Abstract
The rodent Harderian glands (HG) are large tubuloalveolar glands which occupy a considerable portion of the posterior half of the orbital cavity, and their secretions are vented by means of merocrine mechanisms (Sakai 1981). Although the function of this gland is poorly understood, its lipid-containing secretions may lubricate the nictitating membrane in those animals with a third eyelid (Davis 1929).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abreu P, Santana C, Hernandez G, Calzadilla CH, Alönso R (1987) Day-night rhythm of rat pineal tyrosine hydroxylase activity as determined by HPLC with amperometric detection. J Neurochem 48:665–668
Abreu P, Hernandez G, Hernandez CH, Alonso R (1988) Reproductive hormones control striatal tyrosine hydroxylase activity in the male rat. Neurosci Lett 95:213–217
Bradford MM (1976) A rapid and sensitive method for the quantitation of quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254
Bucana CD, Nadakavukaren MJ (1972) Innervation of the hamster Harderian gland. Science 175:205–206
Buzzell GR, Menéndez-Pelaez A, Porkka-Heiskanen T, Pangerl A, Pangerl B, Vaughan MK, Reiter RJ (1989) Bromocriptine prevents the castration-induced rise in porphyrin concentration in the Harderian glands of the male Syrian hamster, Mesocricetus auratus. J Exp Zool 249:172–176
Cardinali DP, Romeo HE, Vacas MI (1987) Neuroendocrine projections of superior cervical ganglia. In: Reiter RJ, Fraschini F (eds) Advances in pineal research, vol 2. John Libbey, London, pp 35–49
Davis FA (1929) The anatomy and histology of the eye and orbit of the rabbit. Trans Am Ophthalmol Soc 27:401–441
Hamil RW, Earley CJ, Guernseyl LA (1984) Hormonal regulation of adult sympathetic neurons: the effects of castration on tyrosine hydroxylase activity. Brain Res 299:331–337
Hernández G, Abreu P, Alonso R, Santana C, Moujir F, Calzadilla CH (1991) Castration reduces the nocturnal rise of pineal melatonin levels in the male rat by impairing its noradrenergic input. J Neuroendocrinol (in press)
Hoffman RA, Johnson LB, Reiter RJ (1985) Harderian glands of golden hamsters: temporal and sexual differences in immunoreactive melatonin. J Pineal Res 2:161–168
Hoffman RA, Johnson LB, Reiter RJ (1989a) Regulation of melatonin in the Harderian glands of golden hamsters. J Pineal Res 6:63–71
Hoffman RA, Vaughan MK, Reiter RJ (1989b) Photic input and pineal-Harderian-thyroid gland interactions in golden hamsters. In: Reiter RJ, Pang SF (eds) Advances in pineal research, vol 3. John Libbey, London, pp 225–230
Huhtala A, Huikuri KT, Palkama A, Tervo T (1977) Innervation of the rat Harderian gland by adrenergic and cholinergic nerve fibers. Anat Rec 188:263–272
Menéndez-Pelaez A, Reiter RJ, Guerrero JM, Puig-Domingo M, Howes KA (1988a) Sexual dimorphism in N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity and melatonin content in the Harderian gland of Syrian hamsters: changes following gonadectomy. Proc Soc Exp Biol Med 187:287–291
Menéndez-Pelaez A, Reiter RJ, Howes KA, Puig-Domingo M, Vaughan MK, Troiani ME, Little JC (1988b) Harderian gland N-acetyltransferase activity in the male Syrian hamster: effects of gonadectomy, short photoperiod exposure, or subcutaneous melatonin implants. Endocr Res 14:121–130
Menéndez-Pelaez A, Santana C, Howes KA, Sabry I, Reiter RJ (1988c) Effects of photoperiod or exogenous melatonin administration on the activity of N-acetyltransferase and hydroxyindole-O-methyltransferase and the melatonin content of the Harderian gland of two strains of female Syrian hamster. J Pineal Res 5:293–300
