Abstract
Most rats inoculated with lymphocytic choriomeningitis virus intracerebrally at birth do not develop external lesions, although in a few corneal leukoma may be seen 2 months after infection. Others develop iridocorneal adhesions within 10 months (del Cerro et al. 1982). Fun- duscopic examination reveals mottling of the retinal pigment epithelium, vascular attenuation, thinning of the retina, and retinal detachment with or without subretinal hemorrhage or exudate (del Cerro et al. 1982). Electroretino- graphic examination demonstrates a continual reduction in a- and b-wave response beginning by 2 months postinoculation and resulting in some eyes failing to respond by 10 months postinoculation (del Cerro et al. 1982).
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© 1991 Springer-Verlag Berlin Heidelberg
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Whiteley, H.E., Atherton, S.S., Shadduck, J.A. (1991). Lymphocytic Choriomeningitis Virus Infection, Experimental, Eye, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Eye and Ear. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76640-4_19
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DOI: https://doi.org/10.1007/978-3-642-76640-4_19
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