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Pathophysiology of Shock, Sepsis, and Organ Failure pp 593–608Cite as

Cytokine Modulation of Glucose Metabolism

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Abstract

Cellular elements of the immune system orchestrate the host-defense response against invading microorganisms through the production of an array of protein mediators, called cytokines. In this process, cytokines not only direct leukocytic elements against infectious agents, but also modulate the cardiovascular and metabolic response to infection. Generally, the immune response benefits the host’s overall fight against foreign invaders, but as a positive feedback system it can be detrimental to host survival under severe conditions.

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Authors and Affiliations

  1. Department of Physiology, Louisiana State University Medical Center, New Orleans, LA, 70112, USA

    G. J. Bagby, C. H. Lang & J. J. Spitzer

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  1. G. J. Bagby
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  2. C. H. Lang
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  3. J. J. Spitzer
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  1. Ludwig-Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstraße 13, A-1200, Vienna, Austria

    Günther Schlag M. D.  & Heinz Redl Ph. D.  & 

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Bagby, G.J., Lang, C.H., Spitzer, J.J. (1993). Cytokine Modulation of Glucose Metabolism. In: Schlag, G., Redl, H. (eds) Pathophysiology of Shock, Sepsis, and Organ Failure. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76736-4_43

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