Abstract
Most allergy models are based on immunological studies on so-called “inert” antigens such as pollen grains, house mite feces or food proteins. In the IgE-immediatetype allergy to pollen, the reaction mechanism can be represented by a model in which mucosal mast cells are triggered by specific IgE-bearing receptors after activation by both surface and cytoplasmic antigens that are instantly released by the pollen grain upon landing on the nasal or respiratory mucosa. In the case of living fungal cells, the exact sequence in which antigens/allergens are exposed to the immune system upon contact with the mucosa are not known for the majority of air- or food-borne fungi.
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Gumowski, P.I., Dunoyer-Geindre, S., Latgé, J.P. (1991). Candida Cell Wall Antigens Inducing Allergic Symptoms. In: Latgé, J.P., Boucias, D. (eds) Fungal Cell Wall and Immune Response. NATO ASI Series, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76074-7_29
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DOI: https://doi.org/10.1007/978-3-642-76074-7_29
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