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Incidental Carcinoma of the Prostate pp 63–73Cite as

Histogenesis of Incidental Carcinoma of the Prostate

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Abstract

The histogenesis of the incidental carcinoma of the prostate is first mentioned by Moore [64], by Baron and Angrist [3], and by Andrews [2]. Many more detailled studies have appeared later on [6, 8, 11, 20, 24, 25, 29, 38–40, 42, 43, 47, 49, 52, 53, 55–57]. It is particularly difficult to describe current concepts in this field because of the welter of conflicting theses and hypotheses, many of which seem the product of an overactive imagination rather than of empirical evidence.

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References

  1. Altenaehr E, Kastendieck H (1980) Proliferative patterns in prostatic carcinoma. In: Spring-Mills E, Hafez ESE (eds) Male accessory sex glands. Elsevier, New York, pp 437–455

    Google Scholar 

  2. Andrews GS (1949) Latent carcinoma of the prostate. J Clin Pathol 2:197–208

    Article  Google Scholar 

  3. Baron E, Angrist A (1941) Incidence of occult adenocarcinoma of the prostate after fifty years of age. Arch Pathol 48:787–797

    Google Scholar 

  4. Battaglia S (1985) Prostate accessory sex gland: Introduction. Appl Pathol 3:197

    Google Scholar 

  5. Battaglia S (1987) Classification of prostate atrophy. The Second Tokyo Symposium on Prostate Cancer. Abstracts, p 49

    Google Scholar 

  6. Battaglia S (1988) Epithelial hyperplasia of the prostate gland. In: Karr JP, Coffey DS, Gardner W (eds) Prognostic cytometry and cytopathology of prostate cancer. Elsevier, New York, pp 122–137

    Google Scholar 

  7. Battaglia S (1988) Panel discussion and questions. In: Karr JP, Coffey DS, Gardner W (eds) Prognostic cytometry and cytopathology of prostate cancer. Elsevier, New York, pp 37–44

    Google Scholar 

  8. Battaglia S (1988) Undeveloped prepuberal units in human prostate. XVII International Congress of the International Academy of Pathology. Dublin, p 338

    Google Scholar 

  9. Battaglia S (1989) Classification of prostate atrophy. In: Karr JP, Yamanaha H (eds) The second Tokyo symposium on prostate cancer. Elsevier, New York, pp 148–160

    Google Scholar 

  10. Battaglia S (1990) Incidental carcinoma of the prostate: complete examination of PBH-tissue. In: Altwein J, Faul P, Schneider W (eds) Incidental carcinoma of the prostate. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  11. Battaglia S (to be published) Undeveloped prepuberal units in human prostate

    Google Scholar 

  12. Battaglia S (to be published) Microcarcinoma of the prostate

    Google Scholar 

  13. Battaglia S, Barbolini G, Botticelli AR (1978) Klassifizierung und Differentialdiagnose des Prostatacarcinoms. Verh Dtsch Krebsges 1:233–240

    Google Scholar 

  14. Battaglia S, Barbolini G, Botticelli AR (1979) Early (stage A) prostatic cancer. IV Methodological criteria for histopathological diagnosis. Virchows Arch [A] 382:245–259

    Article  CAS  Google Scholar 

  15. Battaglia S, Barbolini G, Botticelli AR (1982) Il carcinoma focale della prostata. Istocitopatologia 4:45–49

    Google Scholar 

  16. Battaglia S, Barbolini G, Botticelli AR, Berri G, Nigrisoli E (1982) Early (stage A) prostatic cancer. VI. A critical look at the follow-up. Virchows Arch [A] 395:279–288

    Article  CAS  Google Scholar 

  17. Battaglia S, Barbolini G, Botticelli AR, Giarelli L (1983) Early (stage A) prostatic cancer. V. Stereotopography. Appl Pathol 1:164–179

    PubMed  CAS  Google Scholar 

  18. Battaglia S, Nigrisoli E, Botticelli AR, Barbolini G (1985) Prostate cambial (stem)-zone and microcarcinoma: immunohistochemical and morphometrical study approach. Appl Pathol 3:255–261

