A New Perspective for Drug Delivery Research

  • R. L. Juliano
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 100)

Abstract

As one of the old warhorses of drug delivery research, probably I am entitled to look backward and to take some satisfaction from the enormous progress which has been made since the time, some 15 years ago, when I first became involved with this field. Many things which were merely ephemeral dreams or vague concepts at that point have advanced to clinical application and commercial success. On the other hand, especially in the realm of targeted delivery, many of the problems anticipated in the 1970s remain unsolved. The goal of radically improving the cellular specificity of a drug (and consequently its therapeutic index) through targeted delivery persists as the unrealized Holy Grail of drug delivery research. We move incrementally toward the goal of specific targeting, but formidable chemical and biological barriers remain. However, new hope for specific targeting comes with fundamental new insights into how cells work, and with the technological mastery provided by molecular biology.

Keywords

Europe Platinum Leukemia Oncol Polypeptide 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • R. L. Juliano

There are no affiliations available

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