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Inhibition of Atherogenesis In Vivo and In Vitro

  • E. L. Betz
Conference paper

Abstract

Prevention of stenosing or occluding thickening in the walls of arteries supplying blood to the brain has become important to experimental research with an increasing number of patients surviving a transient ischemic attack (TIA) or a stroke caused by occlusion or stenosis in these arteries. In the following report some experimental efforts in this direction are presented.

Keywords

Smooth Muscle Cell Coculture System Dextran Sulfate Smooth Muscle Cell Proliferation Endothelial Lining 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Betz E, Hämmerle H (1984) Arterienwandproliferate und Zellkulturen als Indikatoren für Hemmstoffe der Atherogenese. Funkt Biol Med 3:46–55Google Scholar
  2. 2.
    Betz E, Schlote W (1979) Responses of vessel walls to chronically applied electrical stimuli. Basic Res Cardiol 74:10–20PubMedCrossRefGoogle Scholar
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    Fotev Z, Betz E (1990) The inhibition of SMC proliferation following balloon injury in the carotid artery by the calcium-calmodulin antagonist, fendiline Pflügers Arch 415:R116Google Scholar
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    Hanke H, Oberhoff M, Strohschneider T, Betz E, Karsch KR (1989) Late morphological changes and occurrence of restenosis following balloon angioplasty in athersclerotic rabbit carotid arteries. Arteriosclerosis 9:737aGoogle Scholar
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    Hanke H, Strohschneider T, Oberhoff M, Betz E, Karsch KR (1989) Re-Stenosierung nach Angioplastie von experimentell erzeugten atheromatösen Plaques: Quantifizierung der Prolfierationsrate von glatten Muskelzellen (SMCs) (Abstract p 438). Z Kardiol 78 [Suppl 1]:121Google Scholar
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    Kling D, Holzschuh T, Betz E (1987) Temporal sequence of morphological alterations in artery walls during experimental atherogenesis - occurrence of leukocytes. Res Exp Med 187:237–250CrossRefGoogle Scholar
  7. 7.
    Strohschneider T (1989) Die Bedeutung von wiederholten Reizen bei der Induktion von atheromatösen Plaques. In: Betz E (ed) Die Anwendung aktueller Methoden in der Arteriosklerose-Forschung, Selbstverlag der Deutschen Gesellschaft Arterioskle-roseoforschung e. V., Tübingen, pp 244–251Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • E. L. Betz
    • 1
  1. 1.Institute of Physiology (I)University of TübingenTübingenGermany

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