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Cerebral Ischemia and Dementia pp 266–275Cite as

Magnetic Resonance Imaging and Spectroscopy: A Unique Approach to Ischemic Cerebrovascular Disease

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Abstract

During the past decades management of ischemic cerebrovascular disease was primarily directed to the prevention of stroke, rather than to the treatment of acute infarction. Today it is generally accepted that structural damage does not occur immediately and neurons may recover if therapy begins soon after onset of ischemia. Experimentally, infarction size may be reduced with restored (i.e., fibrinolysis) or improved (pharmacologic) cerebral blood flow, by increase of cellular tolerance to ischemia (i.e., hypothermia), or by prevention of secondary damage (i.e., Ca2+ antagonists) [22].

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References

  1. Aichner F, Gerstenbrand F (1989) Computed tomography in cerebrovascular disease. In: Vinken P, Bruin G, Klawans H (eds) Handbook of clinical neurology, vol 54 (10) Elsevier, Amsterdam, pp 47–80

    Google Scholar 

  2. Alfidi RJ, Masaryk TJ, Haake EM et al. (1987) MR-angiography of the peripheral, carotid, and coronary arteries. AJR 149:1097–1109

    PubMed  CAS  Google Scholar 

  3. Anderson C, Saloner D, Tsuruda J et al. (1990) Artifacts in maximum-intensity-projection display of MR angiograms. AJR 154:623–629

    PubMed  CAS  Google Scholar 

  4. Berkelbach van der Sprenkel J, Luyton P, van Rijen P et al. (1988) Cerebral lactate detected by regional proton magnetic resonance spectroscopy in a patient with cerebral infarction. Stroke 19:1556–1560

    Article  PubMed  CAS  Google Scholar 

  5. Bradley W, Waluch V, Lai K et al. (1984) The appearance of rapidly flowing blood on magnetic resonance imaging. AJR 143:1167–1174

    PubMed  Google Scholar 

  6. Brand-Zawadski M, Weinstein P, Bartkowski H et al. (1987) MR imaging and spectroscopy in clinical and experimental cerebral ischemia: a review. AJR 148:579–588

    Google Scholar 

  7. Brott T, Marler J, Olinger C et al. (1989) Measurement of acute cerebral infarction lesion size by computed tomography. Stroke 20:871–875

    Article  PubMed  CAS  Google Scholar 

  8. Bruhn H, Frahm J, Gyngell M et al. (1989) Cerebral metabolism in man after acute stroke: new observations using localized proton NMR spectroscopy. Mag Res Med 9:126–131

    Article  CAS  Google Scholar 

  9. Edelman R, Johnson K, Buxton R et al. (1986) MR of hemorrhage: a new approach. AJNR 7:751–756

    PubMed  CAS  Google Scholar 

  10. Felber S, Aichner F (1989) MR-Angiographie der intrakraniellen Gefäße. Vasa 27: 373–375

    CAS  Google Scholar 

  11. Felber S, Ruggieri P, Laub G et al. (1988) MR-Angiography: application to carotid atherosclerotic disease. Magn Res Imag 6(1):46

    Google Scholar 

  12. Felber S, Laub G, König H et al. (1988) 3D-Imaging of neurologic disorders using gradient echo sequences with short TE. 2nd European congress of NMR in medicine and biology, Berlin, Book of Abstracts, p 72

    Google Scholar 

  13. Felber S, Sauter R, Aichner F (1989) Localized proton spectroscopy applied to cerebral neoplasms and ischemia at a clinical 1.5T MR-system. 8th Annual meeting of the Society of Magnetic Resonance in Medicine, Aug 12–18, Amsterdam. Book of Abstracts, vol 1 p 450

    Google Scholar 

  14. Felber S, Ruggieri P, Laub G et al. (1989) 3D-MR angiography of atherosclerotic cerebrovascular disease. In: Meyer J (ed) Cerebral vascular disease 7. Elsevier, Amsterdam, pp 123–126

    Google Scholar 

  15. Felber S, Zimmer V, Aichner F et al. (1990) 3D-MR-Angiography of the intracranial vessels: clinical application and comparison to transcranial ultrasound. In: Schneider G et al. (eds) Digitale Bildgebung, interventionelle Radiologie, integrierte Digitale Radiologie. Blackwell Ueberreuther Wissenschaft, Berlin pp 269–272

    Google Scholar 

  16. Felber S, Birbamer G, Benesch H et al. (1990) Isotropic 3D-MR imaging applied to degenerative disorders of the brain. In: Schneider G et al. (eds) Digitale Bildgebung, interventionelle Radiologie, integrierte digitale Radiologie. Blackwell Ueberreuther Wissenschaft, Berlin, pp 282–285

