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Risk factors which determine the long term outcome of Neodymium-YAG laser palliation of colorectal carcinoma

  • E. Van Cutsem
  • A. Boonen
  • K. Geboes
  • G. Coremans
  • M. Hiele
  • G. Vantrappen
  • P. Rutgeerts
Conference paper

Abstract

We have analysed the long term results of YAG laser palliation for incurable colorectal carcinoma in 88 patients. Although initial palliation was achieved in 82%, good palliation could only be maintained in 51% and 41% of patients surviving 6 months and 12 months respectively. The relative inefficacy of YAG laser therapy for palliation of rectal cancer is due to the failure to control extraluminal tumour growth, complications of YAG laser therapy and the poor general condition of these elderly patients. Factors influencing the efficacy of palliation, besides life expectancy, included T classification, and length of the neoplastic stricture. Treatment-related mortality due to perforation was 2.3%. YAG laser therapy, applied as the sole therapeutic modality, is effective for short term palliation of incurable colorectal carcinoma, but is not adequate for long term palliation in most patients. Trials should be conducted to study the effect of combined treatment (e.g. laser + radiotherapy) on palliation.

Keywords

Laser Therapy Rectovaginal Fistula Life Table Analysis Good Palliation Laser Session 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Brunetaud JM, Manoury V, Ducrotte P, Cochelard D, Cortot A, Paris JC (1987) Palliative treatment of rectosigmoid carcinoma by laser endoscopie photoablation. Gastroenterology 92: 663–668PubMedGoogle Scholar
  2. 2.
    Escourrou J, Delvaux M, Frexinos J, Ribet A (1986) Traitement du cancer du rectum par le laser neodyme YAG. Gastroenterol Clin Biol 10: 152–157PubMedGoogle Scholar
  3. 3.
    Mathus-Vliegen EM, Tytgat GN (1986) Neodymium-YAG laser photocoagulation in gastroenterology: its role in palliation of colorectal cancer. Lasers Med Sci 1: 75–80CrossRefGoogle Scholar
  4. 4.
    Bown SG, Barr H, Matthewson K (1986) Endoscopie treatment of inoperable colorectal cancers with the NeodymiumYAG laser. Br J Surg 73: 949–952PubMedCrossRefGoogle Scholar
  5. 5.
    Kiefhaber P. Kiefhaber K, Huber F (1986) Preoperative Neodymium-YAG laser treatment of obstructive colon cancer. Endoscopy 18 [Suppl 1]: 44–46Google Scholar
  6. 6.
    Lambert R, Sabben G, Guyot P, Chavaillon A, Descos F (1984) Cancer of the rectum: results of laser treatment. Laser Med Surg 3: 342Google Scholar
  7. 7.
    Morris AI, Krasner N (1985) Laser irradiation of inoperable tumours of the colon and rectum. Br Med J 290: 1948CrossRefGoogle Scholar
  8. 8.
    Naveau S, Roulot D, Zourabichvili O, Poitrine A, Poynard T, Chaput JC (1986) Traitement palliatif des adénocarcinomes du rectum par le laser YAG Néodyme: Résultats immédiats et à long terme. Gastroenterol Clin Biol 10: 651–655PubMedGoogle Scholar
  9. 9.
    Rutgeerts P, Vantrappen G, D’Heygere F, Geboes K (1987) Endoscopie contact Nd-YAG laser therapy for colorectal cancer: a randomized comparison with non-contact therapy. Lasers Med Sci 2: 69–72CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • E. Van Cutsem
    • 1
  • A. Boonen
    • 1
  • K. Geboes
    • 1
  • G. Coremans
    • 1
  • M. Hiele
    • 1
  • G. Vantrappen
    • 1
  • P. Rutgeerts
    • 1
    • 2
  1. 1.Department of Medicine, Division of Gastroenterology and Department of PathologyUniversity HospitalLeuvenBelgium
  2. 2.U.Z. GasthuisbergLeuvenBelgium

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