Skip to main content

Risikofaktoren beim malignen Melanom

  • Conference paper
Das Maligne Melanom
  • 40 Accesses

Zusammenfassung

Sofern das Melanom in einem frühen Wachsstumsstadium erkannt wird, kann es in den meisten Fällen durch einfache chirurgische Behandlung geheilt werden. Der Verdacht auf ein Melanom sollte sich zuerst aufgrund der Anamnese ergeben, sodann aus dem klinischen Bild, wobei erfahrene Dermatologen in über 95% der Fälle bereits eine Diagnose stellen können. Der Arzt muß daher mit den charakteristischen Merkmalen des Hautmelanoms sehr gut vertraut sein, so daß bei verdächtigen Pigmentmalen zum frühestmöglichen Zeitpunkt eine histologische Untersuchung erfolgen kann. Neben dem spontan auftretenden Melanom, gibt es Bevölkerungsgruppen, die ein erhöhtes Risiko auf die Inzidenz eines Melanoms haben. Diese Personen müssen im Rahmen eines Screening-Programmes automatisch regelmäßig auf Vorläuferläsionen bzw. auf spontanes Auftreten eines malignen Melanoms untersucht werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Ances IG, Pomerantz SH (1974) Serum concentrations of ß melanocyte-astimulating hormone in human pregnancy. Am J Obstet Gynecol 119: 1062–1068

    PubMed  CAS  Google Scholar 

  2. Austin DF, Reynolds P (1986) Occupation and malignant melanoma of the skin. In: Gallagher RP (ed) Epidemiology of Malignant Melanoma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  3. Bain C, Hennekens C, Speizer FC et al (1982) Oral contraceptive use and malignant melanoma. JNCI 68: 537–539

    PubMed  CAS  Google Scholar 

  4. Bale SJ, Dracopoli NC, Tucker MA, Clark WH jr, Fraser MC, Stanger BZ, Green P, Donis-Keller H, Housman DE, Greene MH (1989) Mapping the Gene for Hereditary cutaneous malignant Melanoma-Dysplastic Nevus to Chromosome 1p. N Engl J Med 320: 1367–1372

    Article  PubMed  CAS  Google Scholar 

  5. Clark WH, Mastrangelo MJ, Ainsworth AM, Berd D, Bellet RE, Bernardino EA (1977) Current concepts of the biology of human cutaneous malignant melanoma. Adv Cancer Res 24: 267–338

    Article  PubMed  Google Scholar 

  6. Cooke KR, Skeegg DCG, Fraser J (1984) Socio-economic status, indoor and outdoor work, and malignant melanoma. Int J Cancer 34: 57–62

    Article  PubMed  CAS  Google Scholar 

  7. Elder DE, Goldman LI, Goldman SC et al (1980) Dysplastic nevus syndrome: a phenotypic association of sporadic cutaneous melanoma. Cancer 46: 1787–1794

    Article  PubMed  CAS  Google Scholar 

  8. Elder DE, Kraemer KH, Greene MH, Clark WH, Guerry D (1982) The dysplastic nevus syndrome: our definition. Am J Dermatopath 4: 455–460

    Article  PubMed  CAS  Google Scholar 

  9. Elwood JM, Coldman AJ (1987) Previous pregnancy and melanoma prognosis. Lancet 11: 1000–1001

    Google Scholar 

  10. Fisher MS, Kripke ML (1982) Suppressor T-lymphocytes control the development of primary skin cancers in ultraviolet irradiated mice. Science 216: 1133–1134

    Article  PubMed  CAS  Google Scholar 

  11. Gallagher RP, Elwood JM, Hill GB (1986) Risk factors for cutaneous malignant Melanoma. The Western Canada Melanoma Study. In: Gallagher RP (ed) Epidemiology of Malignant Melanoma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  12. Green MH, Fraumen JF (1979) The hereditary variant of malignant melanoma. In: Clark WH jr, Goldman LI, Mastrangelo MJ (eds) Human malignant melanoma. Grune & Stratton, New York, pp 139–166

    Google Scholar 

  13. Green MH, Goldin R, Clark WH et al (1983) Familial cutaneous malign melanoma: Autosomal dominant trail possibly linked to the Rh locus. Proc Natl Acad Sci USA 80: 6071–6075

    Article  Google Scholar 

  14. Green A, Mac Lennan R, Siskind V (1985) Common acquired naevi and the risk of malignant melanoma. Int J Cancer 35: 297–300