Menéndez-Pelaez A, Reiter RJ, Guerrero JM, Santana C, Howes KA, Gonzâlez-Brito A (1988d) N-acetyltransferase activity and melatonin concentrations in the Harderian glands of female Syrian hamsters: alterations following either pinealectomy or bilateral superior cervical gan-glionectomy. Biochem Arch 4:231–238
Menéndez-Pelaez A, Reiter RJ, Gonzâlez-Brito A, Howes KA, (1989a) N-acetyltransferase activity and indole contents of the male Syrian hamster Harderian gland: changes during the lightdark cycle. Arch Biochem Biophys 268:20–25
Menéndez-Pelaez A, Reiter RJ, Gonzâlez-Brito A, Santana C, Guerrero JM (1989b) Regulation of N-acetyltransferase in the Syrian hamster Harderian glands. In: Reiter RJ, Pang SF (eds) Advances in pineal research, vol 3. John Libbey, London, pp 77–81
Norvell JE, Clabough JW (1972) Adrenergic and cholinergic innervation of the hamster Harderian gland. Science 178:1102–1103
Pangerl A, Pangerl B, Buzzell GR, Jones DJ, Reiter RJ (1989a) Characterization of B-adrenoceptors in the Syrian hamster Harderian gland: sexual differences and effects of either castration or superior cervical ganglionectomy. J Neurosci Res 22:456–460
Pangerl A, Pangerl B, Jones DJ, Reiter RJ (1989b) B-adrenoceptors in the extraorbital lacrimal gland of the Syrian hamster. Characterization with I-iodopindolol and evidence of sexual dimorphism. J Neural Transm 77:153–162
Puig-Domingo M, Guerrero JM, Reiter RJ, Peinado MA, Sabry I, Viader M, Webb SM (1988a) Identification of immunoreactive somatostatin in the rat Harderian gland: regulation of its content by growth hormone, beta-adrenergic agonists and calcium channel blockers. Peptides 9:571–574
Puig-Domingo M, Guerrero JM, Reiter RJ, Peinado MA, Menéndez-Pelaez A, Santana C, Webb SM (1988b) Androgenic control of immunoreactive somatostatin in the Harderian gland of the Syrian hamster. J Reprod Fertil 82:753–759
Sakai T (1981) The mammalian Harderian gland: morophology, biochemistry, function and phylogeny. Arch Histol Jpn 44:299–333
Södersten P, Eneroth P, Pettersson A (1983) Episodic secretion of luteinizing hormone and androgen in male rats. J Endocrinol 97:145–153
Tsukahara S, Jacobowitz DM (1987) Peptidergic innervation of the rat Harderian gland. Histochemistry 87:233–236
Uddman R, Alumets J, Ehinger B, Hakanson R, Lorén I, Sundler F (1980) Vasoactive intestinal peptide nerves in ocular and orbital structures of the cat. Invest Ophthalmol Visual Sci 19:878–885
van Jaarsveld A, Mhatre MC, Reiter RJ (1989) Porphyrine levels in the Harderian glands of female and male Syrian hamsters: early changes following either gonadectomy or light deprivation and lack of a circadian rhythm. Biomed Res 10:1–8
Vilchis F, Hernandez A, Pérez AE, Pérez-Palacios G (1987) Hormone regulation of the rodent Harderian gland: binding properties of the androgen receptor in the male golden hamster. J Endocrinol 112:3–8
Westerink BHC (1985) Sequence and significance of dopamine metabolism in the rat brain. Neurochem Int 7:221–227
Wright LL, Smolen AJ (1985) Effects of neonatal castration or treatment with dihydrotestosterone on number of neurons in the rat superior cervical sympathetic ganglion. Dev Brain Res 20:314–316
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Abreu, P., Hernández, G., Fajardo, N., Alonso, R. (1992). Adrenergic Activity in the Male Rat Harderian Gland. In: Webb, S.M., Hoffman, R.A., Puig-Domingo, M.L., Reiter, R.J. (eds) Harderian Glands. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76685-5_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-76685-5_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-76687-9
Online ISBN: 978-3-642-76685-5
eBook Packages: Springer Book Archive