    PubMed  CAS  Google Scholar 

  19. Bostwick DG (1988) Premalignant lesions of the prostate. Semin Diagn Pathol 5:240–253

    PubMed  CAS  Google Scholar 

  20. Bostwick DG (1989) Origin of prostatic carcinoma. Progress in reproductive and urinary tract. Pathology 1:73–90

    Google Scholar 

  21. Bostwick DG, Brawer MK (1987) Prostatic intra-epithelial neoplasia and early invasion in prostate cancer. Cancer 59:788–794

    Article  PubMed  CAS  Google Scholar 

  22. Brawn PN (1982) Adenosis of the prostate: a dysplastic lesion that can be confused with prostate adenocarcinoma. Cancer 49:826–833

    Article  PubMed  CAS  Google Scholar 

  23. Brawn PN (1983) The dedifferentiation of prostate carcinoma. Cancer 52:246–251

    Article  PubMed  CAS  Google Scholar 

  24. Clark TD, Askin FB, Bagnell CR (1987) Nuclear roundness factor: a quantitative approach to grading in prostatic carcinoma, reliability of needle biopsy tissue, and the effect of tumor stage on usefulness. Prostate 10:199–206

    Article  PubMed  CAS  Google Scholar 

  25. Dhom G (1974) Differentialdiagnostische Probleme des Prostatacarcinoms (Erfahrungen mit dem Prostatacarcinom-Register). Beitr Pathol 153:203–220

    PubMed  CAS  Google Scholar 

  26. Dhom G (1979) Frühe neoplastische Veränderungen der Prostata. Verh Dtsch Ges Pathol 63:218–231

    Google Scholar 

  27. Dhom G (1985) Histopathology of prostate carcinoma. Diagnosis and differential diagnosis. Pathol Res Pract 179:277–303

    Article  PubMed  CAS  Google Scholar 

  28. Diamond DA, Berry SJ, Umbricht C, Jewett HJ, Coffey DS (1982) Computerized image analysis of nuclear shape as a prognostic factor for prostatic cancer. Prostate 3:321–332

    Article  PubMed  CAS  Google Scholar 

  29. Epstein JI, Berry SJ, Eggleston JC (1984) Nuclear roundness factor. A predictor of progression in untreated stage A2 prostate cancer. Cancer 54:1666–1677

    Article  PubMed  CAS  Google Scholar 

  30. Franks LM (1954) Atrophy and hyperplasia in the prostate proper. J Pathol Bacteriol 68:617–622

    Article  PubMed  CAS  Google Scholar 

  31. Franks LM (1954) Latent carcinoma of the prostate. J Pathol Bacteriol 68:603–616

    Article  PubMed  CAS  Google Scholar 

  32. Gleason DF (1985) Atypical hyperplasia, benign hyperplasia, and well-differentiated adenocarcinoma of the prostate. Am J Surg Pathol 9 [Suppl 3]:53–67

    Google Scholar 

  33. Gleason DF (1966) Classification of prostatic carcinomas. Cancer Ther Rep 50:125–128

    CAS  Google Scholar 

  34. Gleason DF, Mellinger GT, Veterans Administr. Cooperative Urological Research Group (1974) Prediction of prognosis for prostatic adenocarcinoma and combined histological grading and clinical staging. J Urol 111:58–64

    PubMed  CAS  Google Scholar 

  35. Hedrick L, Epstein JI (1988) Use of keratin 903 as an adjunct in the diagnosis of prostatic carcinoma. Lab Invest 58:38A

    Google Scholar 

  36. Helpap B (1989) Pathology der ableitenden Harnwege und der Prostata. Springer, Berlin Heidelberg New York

    Google Scholar 

  37. Humphrey P, Vollmer RT (1988) The ratio of prostate chips with cancer: a new measure of tumor extent and its relationship to grade and prognosis. Hum Pathol 19:411–418

    Article  PubMed  CAS  Google Scholar 

  38. Jewett HJ (1975) The present status of radical prostatectomy for stages A and B prostatic cancer. Urol Clin North Am 2:105–131

    PubMed  CAS  Google Scholar 

  39. Kastendieck H (1977) Ultrastrukturpathologie der menschlichen Prostatadrüse. Cyto- und Histomorphogenese von Atrophie, Hyperplasie, Metaplasie, Dysplasie und Carcinom. (Progress in Pathology 106) Fischer, Stuttgart, pp 1–167

    Google Scholar 

  40. Kastendieck H (1980) Prostatic carcinoma. Aspects of pathology, prognosis and therapy. J Cancer Res Clin Oncol 96:131–156

