Some Novel Pharmacological Properties of Lentinan

  • K. Mašek
  • H. Mostecká
  • J. Seifert
  • H. Farghali
  • G. Chihara
  • Y. Kaneko
Conference paper

Abstract

Lentinan (LTN), a natural polysaccharide isolated from the mushroom Lentinus edodes, is known to have a number of biological activities. Lentinan augments the host resistance to bacterial and viral infections and shows an antitumor activity (Suga et al. 1986). No exact mechanism of its activity is known, it is, however, suspected that the compound augments the reactivity of immunocompetent cells to major lymphokines and possibly also to some hormones and neurotransmitters. Lentinan has been reported also to increase markedly the synthesis of several protein components (Suga et al. 1986).

Keywords

Toxicity Lactate Polysaccharide Alanine Cyclophosphamide 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • K. Mašek
    • 1
  • H. Mostecká
    • 1
  • J. Seifert
    • 1
  • H. Farghali
    • 1
  • G. Chihara
    • 2
  • Y. Kaneko
    • 2
  1. 1.Institute of PharmacologyCzechoslovak Academy of SciencesPragueCzechoslovakia
  2. 2.Ajinomoto CompanyTokyoJapan

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