de cirurgia cardiaca. Guaruja, Sao Paulo, Brazil

    Google Scholar 

  • Louis IS et al. (1991) Effects of warm ischemia following harvesting of allograft cardiac valves. Eur J Cardiothorac Surg 5: 458–465

    Article  Google Scholar 

  • Lurie AJ et al. (1977) Hemodynamic assessment of the glutaraldehyde preseved porcine heterograft in the aortic and mitral positions. Circulation 56 (Suppl II) 104–110

    Google Scholar 

  • Lytle BW et al. (1989) Primary isolated aortic valve replacement. J Thorac cardiovasc Surg 97: 675–694

    PubMed  CAS  Google Scholar 

  • Magilligan DJ (1987) Porcine bioprostheses in Cardiac surgery. In: Crawford TA (ed) current heart valve Prostheses state of the art reviews, vol 1, no 2. Hanley & Belfus, INC. Philadelphia, pp 269–284

    Google Scholar 

  • Magilligan DJ et al. (1983) Fate of a second porcine bioprosthetic valve. J Thorac Cardiovasc Surg 85: 362–370

    PubMed  Google Scholar 

  • Magilligan DJ et al. (1985) The porcine bioprosthesis valve: twelve years later. J Thorac Cardiovasc Surg 89: 499–507

    PubMed  Google Scholar 

  • Magilligan DJ et al (1989) The porcine bioprosthetic heart valve: experience at 15 years. Ann Thorac Surg 48: 324–330

    Article  PubMed  Google Scholar 

  • Mair R et al. (1993) Aortenklappenersatz mit kryokonservierten Pulmonalklappenallografts. Thorac Cardiovasc Surg 40 (in press)

    Google Scholar 

  • Marshall WG et al (1983) Late results after mitral valve replacement with the Björk-Shiley and porcine prostheses. J Thorac Cardiovasc Surg 85: 902–910

    PubMed  Google Scholar 

  • McGiffin DC et al. (1988) Longterm results of the viable cryopreserved allograft aortic valve: continuing evidence for superior valve durability. J Cardiac Surg 3 (Suppl): 289–296

    CAS  Google Scholar 

  • McGoon MD et al. (1984) Aortic and mitral valve incompetence: long-term follow-up (10 to 19 years) of patients treated with the Starr-Edwards prosthesis. J Am Coll Cardiol 3: 930

    Article  PubMed  CAS  Google Scholar 

  • McGregor CGA et al (1976) Tissue culture, protein and collagen synthesis in antibiotic sterilized canine heart valves. Cardiovasc Res 10: 389–395

    Article  PubMed  CAS  Google Scholar 

  • Menarche P et al. (1986) Selective blockade of collagen calcium binding sites: new process to decrease bioprosthetic valvular calcification. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical, New York, p 478

    Google Scholar 

  • Milano AD et al. (1988) Performance of the Hancock porcine bioprosthesis following aortic valve replacement: considerations based on a 15-year experience. Ann Thorac Surg 46: 216–222

    Article  PubMed  CAS  Google Scholar 

  • Milano AD et al. (1989) Aortic valve replacement with the Hancock standard, Björh-Shiley, and LiIlehei-Kaster prostheses. J Thorac Cardiovasc Surg 98: 37–47

    PubMed  CAS  Google Scholar 

  • Miller DC, Shumway NE (1987) “Fresh” aortic allografts: longterm results with freehand aortic valve replacement. J Cardiac Surg 2 (Suppl): 185–191

    CAS  Google Scholar 

  • Miller DC et al. (1982) Durability of porcine xenograft valves and conduits in children. Circulation 66 (Suppl I): 172

    Google Scholar 

  • Miller DC et al. (1987) Ten year clinical experience in 1681 patients with one type of tissue valve. In: Starek PJK (ed) Heart valve replacement and reconstruction. Year Book, Chicago

    Google Scholar 

  • Mitchell RS et al. (1986) Significant patient related determinants of prosthetic valve performance. J Thorac Cardiovasc Surg 91: 807–817

    PubMed  CAS  Google Scholar 

  • Morgan RJ, Davis JT, Fraker TD et al. (1985) Current status of valve prostheses. Surg Clin North Am 65: 699–720