    Article  PubMed  CAS  Google Scholar 

  41. Kastendieck H (1980) Correlations between atypical primary hyperplasia and carcinoma of the prostate. A histological study of 180 total prostatectomies. Pathol Res Pract 169:366–387

    Article  PubMed  CAS  Google Scholar 

  42. Kastendieck H (1985) Das Mikrokarzinom der Prostata. Helv Chir Acta 52:503–519

    PubMed  CAS  Google Scholar 

  43. Kastendieck H, Altenaehr E (1976) Cyto- and histomorphogenesis of the prostate carcinoma. A comparative light and electron microscopic study. Virchows Arch [A] 370:207–224

    Article  CAS  Google Scholar 

  44. Kastendieck H, Altenaehr E, Huesselmann H, Bressel M (1976) Carcinoma and dysplastic lesions of the prostate. A histomorphological analysis of 50 total prostatectomies by step-section technique. Z Krebsforsch 88:33–54

    Article  CAS  Google Scholar 

  45. Koss L (1988) Panel discussion and questions — prostate cytopathology. In: Karr JP, Coffey DS, Gardner W (eds) Prognostic cytometry and cytopathology of prostate cancer. Elsevier, New York, pp 138–146

    Google Scholar 

  46. Kovi J (1985) Microscopic differential diagnosis of small adenocarcinoma of the prostate. Pathol Annu 20:157–196

    PubMed  Google Scholar 

  47. Kovi J, Jackson MA, Heshmat MY (1985) Ductal spread in prostatic carcinoma. Cancer 56:1566–1573

    Article  PubMed  CAS  Google Scholar 

  48. Kovi J, Mostofi FK, Heshmat MY, Enterline JP (1988) Large acinar atypical hyperplasia and carcinoma of the prostate. Cancer 61:555–561

    Article  PubMed  CAS  Google Scholar 

  49. Layfield LJ, Ritchie AWS, deKernion JB (1988) Fine needle aspiration of the prostate: technique and interpretation. In: Karr JP, Coffey DS, Gardner W (eds) Prognostic cytometry and cytopathology of prostate cancer. Elsevier, New York, pp 19–30

    Google Scholar 

  50. Liavag J (1968) Atrophy and regeneration in pathogenesis of prostatic carcinoma. Acta Pathol Microbiol Scand 73:338–350

    Article  PubMed  CAS  Google Scholar 

  51. Liavag J, Harbitz TB, Haugen OA (1972) Latent carcinoma of the prostate. Recent Results Cancer Res 39:131–137

    PubMed  CAS  Google Scholar 

  52. Linoli O (1986) Studio istologico del carcinoma della prostata in soggetti di eta’ da 51 a 90 anni. Pathologica 78:277–308

    PubMed  CAS  Google Scholar 

  53. McNeal JE (1965) Morphogenesis of prostatic carcinoma. Cancer 18:1659–1665

    Article  PubMed  CAS  Google Scholar 

  54. McNeal JE (1969) Origin and development of carcinoma of the prostate. Cancer 23:24–34

    Article  PubMed  CAS  Google Scholar 

  55. McNeal JE (1972) The prostate and the prostatic urethra: a morphologic synthesis. J Urol 107:1008–1016

    PubMed  CAS  Google Scholar 

  56. McNeal JE (1981) Normal and pathologic anatomy of the prostate. Urology 17:11–16

    PubMed  CAS  Google Scholar 

  57. McNeal JE, Bostwick DG (1986) Intraductal dysplasia: a premalignant lesion of the prostate. Hum Pathol 17:64–71

    Article  PubMed  CAS  Google Scholar 

  58. McNeal JE, Bostwick DG, Kindrachuk RA, Redwine EA, Freiha FS, Stamey TA (1986) Patterns of progression in prostate cancer. Lancet 1:60–63

    Article  PubMed  CAS  Google Scholar 

  59. Melicow MM (1966) Cancer of the prostate: concepts and guide lines in histological diagnosis. J Urol 95:791–800

    PubMed  CAS  Google Scholar 

  60. Mellinger GT, Gleason DF, Bailar J III (1967) The histology and prognosis of prostatic cancer. J Urol 97:331–337

    PubMed  CAS  Google Scholar 

  61. Miller GJ (1988) An atlas of prostatic biopsies: dilemmas of morphologic variance. Prog Surg Pathol 8:81–112

    Google Scholar 

  62. Miller GJ (1988) Panel discussion and questions. Prostate cytopathology. In: Karr JP, Coffey DS, Gardner W Jr (eds) Prognostic cytometry and cytopatholgy of prostate cancer. Elsevier, New York, pp 138–146

