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Radiation-Induced Cataracts, Mouse and Rat

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Eye and Ear

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Cataracts in general, including radiation cataracts, are difficult to diagnose grossly in fixed specimens due to inability to distinguish lesions from lens fixation artifact. With intumescent cataracts the lens will be swollen; with hypermaturehypermature cataracts the lens will be shrunken with capsular wrinkling. Calcification and fibrous metaplasia will appear as localized white densities. In general, all forms of ionizing radiation give rise to cataracts that are similar in appearance, both clinically (as viewed with the slit-lamp biomicroscope) and histologically.

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© 1991 Springer-Verlag Berlin Heidelberg

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Peiffer, R.L. (1991). Radiation-Induced Cataracts, Mouse and Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Eye and Ear. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76640-4_14

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  • DOI: https://doi.org/10.1007/978-3-642-76640-4_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76642-8

  • Online ISBN: 978-3-642-76640-4

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