Abstract
The arterial baroreceptor reflexes act to maintain arterial pressure constant at a set point or operating point. The operating point is determined by the mean arterial pressure and by the arterial pulse pressure. In resting man or resting experimental animals, it is the pressure when there are no obvious internal or external stresses or perturbations which might alter the pressure. The set point may vary with state, as in exercise or rest, or with emotional stress. Over the short term, the reflex operates to minimize changes from the set point which might occur with such stresses as blood loss or positional changes. The set point appears to be altered during exercise, but newer information indicates that the reflex functions much as it does at rest [169]. (See also the review by Ludbrook [133] and the chapter by Joyner and Shepherd in this volume.) Loss of these reflexes impairs or may even destroy the ability to respond properly to some external stimuli or to disease states. (See chapter on heart failure by Thames and Dibner-Dunlap in this volume.)
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Literatur
Abboud FM, Thames MD (1983) Interaction of cardiovascular reflexes in circulatory control. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 675–753 (Handbook of Physiology, Sect 2, vol III, part 2 )
Adams WE (1958) The comparative morphology of the carotid body and carotid sinus. Thomas, Springfield, pp 1–259
Alexander RS (946) Tonic and reflex functions of medullary sympathetic cardiovascular centers. J Neurophysiol 9:205–217
Allison JL, Sagawa K, Kumada M (1969) An open-loop analysis of the aortic arch barostatic reflex. Am J Physiol 217: 1576–1584
Andresen MC, Yang M (1989) Interaction among unitary spike trains: implications for whole nerve measurements. Am J Physiol 256: R997–1004
Angell-James JE, Daly M de B (1970) Comparison of the reflex vasomotor responses to separate and combined stimulation of the carotid sinus and aortic arch baroreceptors by pulsatile and non-pulsatile pressure in the dog. J Physiol (Lond) 209: 257–293
Angell-James JE, Daly M de B (1971) Effects of graded pulsatile pressure on the reflex vasomotor responses elicited by changes of mean pressure in the perfused carotid sinus-aortic arch regions of the dog. J Physiol (Lond) 214: 51–61
Angell-James JE, George MJ (1980) Carotid sinus baroreceptor reflex control of the circulation in medial sclerotic and renal hypertensive rabbits and its modification by the aortic baroreceptors. Circ Res 47: 890–901
Arndt JO, Morgenstern J, Samodelov L (1977) The physiologically relevant information regarding systemic blood pressure encoded in the carotid sinus baroreceptor discharge pattern. J Physiol (Lond) 268: 775–791
Barman SM, Gebber GL (1980) Sympathetic nerve rhythm of brain stem origin. Am J Physiol 239: R42–R47
Barman SM, Gebber GL (1982) Hypothalamic neurons with activity patterns related to sympathetic nerve discharge. Am J Physiol 242: R34–R43
Beiser GD, Zelis R, Epstein SE, Mason DT, Braunwald E (1970) The role of skin and muscle resistance vessels in reflexes mediated by the baroreceptor system. J Clin Invest 49: 237–255
Bennett TD, Wyss CR, Scher AM (1984) Changes in vascular capacity in awake dogs in response to carotid sinus occlusion and administration of catecholamines. Circ Res 55: 440–453
Berger AJ (1979) Distribution of carotid sinus nerve afferent fibres to solitary tract nuclei of the cat using transganglionic transport of horseradish perioxidase. Neurosci Lett 145: 153–158
Bevan JA (1979) Some bases of differences in vascular response to sympathetic activity. Circ Res 45: 161–171
Bishop VS, Malliani A, Thoren P (1983) Cardiac mechanoreceptors. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 497–555 (Handbook of physiology, sect 2, vol III, part 2 )
Blomberry PA, Körner PI (1979) Relative contributions of aortic and carotid sinus baroreceptors to the baroreceptor-heart rate reflex of the conscious rabbit. J Auton Nerv Syst 1: 161–171
Blomqvist CG, Stone HL (1983) Cardiovascular adjustments to gravitational stress. In: Berne R (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 1025–1063 (Handbook of physiology, sect 2, vol III, part 2 )
