Abstract
This condition has not been well described in terms of gross appearance; generally, the process diffusely involves the fundus with retinal thinning with or without alteration of the underlying retinal pigment epithelium (more obvious in pigmented animals) and as such will appear as total or geographic areas of change in intensity of coloration.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Clark B, Johnson ML, Dreher RE (1946) The effect of sunlight on dark adaptation. Am J Ophthalmol 29: 828–836
Dawson WW, Herron WL (1970) Retinal illumination during indirect ophthalmoscopy: subsequent dark adaptation. Invest Ophthalmol Vis Sci 9: 89–96
Dowling JE, Sidman RL (1962) Inherited retinal dystrophy in the rat. J Cell Biol 14: 73–109
Dowling JE, Gibbons IR, Smelser GK (1961) The effect of vitamin A deficiency on the fine structure of the retina. In: Smelser GK (ed) The structure of the eye. Academic, New York, pp 85–99
Frank RN, Mancini MA (1986) Presumed retinovitreal neovascularization in dystrophic retinas of spontaneously hypertensive rats. Invest Ophthalmol Vis Sci 27: 346–355
Grignolo A, Orzalesi N, Castellazzo R, Vittone P (1969) Retinal damage by visible light in albino rats: an electron microscope study. Ophthalmologica 157: 43–59
Hansson HA (1970) Ultrastructural studies on rat retina damaged by visible light. Virchows Arch [B] 6: 247–262
Hecht S, Hendley CD, Ross S, Richmond PN (1948) The effect of exposure to sunlight on night vision. Am J Ophthalmol 31:1573–1580
Kuwabara T (1970) Retinal recovery from exposure to light. Am J Ophthalmol 70:187–198
Kuwabara T, Gorn RA (1968) Retinal damage by visible light: an electron microscope study. Arch Ophthalmol 79: 69–78
Lawwill T (1973) Effects of prolonged exposure of rabbit retina to low intensity light. Invest Ophthalmol Vis Sei 12: 45–51
La Vail MM (1980) Eye pigmentation and constant light damage in the rat retina. In: Williams TP, Baker BN (eds) The effects of constant light on visual processes. Plenum, New York, pp 357–387
La Vail MM, Gorrin GM, Repaci MA, Yasumura D (1987) Light induced retinal degeneration in albino mice and rats: strain and species differences. In: Prog Clin Biol Res 247: 439–454
Marshall J, Mellerio J, Palmer DA (1972) Damage to pigeon retinae by moderate illumination from fluorescent lamps. Exp Eye Res 14:164–169
Noell WK (1955) Metabolic injuries of the visual cell. Am J Ophthalmol 40: 60–68
Noell WK (1962) X-irradiation studies on mammalian retina. In: Haley TJ, Snider RS (eds) Response of the nervous system to ionizing radiation. Academic, New York, pp 543–559
Noell WK (1979) Effects of environmental lighting and dietary vitamin A on the vulnerability of the retina to light damage. Photochem Photobiol 29: 717–723
Noell WK (1980) Possible mechanisms of photoreceptor damage by light in mammalian eyes. Vision Res 20: 1163–1171
Noell WK, Albrecht R (1971) Irreversible effects of visible light on the retina: role of vitamin A. Science 172: 76–80
Noell WK, Walker VS, Kang BS, Berman S (1966) Retinal damage by light in rats. Invest Ophthalmol Vis Sci 5: 450–473
O’Steen WK (1970) Retinal and optic nerve serotonin and retinal degeneration as influenced by photoperiod. Exp Neurol 27:194–205
O’Steen WK (1977) Ovarian steroid effects on light induced retinal photoreceptor damage. Exp Eye Res 25: 361–369
O’Steen WK (1980) Hormonal influences on retinal photodamage. In: Williams TP, Baker BN (eds) The effects of constant light on visual processes. Plenum, New York, p 29
O’Steen WK, Donnelly JE (1982) Chronologic analysis of variations in retinal damage in two strains of rats after short-term illumination. Invest Ophthalmol Vis Sei 22: 252–255
O’Steen WK, Kraeer SL (1977) Effects of hypophysec- tomy, pituitary gland homogenates and transplants, and prolactin on photoreceptor destruction. Invest Ophthalmol Vis Sei 16: 940
O’Steen WK, Lytle RB (1971) Early cellular disruption and phagocytosis in photically-induced retinal degeneration. Am J Anat 130: 227–234
O’Steen WK, Shear CR, Anderson KV (1972) Retinal damage after prolonged exposure to visible light: a light and electron microscope study. Am J Anat 139: 5–22
O’Steen WK, Anderson KV, Shear CR (1974) Photoreceptor degeneration in albino rats: dependency on age. Invest Ophthalmol Vis Sci 13: 334–339
Penn JS, Howard AG, Williams TP (1985) Light damage as a function of “light history” in the albino rat. In: La- Vail MM, Hollyfield JG, Anderson RE (eds) Retinal degeneration: experimental and clinical studies. Liss, New York, pp 439–447
Radnot M, Jabbâgy P, Heszberger I, Lovas B (1969) Les donées à l’ultrastructure de la rétine humanine sous l’effet de la lumière. Ophthalmologica 159: 460–471
Rapp LM, Williams TP (1980) A parametric study of retinal light damage in albino and pigmented rats. In: Williams TP, Baker BN (eds) The effects of constant light on visual processes. Plenum, New York, pp 135–159
Saunders LZ (1975) Ophthalmic pathology of animals. Karger, Basel
Williams TP, Howell WL (1983) Action spectrum of retinal light damage in albino rats. Invest Ophthalmol Vis Sei 24: 285–287
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Peiffer, R.L., Porter, D.P. (1991). Light-Induced Retinal Degeneration, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Eye and Ear. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76640-4_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-76640-4_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-76642-8
Online ISBN: 978-3-642-76640-4
eBook Packages: Springer Book Archive