Thalamic Dementia and Pseudodementia

  • J. Bogousslavsky
Conference paper

Abstract

Bilateral lesions of the thalamus may yield severe neuropsychological disturbances, including memory, speech, and visuospatial dysfunction; furthermore, in some instances, a condition known as thalamic dementia may develop [3,6,8,11,19], in which amnesia, speech disturbances, and confusion may be associated with apathy, flattened affect, and aspontaneity of motor acts.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Baron JC, D’Antona R, Serdaru M, Pantano P, Bousser MG, Samson Y (1986) Hypométabolisme cortical après lésion thalamique chez l’homme: étude par la tomographic à positons. Rev Neurol 142:465–474PubMedGoogle Scholar
  2. 2.
    Bogousslavsky J, Miklossy J, Deruaz JP, Regli F, Assal G (1986) Unilateral left paramedian infarction of thalamus and midbrain: a clinico-pathological study. J Neurol Neurosurg Psychiat 49:686–694PubMedCrossRefGoogle Scholar
  3. 3.
    Bogousslavsky J, Regli F, Uske A (1988) Thalamic infarcts: clinical syndromes, etiology, and prognosis. Neurology 38:837–848PubMedGoogle Scholar
  4. 4.
    Bogousslavsky J, Ferrazzini M, Regli F, Assal G, Tanabe H, Delaloye-Bischof A (1988) Manic delirium and frontal-like syndrome with paramedian infarction of the right thalamus. J Neurol Neurosurg Psychiat 51:116–119PubMedCrossRefGoogle Scholar
  5. 5.
    Bogousslavsky J, Van Melle G, Regli F, for the Lausanne Stroke Registry (1988) The Lausanne Stroke Registry: analysis of 1000 consecutive patients with first stroke. Stroke 19:1083–1092PubMedCrossRefGoogle Scholar
  6. 6.
    Castaigne P, Buge A, Cambier J, Escourolle R, Brunet P, Degos JD (1966) Démence thalamique d’origine vasculaire par ramollissement bilatéral, limité au territoire du pédicule rétromamillaire. A propos de deux observations anatomo-cliniques. Rev Neurol 114:89–107PubMedGoogle Scholar
  7. 7.
    Gentilini M, De Renzi E, Crisi G (1987) Bilateral paramedian thalamic artery infarcts: Report of 8 cases. J Neurol Neurosurg Psychiat 50:900–909PubMedCrossRefGoogle Scholar
  8. 8.
    Grünthal E (1942) Über thalamische Demenz. Monatsschr Psychiatr Neurol 106:114–128CrossRefGoogle Scholar
  9. 9.
    Haber SN, Groenewegen HJ, Grove EA, Nauta WJH (1985) Efferent connections of the ventral pallidum in the rat. Evidence of a dual striato-pallidofugal pathway. J Comp Neurol 238:322–335CrossRefGoogle Scholar
  10. 10.
    Habib M, Poncet M (1988) Perte de l’élan vital, de l’intérêt et de l’affectivité (syndrome athymhormique) au cours de lésions lacunaires des corps striés. Rev Neurol 144:571–577PubMedGoogle Scholar
  11. 11.
    Katz DI, Alexander MP, Mandell AM (1987) Dementia following strokes in the mesencephalon and diencephalon. Arch Neurol 44:1127–1133PubMedCrossRefGoogle Scholar
  12. 12.
    Laplane D, Baulac M (1982) Perte de l’autoactivation psychique. Activité compulsive d’allure obsessionnelle. Lésion lenticulaire bilatérale. Rev Neurol 138:137–141PubMedGoogle Scholar
  13. 13.
    Laplane D, Widlocher D, Pillon B, Baulac M, Binoux F (1981) Comportement compulsif d’allure obsessionnelle par nécrose circonscrite bilatérale pallido-striatale. Encéphalopathie par piqûre de guêpe. Rev Neurol 137:269–276PubMedGoogle Scholar
  14. 14.
    Laplane D, Escourolle R, Degos JD, Sauron B, Massion H (1982) La négligence motrice d’origine thalamique. A propos de deux cas. Rev Neurol 138:201–211PubMedGoogle Scholar
  15. 15.
    Laplane D, Baulac M, Widlöcher D, Dubois B (1984) Pure psychic akinesia with bilateral lesions of basal ganglia. J Neurol Neurosurg Psychiat 47:377–385PubMedCrossRefGoogle Scholar
  16. 16.
    Laplane D, Dubois B, Pillon B, Baulac M (1988) Perte d’autoactivation psychique et activité mentale stéréotypée par lésion frontale. Rapports avec le trouble obsessivo-compulsif. Rev Neurol 144:564–570PubMedGoogle Scholar
  17. 17.
    Markowitsch HJ (1982) Thalamic mediodorsal nucleus and memory: a critical evaluation of studies in animal and man. Neurosci Biobehav Rev 6:351–380PubMedCrossRefGoogle Scholar
  18. 18.
    Miklossy J, Van der Loos H, Deruaz JP, Bogousslavsky J, Regli F (1987) Thalamic aphasia and neglect: cortical involvement as shown by anterograde axonal degeneration in the human brain. Proceedings, Cellular thalamic mechanisms, Verona (abstract)Google Scholar
  19. 19.
    Stern K Severe dementia associated with bilateral symmetrical degeneration of the thalamus. Brain 62:157–171Google Scholar
  20. 20.
    Stuss DT, Benson DF (1986) The frontal lobes. Raven, New YorkGoogle Scholar
  21. 21.
    Von Cramon DY, Hebel N, Schuri U (1985) A contribution to the anatomical basis of thalamic amnesia. Brain 108:993–1008CrossRefGoogle Scholar
  22. 22.
    Watson RT, Valentin E, Heilman KM (1981) Thalamic neglect. Possible role of the medial thalamus and nucleus reticularis in behavior. Arch Neurol 38:501–506PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • J. Bogousslavsky
    • 1
  1. 1.Centre Hospitalier Universitaire VaudoisLausanneSwitzerland

Personalised recommendations