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Introduction: “Organ in Shock”, “Early Organ Failure”, “Late Organ Failure”

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Pathophysiology of Shock, Sepsis, and Organ Failure

Abstract

The pathophysiology of traumatic shock, like that of severe intraoperative stress, is closely related to the development of a systemic inflammatory response syndrome (SIRS), which can lead to a subsequent organ dysfunction syndrome, which in turn can finally result in a multiorgan dysfunction syndrome (MODS) [1].

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References

  1. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RMH, Sibbald WJ (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101:1644–1655.

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  2. Redl H, Schlag G (1991) Pathophysiology of multiorgan failure — inflammatory factors and mediators. Clin Intensive Care 2:16–27.

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  3. Schlag R, Redl H, Dinges HP, Davies J (1991) Sources of endotoxin in the posttraumatic setting. In: Levin J, Sturk A, ten Cate J (eds) Bacterial endotoxins: cytokine mediators and new therapies for sepsis. Wiley/Liss, New York, pp 121–134.

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© 1993 Springer-Verlag Berlin Heidelberg

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Schlag, G., Redl, H. (1993). Introduction: “Organ in Shock”, “Early Organ Failure”, “Late Organ Failure”. In: Schlag, G., Redl, H. (eds) Pathophysiology of Shock, Sepsis, and Organ Failure. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76736-4_1

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  • DOI: https://doi.org/10.1007/978-3-642-76736-4_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76738-8

  • Online ISBN: 978-3-642-76736-4

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