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The Molecular Biology of Prostate Cancer

  • Jan Trapman
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)

Abstract

Induction and progressive growth of cancer are considered to be genetic processes. A series of mutations in different genes is believed to be necessary for development of a malignant tumour. Genetic changes can vary from a drastic damage of the genomic structure (gene amplification, chromosomal translocation, gene deletion) to a very subtle point mutation. A mutation in the gene can influence the properties of the protein product and/or its expression level.

Keywords

Androgen Receptor Prostate Tumour Translocation Breakpoint Human Androgen Receptor Cellular Oncogene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Jan Trapman
    • 1
  1. 1.Department of PathologyErasmus UniversityRotterdamThe Netherlands

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