Blumberg H, Janig W, Rieckmann C, Szulezyk P (1980) Baroreceptor and chemoreceptor reflexes in postganglionic neurons supplying skeletal muscle and hairy skin. J Auton Nerv Syst 2: 223–240
Boss J, Green JH (1956) The histology of the common carotid baroreceptor areas of the cat. Circ Res 4: 12–17
Braunwald E, Ross John Jr (1979) Control of cardiac performance. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 533–581 (Handbook of physiology, sect 2, vol
Bristow JD, Honour AJ, Pickering TG, Sleight P (1969) Cardiovascular and respiratory changes during sleep in normal and hypertensive subjects. Cardiovasc Res 3: 476–485
Bronk DW, Ferguson LK, Margaria R, Solandt DY (1936) The activity of the cardiac sympathetic centers. Am J Physiol 117: 237–249
Brooksby GA, Donald DE (1971) Dynamic changes in splanchnic blood flow and blood volume in dogs during activation of sympathetic nerves. Circ Res 29: 227–238
Brooksby GA, Donald DE (1972) Release of blood from the splanchnic circulation in dogs. Circ Res 31: 105–118
Brown AM (1979) Cardiac reflexes In: Berne RM (ed) The cardiovascular system. The heart. American Physiological Society, Bethesda, pp 677–689 (Handbook of physiology, sect 2, vol I)
Brown AM (1980) Receptors under pressure: an update on baroreceptors. Circ Res 46: 1–10
Brown AM, Saum WR, Tuley FH (1976) A comparison of aortic baroreceptor discharge in normotensive and spontaneously hypertensive rats. Circ Res 39: 488–496
Brunner MJ, Greene AS, Kallman CH, Shoukas A A (1984) Interaction of canine carotid sinus and aortic arch baroreflexes in the control of total peripheral resistance. Circ Res 55: 740–750
Brunner MJ, Greene AS, Frankle AE, Shoukas A A (1988) Carotid sinus baroreceptor control of splanchnic resistance and capacity. Am J Physiol 255: H1305–1310
Burattini R, Borgdorff P (1984) Closed-loop baroreflex control of total peripheral resistance in the cat: identification of gains by aid of a model. Cardovasc Res 18: 715–723
Burnstock G (1980) Cholinergic and purinergic regulation of blood vessels. In: Bohr DF, Somlyo AP, Sparks HV Jr (eds) The cardiovascular system. Vascular smooth muscle. American Physiological Society, Bethesda, pp 567–612 (Handbook of physiology, sect 2, vol I I )
Canon WB (1932) The wisdom of the body. Norton, New York
Carmeliet E, Vereecke J (1979) Electrogenesis of the action potential and automaticity. In: Berne RM (ed) The cardiovascular system. The heart, American Physiological Society, Bethesda, pp 269–334 (Handbook of physiology, sect 2, vol 1 )
Caraeiro JJ, Donald DE (1977) Change in liver blood flow and content in dogs during direct and reflex alteration of hepatic sympathetic nerve. Circ Res 40 (2): 150–158
Carneiro JJ, Donald DE (1977) Blood reservoir function of dog spleen, liver and intestine. Am J Physiol 232: H67–H72
Celander O (1954) The range of control exercised by the “sympathico-adrenal system”. Acta Physiol Scand [Suppl] 116: 1–132
Chen HI, Bishop VS (1983) Baroreflex open-loop gain and arterial pressure compensation in hemorrhagic hypotension. Am J Physiol 245: H54–H59
Chen HI, Chai CY, Tung CS, Chen HC (1979) Modulation of the carotid baroreflex function during volume expansion. Am J Physiol 237 (Heart Circ Physiol 6): H153–H158
Coleman TG (1980) Arterial baroreflex control of heart rate in the conscious rat. Am J Physiol 238 (Heart Circ Physiol 7): H515–H520
Cottle MK (1964) Degeneration studies of primary afferents of IXth and Xth cranial nerves in the cat. J Comp Neurol 122: 329–345
Cox RH, Bagshaw RJ (1980) Carotid sinus control of pulsatile hemodynamics in halothane-anesthetized dogs. Am J Physiol 239 (Heart Circ Physiol 7): H294–H299
De Castro F (1928) Sur la structure et l’innervation du sinus carotidien de l’Homme et des Mammiferes neuveaux faits sur l’innervation et la fonction du glomus caroticum. Etudes anatomiques et physiologiques. Trab Lab Invest Biol 25: 331–380
DeGeest H, Levy MN, Zieske H Jr (1964) Carotid sinus baroreceptor reflex effects upon myocardial contractility. Circ Res 15: 327–342
Delius W, Hagbarth KE, Hongell A, Wallin BG (1972) Maneuvers affecting sympathetic outflow in human skin nerves. Acta Physiol Scand 84: 177–186
Derbyshire DR, Smith G (1984) Sympathoadrenal responses to anesthesia and surgery. Br J Anaesth 56: 725–739
DiCarlo SE, Bishop VS (1988) Exercise training attenuates baroreflex regulation of nerve activity in rabbits. Am J Physiol 255 (Heart Circ Physiol 24): H974–H979
