Electrophysiological Markers of the Early Stages of Alzheimer’s Disease

  • L. de Toledo-Morrell
  • F. Morrell
  • T. J. Hoeppner
  • R. Fortney
  • D. Bennett
Conference paper


The goal of this paper is to describe a noninvasive electrophysiological test we have developed in our laboratory which may have promise as a sensitive marker during the very early stages of probable Alzheimer’s disease (AD). We will also present preliminary data which indicate that the electrophysiological pattern shown by probable AD patients is different from that observed in patients with comparable dementia due to vascular causes or in depressed patients.


Memory Load Target Letter P300 Amplitude P300 Latency Choice Accuracy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • L. de Toledo-Morrell
    • 1
  • F. Morrell
    • 1
  • T. J. Hoeppner
    • 1
  • R. Fortney
    • 1
  • D. Bennett
    • 1
  1. 1.Department of Neurological Sciences and the Rush Alzheimer’s Disease CenterRush Medical CollegeChicagoUSA

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