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Abstract

The search for a specific, clinically useful treatment to arrest or reverse the autodigestive process believed to be the central pathophysiologic event in acute pancreatitis has so far been frustrating and unsuccessful. One major approach to this problem has been the use of agents such as anticholinergic drugs, glucagon, calcitonin, and somatostatin which have been shown in physiological studies to inhibit pancreatic exocrine secretion. Unfortunately, none of these substances proved to be of value in prospective, randomized clinical trials [1].

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© 1991 Springer-Verlag Berlin Heidelberg

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Grendell, J.H. (1991). Experimental Pancreatitis. In: Adler, G., Beglinger, C. (eds) Cholecystokinin Antagonists in Gastroenterology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76362-5_21

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  • DOI: https://doi.org/10.1007/978-3-642-76362-5_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76364-9

  • Online ISBN: 978-3-642-76362-5

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