DiSalvo J, Parker PE, Scott JB, Haddy FJ (1971) Carotid baroreceptor influence on coronary vascular resistance in the anesthetized dog. Am J Physiol 221: 156–160
Donald DE (1981) Mobilization of blood from the splanchnic circulation. In: Lautt WW (ed) Hepatic circulation in health and disease. Raven, New York, pp 193–202
Donald DE, Edis AJ (1971) Comparison of aortic and carotid baroreceptor reflexes in the dog. J Physiol (Lond) 215: 521–538
Donald DE, Rowlands DJ, Ferguson D (1970) Similarity of blood flow in the normal and the sympathectomized dog hindlimb during graded exercise. Circ Res 26: 185–199
Donoghue S, Felder RB, Jordan D, Spyer KM (1984) The central projections of carotid baroreceptors and chemoreceptors in the cat: a neurophysiological study. J Physiol (Lond) 347: 397–409
Donoghue S, Garcia M, Jordan D, Spyer KM (1982) Identification and brainstem projections of aortic baroreceptor afferent neurones in nodose ganglia of cats and rabbits. J Physiol (Lond) 322: 337–352
Dorward PK, Riedel W, Burke SL, Gipps J, Korner PI (1985) The renal sympathetic baroreflex in the rabbit. Circ Res 57: 618–633
Downing SE (1980) Baroreceptor regulation of the heart. In: Berne RM (ed) The cardiovascular system. The Heart. American Physiological Society, Bethesda, pp 621–652 (Handbook of physiology, sect 2, vol I )
Downing SE, Siegel JH (1983) Baroreceptor and chemoreceptor influences on sympathetic discharge to the heart. Am J Physiol 204: 471–479
Eckberg DL, Nerhed C, Wallin BG (1985) Respiratory modulation of muscle sympathetic and vagal cardiac outflow in man. J Physiol (Lond) 365: 181–196
Eckberg DL, Rea RF, Andersson OK, Hedner T, Pernow J, Lundberg JM, Wallin BG (1988) Baroreflex modulation of sympathetic activity and sympathetic neurotransmitters in humans. Acta Physiol Scand 133: 221–231
Edholm OG, Fox RH, MacPherson RK (1957) Vasomotor control of the cutaneous blood vessels in the human forearm. J Physiol (Lond) 139: 455–465
Feigl EO (1968) Carotid sinus reflex control of coronary blood flow. Circ Res 23: 223–237
Feigl EO (1983) Coronary physiology. Physiol Rev 63: 1–205
Franz GN, Scher AM, Ito CS (1971) Small signal characteristics of carotid sinus baroreceptors of rabbits. J Appl Physiol 30: 527–535
Glick G (1971) Importance of the carotid sinus baroreceptors in the regulation of myocardial performance. J Clin Invest 50: 1116–1123
Green HD, Kepchar JH (1959) Control of peripheral resistance in major systemic vascular beds. Physiol Rev 39: 617–686
Greene AS, Brunner MJ, Shoukas AA (1986) Interaction of right and left carotid sinus baroreflexes in the dog. Am J Physiol 250 (Heart Circ Physiol 19): H96–H107
Greenfield ADM (1963) The circulation through the skin. In: Hamilton WF, Dow P (eds) Circulation. American Physiological Society, Washington DC, pp 1325–1351 (Handbook of physiology, sect 2, vol I I )
Gregor M, Janig W, Wiprich L (1977) Cardiac and respiratory rhythmicities in cutaneous and muscle vasoconstrictor neurones to the cat’s hindlimb. Pflugers Arch 370: 299–302
Hagbarth KE, Vallbo AB (1968) Pulse and respiratory grouping of sympathetic impulses in human muscle nerves. Acta Physiol Scand 84: 164–176
Hainsworth R, Karim F (1972) Inotropic responses of the left ventricle to changes in aortic arch pressure in anaesthetized dogs. J Physiol (Lond) 223: 213–228
Hainsworth R, Karim F (1973) Left ventricular inotropic and peripheral vasomotor responses from independent changes in pressure in the carotid sinuses and cerebral arteries in anesthetized dogs. J Physiol (Lond) 228: 139–155
Hainsworth R, Ledsome JR, Carswell F (1970) Reflex responses from aortic baroreceptors. Am J Physiol 218: 423–429
Head GA, McCarty R (1987) Vagal and sympathetic components of the heart rate range and gain of the baroreceptor-heart rate reflex in conscious rats. J Auton Nerv Syst 21: 203–213
Hebert MT, Marshall JM (1988) Direct observation of effects of baroreceptor stimulation on mesenteric circulation of the rat. J Physiol (Lond) 400: 29–44
Heistad DD, Abboud FM, Mark AL, Schmid PG (1973) Interaction of thermal and baroreflexes in man. J Appl Physiol 35: 581–586
Heymans C, Neil E (1958) Reflexogenic areas in the cardiovascular system. Churchill, London