    Google Scholar 

  17. Felber S, Aichner F, Birbamer G et al. (1990) 3D-postprocessing in der Magnetresonanztomographie. Biomed Technik 35(2):240–241

    Article  Google Scholar 

  18. Felber S, Aichner F, Sauter R (1990) Sequential 1H MR-spectroscopy: new insights into ischemic metabolism. J Neurol 237:156–157

    Google Scholar 

  19. Fieschi C, Argentino C, Lenzi G et al. (1988) Therapeutic window for pharmacological treatment in acute focal cerebral ischemia. Ann NY Acad Sci 522:662–666

    Article  PubMed  CAS  Google Scholar 

  20. Frahm J, Merbold D, Hänicke W (1987) Localized proton spectroscopy using stimulated echoes. J Magn Res 72:502–508

    Article  CAS  Google Scholar 

  21. Gomori JM, Grossmann RI, Yu-Ip C et al. (1987) NMR relaxation times of blood: dependance on field strength, oxidation state and cell integrity. J Comp Assist Tomogr 11:684–690

    Article  CAS  Google Scholar 

  22. Heiss WD (1989) Medical management of cerebral infarction. In: Vinken P, Bruin G, Klawans H (eds) Handbook of clinical neurology, vol 53 (a). Elsevier, Amsterdam, pp 417–439

    Google Scholar 

  23. Kinkel WR, Jacobs L (1976) Computerized axial transverse tomography in cerebrovascular disease. Neurology 26:924–930

    PubMed  CAS  Google Scholar 

  24. Kirkpatrick J, Hayman L (1987) White matter lesions in MR-imaging of clinically healthy brains of elderly subjects: possible pathologic basis. Radiology 162:509–511

    PubMed  CAS  Google Scholar 

  25. Laub GA, Kaiser WA (1988) MR angiography with gradient motion refocussing. J Comp Assist Tomogr 12:377–382

    Article  CAS  Google Scholar 

  26. Lechner H, Schmidt R, Götz B et al. (1988) Nuclear magnetic resonance is imaging of white matter lesions and risk factors for stroke in normal individuals. Stroke 19:263–265

    Article  PubMed  CAS  Google Scholar 

  27. Masaryk T, Modic M, Ruggieri P et al. (1989) Three dimensional (volume) gradient-echo imaging of the carotid bifurcation: preliminary clinical experience. Radiology 171: 801–806

    PubMed  CAS  Google Scholar 

  28. Masaryk T, Modic M, Ross J et al. (1989) Intracranial circulation: preliminary clinical results with 3D (volume) MR-angiography. Radiology 171:793–799

    PubMed  CAS  Google Scholar 

  29. Rothrock J, Lyden P, Hesselink J et al. (1987) Brain magnetic resonance imaging in the evaluation of lacunar stroke. Stroke 18:781–786

    Article  PubMed  CAS  Google Scholar 

  30. Ruggieri P, Laub G, Masaryk T et al. (1989) Intracranial circulation: pulse sequence considerations in 3D (volume) MR angiography. Radiology 171:785–791

    PubMed  CAS  Google Scholar 

  31. Scalpe I (1988) Complications in cerebral angiography with iohexol (Omnipaque) and meglumine metrizoate (Isopaque). Neuroradiology 30:69–72

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Magnetic Resonance Imaging and Spectroscopy, and University Clinic of Neurology, University of Innsbruck, Anichstr. 35, A-6020, Innsbruck, Austria

    S. R. Felber, F. T. Aichner & F. Gerstenbrand

Authors
  1. S. R. Felber
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  2. F. T. Aichner
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  3. F. Gerstenbrand
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Editor information

Editors and Affiliations

  1. Neurologische Universitätsklinik, Sigmund-Freud-Str. 25, W-5300, Bonn 1, Germany

    Alexander Hartmann

  2. Physiologisches Institut der Universität, Im Neuenheimer Feld 326, W-6900, Heidelberg, Germany

    Wolfgang Kuschinsky

  3. Abt. für Pathochemie und Allg. Neurochemie, Pathologisches Institut der Universität, Im Neuenheimer Feld 220-221, W-6900, Heidelberg, Germany

    Siegfried Hoyer

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© 1991 Springer-Verlag Berlin Heidelberg

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Felber, S.R., Aichner, F.T., Gerstenbrand, F. (1991). Magnetic Resonance Imaging and Spectroscopy: A Unique Approach to Ischemic Cerebrovascular Disease. In: Hartmann, A., Kuschinsky, W., Hoyer, S. (eds) Cerebral Ischemia and Dementia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76208-6_31

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  • DOI: https://doi.org/10.1007/978-3-642-76208-6_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76210-9

  • Online ISBN: 978-3-642-76208-6

  • eBook Packages: Springer Book Archive

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