    PubMed  CAS  Google Scholar 

  • Murray G (1956) Homologous aortic valve segments transplants. A surgical treatment for aortic and mitral insufficiency. Angiology 7: 466–471

    Article  PubMed  CAS  Google Scholar 

  • Myers Tt et al. (1978) Hemolytic anemia associated with heterograft replacement of the mitral valve. J Thorac Cardiovasc Surg 76: 214–215

    PubMed  CAS  Google Scholar 

  • Nistal Fetal. (1986) Primary tissue valve degeneration in glutaraldehyde-preserved porcine bioprostheses: Hancock I vs. Carpentier-Edwards at 4- to 7-year follow-up. Ann Thorac Surg 42: 568–572

    Article  Google Scholar 

  • Nudelman I et al (1980) Repeated mitral valve replacement in the growing child with congenital mitral valve disease. J Thorac Cardiovasc Surg 79: 765–769

    PubMed  CAS  Google Scholar 

  • Nunez L et al. (1982) Aspirin or coumadin as the drug of choice for valve replacement with porcine bioprosthesis. Ann Thorac Surg 33: 354–358

    Article  PubMed  CAS  Google Scholar 

  • Nunez L et al (1983) Pregnancy in 20 patients with bioprosthetic valve replacement. Chest 84: 26–28

    Article  PubMed  CAS  Google Scholar 

  • Nunez L et al. (1984) Prevention of thromboembolism using aspirin after mitral valve replacement with porcine bioprosthesis. Ann Thorac Surg 37: 84–87

    Article  PubMed  CAS  Google Scholar 

  • O’Brien MF et al (1987a) A comparison of aortic valve replacement with viable cryopreserved and fresh allograft valves, with a note on chromosomal studies. J Thorac Cardiovasc Surg 94: 812–823

    PubMed  Google Scholar 

  • O’Brien MF et al. (1987b) The viable cryopreserved allograft aortic valve. J Cardiac Surg 2 (Suppl): 153–167

    Google Scholar 

  • O’Brien MF et al. (1988) A study of the cells in the explanted viable cryopreserved allograft valve. J Cardiac Surg 3 (Suppl): 279–287

    Google Scholar 

  • O’Brien MF et al. (1991) Allograft aortic valve replacement: longterm comparative clinical analysis of the viable cryopreserved and antibiotic 4°C stored valves. J Cardiac Surg 6 (Suppl): 534–543

    Google Scholar 

  • Oyer PE et al. (1979) Long-term evaluation of the porcine xenograft bioprostheses. J Thorac Cardiovasc Surg 78: 343–350

    PubMed  CAS  Google Scholar 

  • Oyer PE et al. (1984) Thromboembolic risk and durability of the Hancock bioprosthetic cardiac valve. Eur Heart J 5 (Suppl D): 81

    PubMed  Google Scholar 

  • Pansini G et al (1990) Morphological comparison of primary tissue failure in porcine mitral and aortic bioprostheses in the same patient. Eur J Cardiothorac Surg 4: 431–434

    Article  PubMed  CAS  Google Scholar 

  • Pass HI et al (1984) Cardiac valve prostheses in children without anticoagulation. J Thorac Cardiovasc Surg 87: 832–835

    PubMed  CAS  Google Scholar 

  • Pelletier LC et al. (1989) Porcine vs. pericardial bioprostheses: a comparison of late results in 1593 patients. Ann Thorac Surg 47: 352–361

    Article  PubMed  CAS  Google Scholar 

  • Perier Pet al. (1986) Decreasing operative risk in isolated valve re-replacement. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical, New York, pp 333–338

    Google Scholar 

  • Perier P et al. (1989) A 10-year comparison of mitral valve replacement with Carpentier-Edwards and Hancock porcine bioprostheses. Ann Thorac Surg 48: 54–59

    Article  PubMed  CAS  Google Scholar 

  • Reul GJ et al. (1985) Valve failure with the Ionescu-Shiley bovine pericardial bioprosthesis: analysis of 2680 patients. J Vasc Surg 2: 192–204

    PubMed  Google Scholar 

  • Rhodes GR, McIntosh CL (1977) Evaluation of hemolysis following replacement of atrioventricular valves with porcine xenograft ( Hancock) valves. J Thorac Cardiovasc Surg 73: 312–315

