Chronic Myelomonocytic Leukemia with Lymphadenopathy
Localized or, more often, generalized enlargement of lymph nodes is a possible, yet uncommon, occurrence in chronic myelomonocytic leukemia. It seems to be more frequent in children [5, 14, 17] than in adults. However the interpretation of lymph node biopsies in such cases may be confusing and may even lead to misdiagnosis . For this reason we decided with the Rennes (J. Goasguen), Nantes (R. Garand), Angers (J. L. Bremond), and Tours (J. Gardais) units of the Groupe Française de Morphologie Hematologique to examine cases of myelodysplastic syndromes, concentrating on the cases of chronic myelomonocytic leukemia which were reported as being associated with lymphadenopathy. In cases in which a biopsy had been performed we reviewed the slides of these.
KeywordsAcute Myeloid Leukemia Myelodysplastic Syndrome Granulocytic Sarcoma Chronic Myelomonocytic Leukemia Nodal Architecture
Unable to display preview. Download preview PDF.
- 4.Briere J, Dresch C, Briere JF, Faille A (1977) Leucémies myelomonocytaires subaigües ou chroniques de l’adulte. Actual Hematol 11: 53–80Google Scholar
- 7.Duguid JKM, Mackie MJ, McVerry (1983) Skin infiltration associated with chronic myelomonocytic leukaemia. Br J Haematol 53: 257–264Google Scholar
- 8.Editorial (1973) Chloroma confusion. Lancet 1: 1099–2000Google Scholar
- 17.Vela-Ferrer E, BaIlesta-Martinez F, Molina-Font JA, Cruz-Hernandez M (1976) Leucosis mielomonocitica en el nino. An Esp Pediatr 4: 12–17Google Scholar