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The Influence of Selected Antimicrobial and Antineoplastic Drugs on Chemiluminescence of Peripheral Granulocytes

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Book cover Immunotherapeutic Prospects of Infectious Diseases

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Abstract

Antibacterial oxidative killing mechanisms (“respiratory burst”) of peripheral granulocytes are of great importance in patients with a high risk of infection (von Dyke et al. 1979, Gillissen, 1980, Mandell, 1982, Duncker and Ullmann, 1986, Geisen et al., 1986). Factors negatively influencing these defensive mechanisms are risk factors to the patient.

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References

  • Duncker, D., Ullmann, U. (1986) Influence of various antimicrobial agents on the chemiluminescence of phagocytosing human granulocytes. Chemotherapy, Basel 32: 18–24

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  • Van Dyke, K., van Dyke, C., Udeinya, J., Brister, C., Wilson, M. (1979) A new screening system for nonsteroídal anti-inflammatory drugs based upon inhibition of chemiluminescence produced from human cells (granulocytes). Chlin. chem.- New York 25: 1655–1661

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  • Geisen, H.P., Schipplick, M., Schömig-Breckner, J., Betzler, M. (1986) Granulozytenfunktion unter dem Einfluß von Antibiotika. Beitr. Infusionstherapie klin. Ernähr. - Basel 15: 277–284

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  • Gillissen, G. (1980) Antibiotika und Immunantwort–Begleiteffekte der Chemotherapie. Immunität und Infektion 8: 79–88

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  • Mandell, L.A. (1982) Effects of antimicrobial and antineoplastic drugs on the polymorphonuclear leukocyte. Rev. inf. diseases 4: 683–695

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Author information

Authors and Affiliations

  1. Institute of Immunology of the Military Medical Academy, 1242, Bad Saarow, GDR

    B. Wulf

  2. Institute of Internal Clinic of the Military Medical Academy, 1242, Bad Saarow, GDR

    H. Koch

Authors
  1. B. Wulf
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  2. H. Koch
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Editor information

Editors and Affiliations

  1. Robert-Koch-Institut, Bundesgesundheitsamtes, Nordufer 20, 1000, Berlin 65, Germany

    K. Noel Masihi  & Werner Lange  & 

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© 1990 Springer-Verlag Berlin Heidelberg

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Wulf, B., Koch, H. (1990). The Influence of Selected Antimicrobial and Antineoplastic Drugs on Chemiluminescence of Peripheral Granulocytes. In: Masihi, K.N., Lange, W. (eds) Immunotherapeutic Prospects of Infectious Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76120-1_29

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  • DOI: https://doi.org/10.1007/978-3-642-76120-1_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76122-5

  • Online ISBN: 978-3-642-76120-1

  • eBook Packages: Springer Book Archive

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