Abstract
Deregulated expression of c-myc secondary to chromosomal alterations is a constant feature of mouse plasmacytomas, rat immunocytomas and human Burkitt lymphomas (Mushinski, 1988). One feature of deregulated expression of c-myc is that all plasmacytomas have high levels of c-myc transcripts, no matter whether their chromosome 15 was interrupted by a rcpt(12;15) translocation, by a rcpt(6;15) translocation, or by interstitial deletion within chromosome 15.
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© 1990 Springer-Verlag Berlin Heidelberg
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Mushinski, J.F., Skurla, R.M., Goodnight, J., Siwarski, D., Huppi, K. (1990). Expression of c-myc and Pvt1. In: Potter, M., Melchers, F. (eds) Mechanisms in B-Cell Neoplasia 1990. Current Topics in Microbiology and Immunology, vol 166. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75889-8_30
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DOI: https://doi.org/10.1007/978-3-642-75889-8_30
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