The Molecular Biology of Prostate Cancer

  • Jan Trapman
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)


Induction and progressive growth of cancer are considered to be genetic processes. A series of mutations in different genes is believed to be necessary for development of a malignant tumour. Genetic changes can vary from a drastic damage of the genomic structure (gene amplification, chromosomal translocation, gene deletion) to a very subtle point mutation. A mutation in the gene can influence the properties of the protein product and/or its expression level.


Androgen Receptor Prostate Tumour Translocation Breakpoint Human Androgen Receptor Cellular Oncogene 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Jan Trapman
    • 1
  1. 1.Department of PathologyErasmus UniversityRotterdamThe Netherlands

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