    PubMed  CAS  Google Scholar 

  • Ross DN (1962) Homograft replacement of the aortic valve. Lancet II: 487

    Article  Google Scholar 

  • Ross D (1987) Panel discussion II. J Cardiac Surg 2 (Suppl): 222

    Google Scholar 

  • Ross D (1988) Pulmonary valve autotransplantation (the Ross operation). J Cardiac Surg 3: 313–319

    CAS  Google Scholar 

  • Ross D (1991) Technique of aortic valve replacement with a homograft: orthotopic replacement. Ann Thorac Surg 52: 154–156

    Article  PubMed  CAS  Google Scholar 

  • Ross DN, Shabbo FP, Wain WH et al. (1979) Longterm results of double valve replacement with aortic homografts. In: Sebening F, Klövekom WP, Meisner H, Struck E (eds) Bioprosthetic cardiac valves. Deutsches Herzzentrum Munich, printed by Eberl GmbtH, Immenstadt/Allgäu, pp 143–151

    Google Scholar 

  • Rossiter Si et al. (1978) Prosthetic valve endocarditis. Comparison of heterograft tissue valves and mechanical valves. J Thorac Cardiovasc Surg 76: 795–803

    PubMed  CAS  Google Scholar 

  • Rothlin et al. (1977) Langzeitverlauf nach Aorten-und Mitralklappenersatz. Herz 2: 268

    Google Scholar 

  • Rygg JH, Ladefoged J, Grgensen K, Elling F et al. (1986) Prevention of protein insudation and the related exterioration of bioprosthetic materials by incorporation of heparin-protein coupler. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical, New York, pp. 462–478

    Google Scholar 

  • Sanders SP et al. (1990) Use of Hancock porcine xenografts in children and adolescents. Am J Cardiol 46: 429–438

    Article  Google Scholar 

  • Schachner A et al. (1984) Prosthetic valve replacement in infants and children. J Cardiovasc Surg 25: 537–544

    CAS  Google Scholar 

  • Schaff HV et al. (1984) Late results after Starr-Edwards valve replacement in children. J Thorac Cardiovasc Surg 88: 583–589

    PubMed  CAS  Google Scholar 

  • Schoen FJ et al. (1983) Long-term failure rate and morphologic correlations in porcine bioprosthetic heart valves. Am J Cardiol 51: 957–64

    Article  PubMed  CAS  Google Scholar 

  • Schoen FJ et al. (1984) Bioprosthetic heart valve failure: pathology and pathogenesis. Cardiol Clin 2: 717–39

    PubMed  CAS  Google Scholar 

  • Schryer RI et al. Tomasek ER, Starr JA, Wright JTM (1986) Anticalcification effect of glutaraldehydepreserved valve tissue stored for increasing time in glutaraldehyde. In: Bodnar E, Yacoub M (eds) Biologic and bioprosthetic valves. Yorke Medical, New York, pp 471–477

    Google Scholar 

  • Senning A, Turina M (1972) Aortic valve replacement with free fascia lata grafts. Clinical experience and late evaluation of 141 consecutive cases. In: Ionescu MI, et al. (eds) Biological tissue in heart valve replacement. Butterworths, London

    Google Scholar 

  • Silver MM et al. (1980) Calcification in porcine xenograft valves in Children. Am J Cardiol 45: 685

    Article  PubMed  CAS  Google Scholar 

  • Spital G et al. (1992) Aortenklappenersatz mit Pulmonalisallograft–Perioperative Komplikationen im Vergleich mit Kunstklappen. Z Herz-Thorax-Gefäßchirurgie 6: 17–21

    Google Scholar 

  • Stein PD et al. (1985) Effect of warfarin on calcification of spontaneously degenerated porcine bioprosthetic valves. J Thorac Cardiovasc Surg 90: 119–125

    PubMed  CAS  Google Scholar 

  • Stelzer P, Elkins C (1989) Homograft valves and conduits: applications in cardiac surgery. Curr Probl Surg 26: 381–452

    Article  PubMed  CAS  Google Scholar 

  • Stinson EB et al. (1977) Long-term experience with porcine aortic valve xenografts. J Thorac Cardiovasc Surg 73: 54–63