    Google Scholar 

  63. Miller A, Seljelid R (1971) Cellular atypia in the prostate. Scand J Urol Nephrol 5:17–21

    Article  PubMed  CAS  Google Scholar 

  64. Miller GJ, Shikes JL (1988) Nuclear roundness as a predictor of response to hormonal therapy of patients with stage D2 prostatic cancer. In: Karr JP, Coffey DS, Gardner W Jr (eds) Prognostic cytometry and cytopathology of prostate cancer. Elsevier, New York, pp 349–353

    Google Scholar 

  65. Moore RA (1935) The morphology of small prostatic carcinoma. J Urol 33:224–234

    Google Scholar 

  66. Mostofi FK, Sesterhenn IA, Davis CJ (1987) Progress in pathology of carcinoma of prostate. In: Prostate cancer, part A: Research, endocrine treatment, and histopathology. Liss, New York, pp 445–475

    Google Scholar 

  67. Murphy WM, Gaeta JF (1989) Diseases of prostate gland and seminal vesicles. In: Murphy WM (ed) Urological pathology. Saunders, Philadelphia

    Google Scholar 

  68. Russo J (1983) Basis of cellular autonomy in the susceptibility to carcinogenesis. Toxicol Pathol 12:149–166

    Article  Google Scholar 

  69. Russo J, Russo IH (1987) Biology of the disease. Biological and molecular bases of mammary carcinogenesis. Lab Invest 57:112–137

    PubMed  CAS  Google Scholar 

  70. Srigley JR (1988) Small-acinar patterns in the prostate gland with emphasis on atypical adenomatous hyperplasia and small-acinar carcinoma. Semin Diagn Pathol 5:254–272

    PubMed  CAS  Google Scholar 

  71. Tannenbaum M (1975) Differential diagnosis in uropathology: carcinoma in situ of prostate gland. Urology 5:143–146

    Article  PubMed  CAS  Google Scholar 

  72. Tannenbaum M (1977) Histopathology of prostate gland. In: Tannenbaum M (ed) Urologic pathology: the prostate. Lea and Febiger, Philadelphia, pp 303–397

    Google Scholar 

  73. Tannenbaum M, Droller KJ (1987) Primary atypical epithelial hyperplasia of prostate gland: a premalignant lesion? World J Urol 5:92–95

    Article  Google Scholar 

  74. Troncoso P, Ro J, Grignon D, von Eschenbach A, Ayala A (1988) Prostatic intraepithelial neoplasia and invasive prostatic adenocarcinoma in cystoprostatectomy specimens. Lab Invest 58:95A

    Google Scholar 

  75. Wernert N, Dhom G (1984) Morphologie und Differentialdiagnose der cribriformen Prostatahyperplasien. Pathologe 5:27–32

    PubMed  CAS  Google Scholar 

  76. Whitmore WF (1956) Hormon therapy in prostatic cancer. Am J Med 21:697–713

    Article  PubMed  Google Scholar 

  77. Young RH (1988) Pseudoneoplastic lesions of the prostate gland. Pathol Annu 23:105–128

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Istituto di Anatomia e Istologia Patologica, Università degli Studi di Genova, Via A. de Toni 14, I-16132, Genova, Italy

    S. Battaglia

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  1. S. Battaglia
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Editors and Affiliations

  1. Urologische Abteilung, Krankenhaus der Barmherzigen Brüder, Romanstraße 95, W-8000, München 19, Germany

    Jens E. Altwein  & Wolfgang Schneider  & 

  2. Urologische Abteilung, Stadtkrankenhaus Memmingen, W-8940, Memmingen, Germany

    Peter Faul

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© 1991 Springer-Verlag Berlin Heidelberg

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Battaglia, S. (1991). Histogenesis of Incidental Carcinoma of the Prostate. In: Altwein, J.E., Faul, P., Schneider, W. (eds) Incidental Carcinoma of the Prostate. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76129-4_10

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  • DOI: https://doi.org/10.1007/978-3-642-76129-4_10

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  • Print ISBN: 978-3-642-76131-7

  • Online ISBN: 978-3-642-76129-4

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