Higgins CB, Vatner SF, Braunwald E (1973) Parasympathetic control of the heart. Pharmacol Rev 25: 119–155
Hilton SM (1965) Hypothalamic control of the cardiovascular responses in fear and rage. Sci Basis Med 217–238
Hintze T, Vatner SF (1982) Cardiac dynamics during hemorrhage: relative unimportance of adrenergic inotropic responses. Circ Res 50: 705–713
Hosomi H, Sagawa K (1979) Sinovagal interaction in arterial pressure restoration after 10% hemorrhage. Am J Physiol 237. R203–209
Hosomi H, Chatani H, Kaizuka T, Katsuda S, Hayashida Y (1983) Overall open-loop gain of rapidly acting arterial pressure control system in rabbits. Pflugers Arch 399: 134–138
Huang AH, Feigl EO (1988) Adrenergic coronary vasoconstriction to maintain uniform transmural blood flow distribution during exercise. Circ Res 62: 286–298
Humphrey DR (1967) Neuronal activity in the medulla oblongata of the cat evoked by stimulation of the carotid sinus nerve. In: Kezdi P (ed) Baroreceptors and hypertension. Pergamon, Oxford, pp 131–168
Iriuchijima J, Kumada M (1964) Activity of single vagal fibres efferent to the heart. Jpn J Physiol 14: 479–487
Iriuchijima J, Soulsby ME, Wilson MF (1968) Participation of cardiac sympathetics in carotid occlusion pressor reflex. Am J Physiol 215: 1111–1114
Ishikawa N, Sagawa K (1983) Nonlinear summation of depressor effects of carotid sinus pressure changes and aortic nerve stimulation in the rabbit. Circ Res 52: 401–410
Ito CS, Feigl EO (1985) Carotid baroreceptor reflex coronary vasodilation in the dog. Circ Res 56: 486–495
Janig W, Sundlof G, Wallin BG (1983) Discharge patterns of sympathetic neurons supplying skeletal muscle and skin in man and cat. J Auton Nerv Syst 7: 239–256
Jewett DL (1964) Activity of single efferent fibres in the cervical vagus nerve of the dog, with special reference to possible cardioinhibitory fibres. J Physiol (Lond) 175: 321–357
Johnson EA (1979) Force-interval relationship of cardiac muscle. In: Berne RM (ed) The cardiovascular system. The heart. American Physiological Society, Bethesda, pp 475–496 (Handbook of physiology sect 2, vol I )
Johnson JM, Niederberger, Rowell LB, Eisman MM, Brengelmann GL (1973) Competition between cutaneous vasodilator and vasoconstrictor reflexes in man. J Appl Physiol 35: 798–803
Johnson JM, Rowell LB, Niederberger M, Eisman MM (1974) Human splanchnic and forearm vasoconstrictor responses to reductions of right atrial and aortic pressure. Circ Res 34: 515–524
Johnson JM, Rowell LB, Brengelmann GL (1974) Modification of the skin blood flow-body temperature relationship by upright exercise. J Appl Physiol 37: 880–886
Joyner MJ, Lennon RL, Wedel DJ, Rose SH, Shepherd JT (1990) Blood flow to contracting human muscles: influence of increased sympathetic activity. J Appl Physiol 68: 1453–1457
Kaizuka T, Yoshida H, Hosomi H (1985) Time-dependent effect of sectioning carotid sinus nerves on the vagally mediated baroreflex. Pflugers Arch 403: 258–261
Kalkoff W (1957) Pressorezeptorische Aktionspotentiale und Blutdruckregulation. Verh Dtsch Ges Kreislaufforsch 23: 397–401 (K270)
Kass DA, Maughan WL, Guo ZM, Kono A, Sunagawa K, Sagawa K (1987) Comparative influence of load versus inotropic states on indexes of ventricular contractility: experimental and theoretical analysis based on pressure-volume relationships. Circulation 76: 1422–1436
Katona PG, Poitras JW, Pantelakis N, Jensen EW, Barnett GO (1988) Deterministic nature of baroreceptor firing. Am J Physiol 215: 1–7
Katona P, Poitras J, Barnett U, Terry B (1970) Cardiac vagal efferent activity and heart period in the carotid sinus reflex. Am J Physiol 218: 1030–1037
Kellogg DL Jr, Johnson JM, Kosiba WA (1990) Baroreflex control of cutaneous active vasodilator system in man. Circ Res 66: 1420–1426
Kendrick E, Oberg B, Wennergren G (1972) Vasoconstrictor fibre discharge to skeletal muscle, kidney, intestine and skin at varying levels of arterial baroreceptor activity in the cat. Acta Physiol Scand 85: 464–476
Kendrick E, Oberg B, Wennergren G (1972) Extent of engagement of various cardiovascular effectors to alterations of carotid sinus pressure. Acta Physiol Scand 86: 410–418
Kendrick JE, Matson GL (1973) A comparison of the cardiovascular responses to stimulation of the aortic and carotid sinus nerves of the dog. Proc Soc Exp Biol Med 144: 404–411