    PubMed  CAS  Google Scholar 

  • Teoh KH et al. (1990) Clinical and Doppler echocardiographic evaluation of bioprosthetic valve failure after 10 years. Circulation 82 (Suppl IV): 110–116

    Google Scholar 

  • Teply JF et al. (1981) The ultimate prognosis after valve replacement: an assessment at twenty years. Ann Thorac Surg 32: 111–119

    Article  PubMed  CAS  Google Scholar 

  • Thandroyen FT et al. (1980) Severe calcification of glutaraldehyde-preserved porcine xenografts in children. Am J Cardiol 45: 690–696

    Article  PubMed  CAS  Google Scholar 

  • Thubrikar MJ et al. (1986) Patterns of calcific deposits in operatively excised stenotic or purely regurgitant aortic valves and their relation to mechanical stress. Am J Cardiol 58: 304–308

    Article  PubMed  CAS  Google Scholar 

  • Valente M et al. (1985) Ultrastructural substrates of dystrophic calcification in porcine bioprosthetic valve failure. Am J Pathol 119: 12–21

    PubMed  CAS  Google Scholar 

  • Van der Kamp AWM, Nauter J (1979) Fibroblast function and maintenance of aortic valve matrix. Cardiovasc Res 13: 167–173

    Article  PubMed  Google Scholar 

  • Van der Kamp AWM et al. (1981) Preservation of aortic heart valves with maintenance of cell viability. J Surg Res 30: 47–56

    Article  PubMed  Google Scholar 

  • Vejlsted H et al. (1984) Clinical experience with porcine xenografts in the mitral position. Scand J Thorac Cardiovasc Surg 18: 33

    Article  PubMed  CAS  Google Scholar 

  • Warnes CA et al. (1983) Comparison of late degenerative changes in porcine bioprostheses in mitral and aortic valve position in the same patient. Am J Cardiol 51: 965–968

    Article  PubMed  CAS  Google Scholar 

  • Wideman FE et al. (1981) The hospital mortality of re-replacement of the aortic valve. Incremental risk factors. J Thorac Cardiovasc Surg 82: 692–698

    PubMed  CAS  Google Scholar 

  • Wild LM et al. (1980) Left ventricular laceration due to stented prosthesis. Chest 77: 216–217

    Article  PubMed  CAS  Google Scholar 

  • Williams DB et al. (1982) Porcine heterograft valve replacement in children. J Thorac Cardiovasc Surg 84: 446–450

    PubMed  CAS  Google Scholar 

  • Woo YR et al. (1986) In vitro fluid dynamic characteristics of aortic bioprostheses: old versus new. Life Support Systems 4: 63

    PubMed  CAS  Google Scholar 

  • Wright JS et al. (1981) Mitral valve bypass by valved conduit. Ann thorac Surg 32: 294–296

    Article  PubMed  CAS  Google Scholar 

  • Wright JTM (1979) Hydrodynamic evaluation of tissue heart valves. In: Ionescu MI (ed) Tissue heart valves. Butterworths, London, p 55

    Google Scholar 

  • Wright JTM et al. (1982) Hancock II–an improved bioprosthesis. In: Cohn LH, Gallucci V (eds) Cardiac bioprostheses: proceedings of the second international symposium. Yorke Medical, New York, pp 425–444

    Google Scholar 

  • Yankah C, Hetzer R (1989) Valve selection and choice in surgery of endocarditis. J Cardiac Surg 4: 324–330

    Article  CAS  Google Scholar 

  • Yankah AC et al. (1986) Identification of surface antigens of endothelial cells of fresh preserved heart allografts. Thorac Cardiovasc Surg 34 (Special Issue I): 97

    Google Scholar 

  • Yankah AC et al. (1987) Transplantation of aortic and pulmonary allografts enhanced viability of endothelial cells by cryopreservation, importance of histocompatiblity. J Cardiac Surg 2 (Suppl): 209–220

    CAS  Google Scholar 

  • Zusman DR et al. (1981) Hemodynamic and clinical evaluation of the Hancock modified orifice bioprosthesis. Circulation 64 (Suppl II): 189

    Google Scholar 

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Scheld, H.H., Konertz, W. (1994). The Pathology of Bioprosthetic Heart Valves and Allografts. In: Berry, C. (eds) The Pathology of Devices. Current Topics in Pathology, vol 86. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76846-0_3

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