Abstract
Most acutely transforming leukemogenic or sarcomagenic retroviruses have transduced in their genomes altered cellular genes named oncogenes [1]. These viruses are usually defective in replication as a result of the deletion of structural genes, and they require a helper virus for propagation. Isolation of new acutely transforming retroviruses, comprehensive studies of their physiopathological processes, and molecular analysis of their genomes remain, therefore, powerful means for the identification of key genes involved in the regulation of cell growth, differentiation, or development.
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© 1992 Springer-Verlag Berlin Heidelberg
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Wendling, F., Souyri, M., Vigon, I., Gisselbrecht, S., Tambourin, P. (1992). The Molecular Biology of the Myeloproliferative Leukemia Virus. In: Neth, R., Frolova, E., Gallo, R.C., Greaves, M.F., Afanasiev, B.V., Elstner, E. (eds) Modern Trends in Human Leukemia IX. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76829-3_32
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DOI: https://doi.org/10.1007/978-3-642-76829-3_32
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