Kendrick JE, Matson GL (1975) Central summation of barosensory impulses over both carotid sinus nerves in the dog. Proc Soc Exp Biol Med 149: 158–162
Kendrick JE, Matson GL, Lalley PM (1979) Central interaction between the baroreceptor reflexes from the carotid sinus and aortic arch. Am J Physiol 236 (Heart Circ Physiol 5): H127–H133
Kent BB, Drane JW, Manning JW (1971) Suprapontine contributions to the carotid sinus reflex in the cat. Circ Res 29: 534–541
Kezdi P, Geller E (1968) Baroreceptor control of postganglionic sympathetic nerve discharge. Am J Physiol 214 (3): 427–435
Kirchheim H (1969) Effect of common carotid occlusion on arterial blood pressure and on kidney blood flow in unanesthetized dogs. Arch Gesamte Physiol 306: 119–134
Kirchheim H (1976) Systemic arterial baroreceptor reflexes. Physiol Rev 56: 100–176
Kirchheim H, Gross R (1971) Hemodynamics of the carotid sinus reflex elicited by bilateral carotid occlusion in the conscious dog. Effect of (alpha) and beta-adrenergic blockage on the reflex response. Arch Gesamte Physiol 327: 203–224
Kjellmer I (1965) On the competition between metabolic vasodilation and neurogenic vasoconstriction in skeletal muscle. Acta Physiol Scand 63: 450–459
Koch E (1931) Die reflektorische Selbststeuerung des Kreislaufes. In: Kisch B (ed) Ergebnisse der Kreislaufforschung, vol 1. Steinkopf Dresden pp 1–234
Koepchen HP, Langhorst P, Seller H, Polster J, Wagner PH (1967) Neuronale Aktivität im unteren Hirnstamm mit Beziehung zum Kreislauf. Arch Ges Physiol 294: 40–64
Kollai M, Koizumi M (1989) Cardiac vagal and sympathetic nerve responses to baroreceptor stimulation in the dog. Arch Ges Physiol 413: 365–371
Korner PI (1971) Intergrative neural cardiovascular control. Physiol Rev 51: 312–367
Korner PI (1979) Central nervous control of autonomic cardiovascular function. In: Berne RM (ed) The cardiovascular system. The heart. American Physiological Society, Bethesda, pp 691–739 (Handbook of physiology, sect 2, vol I )
Korner PI (1989) Baroreceptor resetting and other determinants of baroreflex properties in hypertension. Clin Exp Pharmacol Physiol [Suppl] 15: 45–64
Koster G, Tschermak A (1903) Über den N. depressor als Reflexnerv der Aorta. Arch Gesamte Physiol 93: 24–38
Koushanpour E, McGee J (1969) Effect of mean pressure on carotid sinus baroreceptor response to pulsatile pressure. Am J Physiol 216: 599–603
Krogh A (1912) The regulation of the supply of blood to the right heart. Scand Arch Physiol 27: 227–248
Kumada M, Schramm LP, Altmansberger RA, Sagawa K (1975) Modulation of carotid sinus baroreceptor reflex by hypothalamic defense response. Am J Physiol 228: 34–45
Kunze DL (1972) Reflex discharge patterns of cardiac vagal efferent fibres. J Physiol (Lond) 222: 1–16
Lambert CR Jr, Nichols WW, Pepine CJ (1983) Indices of ventricular contractile state: comparative sensitivity and specificity. Am Heart J 106: 136–144
Landgren S (1952) Baroreceptor activity in the carotid sinus nerve and the distensibility of the sinus wall. Acta Physiol Scand 26: 35–56
Levison WH, Barnett GO, Jackson WD (1966) Nonlinear analysis of the baroreceptor reflex system. Circ Res 18: 673–682
Levy MN, Martin PJ (1979) Neural control of the heart. In: Berne RM (ed) The cardiovascular system. The heart, American Physiological Society, Bethesda, pp 581–620 (Handbook of physiology, sect 2, vol I )
Levy MN, Zieske H (1969) Autonomic control of cardiac pacemaker activity and atrioventricular transmission. J Appl Physiol 27: 465–470
Levy MN, Ng M, Lipman RI, Zieske H (1966) Vagus nerves and baroreceptor control of ventricular performance. Circ Res 18: 101–106
Levy MN, Ng ML, Zieske H (1966) Functional distribution of the peripheral cardiac sympathetic pathways. Circ Res 19: 650–661
Levy MN, Ng ML, Zieske H (1966) Cardiac and respiratory effects of aortic arch baroreceptor stimulation. Circ Res 19: 930–939
Limet R, Fourny J, Kennedy JH (1975) Effects of the carotid sinus reflex upon coronary vessel tone. J Surg Res 19: 199–207
Little WC (1985) The left ventricular dP/dimax-end-diastolic volume relation in closed-chest dogs. Circ Res 56: 808–815
Loeb JM, deTarnowsky JM (1988) Modulation of atrioventricular conduction in vivo: integration of heart rate and autonomic neural input. Prog Clin Biol Res 275: 169–186