    Article  PubMed  CAS  Google Scholar 

  15. Green A, Siskind V, Bain C, Alexander J (1985) Sunburn and malignant melanoma. Br J Cancer 51: 393–397

    Article  PubMed  CAS  Google Scholar 

  16. Green A, Bain C, McLennan R, Siskind V (1986) Risk factors for cutaneous Melanoma in Queensland. In: Gallagher RP (ed) Epidemiology of Malignant Melanoma. Springer, Berlin Heidelberg New York Tokyo, pp 76–97

    Google Scholar 

  17. Green A, Bain C (1985) Hormonal factors and melanoma in women. Med J Aust 142: 446–448

    PubMed  CAS  Google Scholar 

  18. Green A (1984) Sun exposure and the risk of melanoma. Aust J Dermatol 25: 99–102

    Article  CAS  Google Scholar 

  19. Holly EA, Weiss NS, Liff J (1983) Cutaneous malignant melanoma in relation to exogenous hormones and reproductive factors. JNCI 70: 827–831

    PubMed  CAS  Google Scholar 

  20. Holly EA (1986) Melanoma and Pregnancy. In Gallagher RP (ed) Epidemiology of Malignant Melanoma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  21. Holley EA (1986) Cutaneous Melanoma and Oral Contraceptives: A review of case-control and cohort studies. In: Gallagher RP (ed.) Epidemiology of Malignant Melanoma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  22. Holman CD J, James IR, Gattey PH et al (1980) An analysis of trends in mortality from malignant melanoma of the skin in Australia. Int J Canc 26: 703–709

    Article  CAS  Google Scholar 

  23. Holman CDJ, Armstrong BK, Heenan PJ (1983) A theory of the etiology and pathogenesis of human cutaneous malignant melanoma. JNCI 71: 651–656

    PubMed  CAS  Google Scholar 

  24. Houghton AN, Flannery J, Viola MV (1981) Malignant melanoma of the skin occurring during pregnancy. Cancer 48: 407–410

    Article  PubMed  CAS  Google Scholar 

  25. Kokoschka EM, Luger Th, Schmidt J, Spona J, Bieglmayer Ch (1981) Steroidrezeptoranalyse an malignen Melanomen. Hautarzt [Suppl V] 32: 70–72

    Google Scholar 

  26. Lee JAH, Strickland D (1980) Malignant melanoma: social status and outdoor work. Br J Cancer 41: 757–763

    Article  PubMed  CAS  Google Scholar 

  27. Lopez RE, Bhakoo, Paolini NS, Rosen F, Holyhoke ED, Godrosen MH (1978) Effect of estrogen in the growth of B-16 melanoma. Surg Forum 29: 153–154

    PubMed  CAS  Google Scholar 

  28. Lynch HT, Frichot BC III, Lynch JF (1978) Familial atypical multiple mole-melanoma syndrome. J Med Genet 15: 352

    Article  PubMed  CAS  Google Scholar 

  29. MacKie RM, Aitchison T (1982) Severe sunburn and subsequent risk of primary cutaneous melanoma in Scotland. Br J Cancer 46: 955–960

    Article  PubMed  CAS  Google Scholar 

  30. McGovern VJ (1977) Epidemiological aspects of melanoma: a review. Pathology 9: 233–241

    Article  PubMed  CAS  Google Scholar 

  31. Milton GW, Balch CM, Shaw HM (1988) Klinik (Symptomatologie, klinische Diagnose und Differentialdiagnose) In Balch CM, Milton GW et al (eds.) Hautmelanoma. Diagnose, Therapie und weltweite Ergebnisse. Springer, Berlin Heidelberg New York Tokyo, S 13–31

    Google Scholar 

  32. Neifeld JP, Lippman ME (1980) Steroid hormone receptors and melanoma. J Invest Derm 74: 379–381

    Article  PubMed  CAS  Google Scholar 

  33. Niebauer G, Kokoschka EM (1986) Das dysplastische Nävussyndrom. Wien Klin Wochenschr 98 (20): 673–678

    PubMed  CAS  Google Scholar 

  34. Reynolds P, Austin DF (1984) Epidemiologic-based screening strategies for malignant melanoma of the skin. In: Engstrom PF, Anderson PN, Mortenson LE (eds) Advances in cancer control: epidemiology and research. Liss, New York, pp 245–254

    Google Scholar 

  35. Rosdahl IK (1979) Local and systemic effects on the epidermal melanocyte population in UV-irradiated mouse skin. J Invest Dermatol 70: 143–148

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Kokoschka, EM. (1991). Risikofaktoren beim malignen Melanom. In: Das Maligne Melanom. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75951-2_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-75951-2_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52965-1

  • Online ISBN: 978-3-642-75951-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics