Abstract
Oscar Wilde might have been referring to the endothelins, since on the one hand they have the potential for causing or exacerbating systemic hypertension, renal artery stenosis, coronary artery occlusion, cerebral vasospasm, and atherosclerosis whilst on the other they inhibit platelet aggregation (Thiemermann et al. 1990) and can be fibrinolytic (Korbut et al. 1989). Except under conditions of severe trauma, when excessive blood loss might be a problem, the ability of these polypeptides to slow platelet aggregation and to activate the fibrinolytic system, must surely be regarded as desirable.
“I hope you are not leading a double life, pretending to be wicked and being really good all the time”.
The Importance of Being Earnest — Oscar Wilde
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© 1990 Springer-Verlag Berlin Heidelberg
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Nayler, W.G. (1990). The Endothelins and Platelet Aggregation. In: The Endothelins. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75872-0_18
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DOI: https://doi.org/10.1007/978-3-642-75872-0_18
Publisher Name: Springer, Berlin, Heidelberg
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