Ludbrook J (1983) Reflex control of blood pressure during exercise. Annu Rev Physiol 45: 155–168
Ludbrook J (1984) Concern about gain: is this the best measure of performance of cardiovascular reflexes? Clin Exp Pharmacol Physiol 11: 385–389
Mancia G, Mark AL (1983) Arterial baroreflexes in humans. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 755–793 (Handbook of physiology, sect 2, vol III, part 2 )
Mark AL, Mancia G (1983) Cardiopulmonary baroreflexes in humans. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 795–813 (Handbook of physiology, sect 2, vol III, part 2 )
Martin PJ, Levy MN, Zieske H (1969) Bilateral carotid sinus control of ventricular performance in the dog. Circ Res 24: 321–337
Melcher A, Donald DE (1981) Maintained ability of carotid baroreflex to regulate arterial pressure during exercise. Am J Physiol 241 (Heart Circ Physiol 10): H838–H849
Meredith J, Mendez C, Mueller WI, Moe GK (1968) Electrical excitability of atrioventricvular nodal cells Circ Res 23: 69–85
Mohrman DE, Feigl EO (1978) Competition between sympathetic vasoconstriction and metabolic vasodilation in the canine coronary circulation. Circ Res 142: 79–86
Moissejeff E (1926) Zur Kenntnis des Carotissinus reflexes. Z Gesamte Exp Med 53: 693–704
Morita H, Vatner SF (1985) Effects of hemorrhage on renal nerve activity in conscious dogs. Circ Res 57: 788–793
Mosley JG (1969) A reduction in some vasodilator responses in free-standing man. Cardiovasc Res 3: 14–21
Ninomiya I, Nisimaru N, Irisawa H (1967) Aortic nervous activities in response to pulsatile and nonpulsatile pressure. Am J Physiol 213: 1504–1511
Ninomiya I, Irisawa H (1969) Summation of baroreceptor reflex effects on sympathetic nerve activities. Am J Physiol 216 (6): 1330–1336
Ninomiya I, Nisimaru N, Irisawa H (1971) Sympathetic nerve activity to the spleen, kidney and heart in response to baroreceptor input. Am J Physiol 221: 1346–1351
O’Leary DS, Johnson JM (1989) Baroreflex control of the rat tail circulation in normothermia and hyperthermia. J Appl Physiol 66: 1234–1241
O’Leary DS, Johnson JM, Taylor WF (1985) Mode of neural control mediating rat tail vasodilation during heating. J Appl Physiol 59: 1533–1538
O’Leary DS, Rowell LB, Scher AM (1991) Baroreflex induced vasoconstriction in active skeletal muscle of conscious dogs. Am J Physiol (in press)
O’Leary DS, Scher AM (1990) Time course of recovery of arterial pressure control after carotid denervation. Am J Physiol 258 (Heart Circ Physiol 27): H73–H79
O’Leary DS, Scher AM, Bassett JE (1989) Effects of steps in cardiac output and arterial pressure in awake dogs with AV block. Am J Physiol 256 (Heart Circ Physiol 25): H361–367
Oberg B, Thoren P (1972) Increased activity in left ventricular receptors during hemorrhage or occlusion of caval veins in the cat — a possible cause of the vasovagal reaction. Acta Physiol Scand 81: 164–173
Pang CCY (1983) Effect of vasopressin antagonist and saralasin on regional blood flow following hemorrhage. Am J Physiol 245: H749–H755
Pelletier CL, Clement DL, Shepherd JT (1972) Comparison of afferent activity of canine aortic and sinus nerves. Circ Res 31: 557–568
Pickering TG, Gribbin B, Strange Petersen E, Cunningham DJC, Sleight P (1972) Effects of autonomic blockade on the baroreflex in man at rest and during exercise. Circ Res 30: 177–185
Powell JR, Feigl EO (1979) Carotid sinus reflex coronary vasoconstriction during controlled myocardial oxygen metabloism in the dog. Circ Res 44: 44–51
Raymundo H, Scher A, O’Leary DS, Sampson P (1989) Cardiovascular control by arterial and cardiopulmonary baroreceptors in awake dogs with atrioventricular block. Am J Physiol 257 (Heart Circ Physiol 26): H2048–H2058
Rea RF, Eckberg DL (1987) Carotid baroreceptor-muscle sympathetic relation in humans. Am J Physiol (Regulatory Integrative Comp Physiol 22 ): R929–R934
Reis DJ, Doba N, Synder DW, Nathan MA (1977) Brain lesions and hypertension; chronic lability and elevation of arterial pressure produced by electrolytic lesions and 6-hydroxydopamine treatment of nucleus tractus solitari ( NTS) in rat and cat. Prog Brain Res 47: 169–188
Remensnyder JP, Mitchell JH, Sarnoff SJ (1962) Functional sympatholysis during muscular activity. Circ Res 11: 370–380
Richter D, Keck W, Seller H (1970) The course of inhibition of sympathetic activity during various patterns of carotid sinus nerve stimulation. Arch Gesamte Physiol 317: 110–123
Riggs DS (1970) Control theory and physiological feedback mechanisms. Williams and Wilkins, Baltimore
Rosenbleuth A (1932) The chemical mediation of autonomic nervous impulses as evidenced by summation of responses. Am J Physiol 102: 12–38
Ross J Jr, Sonnenblick EH, Kaiser GA, Frommer PI, Braunwald E (1970) Electroaugmentation of ventricular performance and oxygen consumption by repetitive application of paired electrical stimuli. Circ Res 16: 332–342
Rothe CF (1983) Reflex control of veins and vascular capacitance. Physiol Rev 63: 1281–1342
Rothe C (1983) Venous system: physiology of the capacitance vessels. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 397–452 (Handbook of physiology, sect 2, vol III, part 1 )
Rowell LB (1986) Human circulation regulation during physical stress. Oxford University Press, New York
Rowell LB, Johnson JM (1984) Role of the splanchnic circulation in reflex control of the cardiovascular system. In: Shepherd AP, Granger DN (eds) Physiology of the intestinal circulation Raven, New York, pp 153–164
Rowell LB, O’Leary D (1990) Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes. J Appl Physiol 69: 407–418
Rowell LB, Wyss CR, Brengelmann GL (1973) Sustaned human skin and muscle vasoconstriction with reduced baroreceptor activity. J Appl Physiol 34: 639–643
Rutlen DL, Supple EN, Powell WJ Jr (1981) Beta-adrenergic regulation of total systemic intravascular volume in the dog. Circ Res. 48: 112–120
Sagawa K (1978) Concerning “gain”. Am J Physiol 235: H117
Sagawa K, Watanabe K (1965) Summation of bilateral carotid sinus signals in the barostatic reflex. Am J Physiol 209: 1278–1286
Sagawa K (1983) Baroreflex control of systemic arterial pressure and vascular bed. In: Berne RM (ed) The cardiovascular system. Peripheral circulation and organ blood flow. American Physiological Society, Bethesda, pp 453–496 (Handbook of physiology, sect 2, vol III, part 2 )
Sarnoff SJ, Gilmore JP, Brockman SK, Mitchell JH, Linden RJ (1960) Regulation of ventricular contraction by the carotid sinus: its effect on atrial and ventricular dynamics. Circ Res 8: 1123–1136
Scher AM, Young AC (1963) Servoanalysis of carotid sinus reflex effects on peripheral resistance. Circ Res 12: 152–162
Scher AM, Young AC (1970) Reflex control of heart rate in the unanesthetized dog. Am J Physiol 218: 780–789
Schmidt RM, Kumada M, Sagawa K (1971) Cardiac output and total peripheral resistance in carotid sinus reflex. Am J Physiol 221: 480–487
Seller H, Iiiert M (1969) The localization of the first synapse in the carotid sinus baroreceptor reflex pathway and its alteration of the afferent input. Arch Gesamte Physiol 306: 1–19
Shepherd AP, Riedel GL, Keeton TK (1988) Perfused rat intestine for study of norepinephrine release. Am J Physiol 254 (Heart Circ Physiol 23): H1187–H1193
Shipley RE, Gregg DE (1945) The cardiac response to stimulation of the stellate ganglia and cardiac nerves. Am J Physiol 143: 396–401
Smyth HS, Sleight P, Pickering GW (1969) Reflex regulation of arterial pressure during sleep in man: a quantitative method of assessing baroreflex sensitivity. Circ Res 24: 109–121
Sparks HV, Bohr DF (1962) Effect of stretch on passive tension and contractility of isolated vascular smooth muscle. Am J Physiol 202: 835–840
Spickler JW, Kezdi P (1967) Dynamic response characteristics of the carotid sinus baroreceptors. Am J Physiol 212: 472–476
Spickler JW, Kezdi P (1969) Probability of spike summations in baroreceptor electroneurograms. J Appl Physiol 27: 919–922
Spyer KM (1981) Neural organisation and control of the baroreceptor reflex. Rev Physiol Biochem Pharmacol 88: 23–124
Stegemann J, Gothe M, Geisen K (1966) Zur regeltheoretischen Analyse des Blutkreislaufes. III. Das Verhalten des arteriellen Mitteldruckes bei sinusförmigen Druckanderungen verschiedener Frequenz im isolierten Carotissinus des Hundes. Pflugers Arch Gesamte Physiol Menschen Tiere 287: 265–275
Stegemann J, Tibes U (1969) Sinusoidal stimulation of carotid sinus baroreceptors and peripheral blood pressure in dogs. Ann NY Acad Sci 156: 787–795
