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Engraftment-Promoting Potential of High-Dose Cytostatic Agents in Allogeneic Bone Marrow Transplantation

  • Conference paper
Acute Leukemias

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 34))

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Abstract

Graft rejection is a serious problem in HLA-mismatched and in T-cell-depleted HLA-identical bone marrow transplantation. Rejection rates of up to 35% have been observed in cases where HLA-identical hone marrow depleted of T lymphocytes was grafted following conventional conditioning with cyclophosphamide and total body irradiation [1].

Supported by a grant from Heinz and Gudrun Bauer, Hamburg/FRG, in memoriam of their son Hendrik.

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Authors and Affiliations

  1. Second Department of Internal Medicine and Department of Immunology, University of Kiel, Chemnitzstraße 53-57, 2300, Kiel, Germany

    B. Glass, W. Gassmann, L. Uharek, A. Erbersdobler, H. Loeffler & W. Mueller-Ruchholtz

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  1. B. Glass
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  2. W. Gassmann
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  3. L. Uharek
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  4. A. Erbersdobler
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  5. H. Loeffler
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  6. W. Mueller-Ruchholtz
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, University of Münster, Albert-Schweitzer-Straße 33, D-4400, Münster, Federal Republic of Germany

    W. Hiddemann , T. Büchner  & B. Wörmann ,  & 

  2. M. D. Anderson Cancer Center, University of Texas, 1515 Holocombe Boulevard, 77030, Houston, TX, USA

    W. Plunkett , M. Keating  & M. Andreeff ,  & 

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© 1992 Springer-Verlag Berlin Heidelberg

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Glass, B., Gassmann, W., Uharek, L., Erbersdobler, A., Loeffler, H., Mueller-Ruchholtz, W. (1992). Engraftment-Promoting Potential of High-Dose Cytostatic Agents in Allogeneic Bone Marrow Transplantation. In: Hiddemann, W., Büchner, T., Wörmann, B., Plunkett, W., Keating, M., Andreeff, M. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 34. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76591-9_91

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  • DOI: https://doi.org/10.1007/978-3-642-76591-9_91

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53949-0

  • Online ISBN: 978-3-642-76591-9

  • eBook Packages: Springer Book Archive

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