Stephenson RB, Donald DE (1980) Reversible vascular isolation of carotid sinuses in conscious dogs. Am J Physiol 238 (Heart Circ Physiol 7): H809–H814
Stephenson RB, Donald DE (1980) Reflexes from isolated carotid sinuses of intact and vagotomized conscious dogs. Am J Physiol 238 (Heart Circ Physiol 7): H815–822
Spyer KM (1981) Neural organization and control of the baroreceptor reflex. Rev Physiol Biochem Pharmacol 88: 23–124
Stinnet HO, Peterson DF, Bishop VS (1976) Rabbit cardiovascular responses to aortic nerve stimulation at fixed carotid pressure. Am J Physiol 236 (Heart 5): H769–H774
Stinnett HO, Peterson DF, Bishop VS (1979) Rabbit cardiovascular responses to aortic nerve stimulation at fixed carotid sinus pressure. Am J Physiol 236 (Heart Circ Physiol 5): H769–H774
Strack AM, Sawyer WB, Hughes JH, Piatt KB, Loewy AD (1989) A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections. Brain Res 491 (1): 156–172
Suga H, Sagawa K, Kostiuk DP (1976) Controls of ventricular contractility assessed by pressure-volume ratio, EmSLX. Cardiovasc Res 10: 582–592
Sunagawa K, Maughan WL, Burkoff D, Sagawa K (1983) Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol 245 (Heart Circ Physiol 14): H773–H780
Sundloff G, Wallin BG (1978) Human muscle nerve sympathetic activity at rest. Relationship to blood pressure and age. J Physiol (Lond) 274: 621–637
Taylor WF, Johnson JM, O’Leary DS, Park MK (1984) Modification of the cutaneous vascular response to exercise by local skin temperature. J Appl Physiol 57: 1878–1884
Thaemert JC (1970) Atrioventricular node innervation in ultrastructural three dimensions. Am J Anat 128: 239–264
Tucker DC, Saper CB (1985) Specificity of spinal projections from hypothalamic and brainstem areas which innervate sympathetic preganglionic neurons. Brain Res 360: 159–164
Van de Bos GC, Elzinga G, Westerhof N, Noble MI (1973) Problems in the use of indices of myocardial contractility. Cardiovasc Res 7: 834–848
Vanhoutte PM (1980) Physical factors of regulation. In: Bohr DF, Somlyo AP, Sparks HV (eds) The cardiovascular system. Vascular smooth muscle. American Physiological Society, Bethesda, pp 443–474 (Handbook of physiology, sect 2, vol I I )
Vatner SF (1974) Effects of hemorrhage on regional blood flow distribution in dogs and primates. J Clin Invest 54: 225–235
Vatner SF, Franklin D, Van Citters RL, Braunwald E (1970) Effects of carotid sinus nerve stimulation on blood-flow distribution in conscious dogs at rest and during exercise. Circ Res 27: 495–503
Vatner SF, Higgins CB, Franklin D, and Braunwald E (1974) Extent of carotid sinus regulation of the myocardial contractile state in conscious dogs. J Clin Invest 51: 995–1008
Wallin BG (1988) Peripheral sympathetic neural activity in conscious humans. Annu Rev Physiol 50: 565–576
Wang SC, Borison HI (1947) An analysis of the carotid sinus cardiovascular reflex mechanism. Am J Physiol 150: 712–721
Warner HR, Cox A (1962) A mathematical model of heart rate control by sympathetic and vagus efferent information. J Appl Physiol 17: 349–355
Weinstock M, Korner PI, Head GA, Dorwad PK (1988) Differentiation of cardiac baroreflex properties by cuff and drug methods in two rabbit strains. Am J Physiol 255: 654–664
White SW, Porges WL, Reid JVO, Bhagat CI (1976) Baroreflex control of coronary conductance in normotensive and renal hypertensive conscious dogs with complete heart block. Clin Sci Mol Med 51: 361–364
Wyss CR, Rowell LB (1976) Lack of humanlike active vasodilation in skin of heat-stressed baboons. J Appl Physiol 41: 528–531
Yamazaki T, Sagawa K (1989) Summation of sinoaortic baroreflexes depends on size of input signals. Am J Physiol 257 (Heart Circ Physiol 26): H465–H472
Yoran C, Higginson L, Romero MA, Covell JW, Ross J Jr (1981) Reflex sympathetic augmentation of left-ventricular inotropic state in the conscious dog. Am J Physiol 241 (Heart Circ Physiol 10): H857–H863
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© 1991 Springer-Verlag Berlin Heidelberg
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Scher, A.M., O’Leary, D.S., Sheriff, D.D. (1991). Arterial Baroreceptor Regulation of Peripheral Resistance and of Cardiac Performance. In: Persson, P.B., Kirchheim, H.R. (eds) Baroreceptor Reflexes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76366-3_4
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