As indicated in the first chapter of this book, for the origins of research in peptide chemistry one has to look back into the nineteenth century. At that time, with notable exceptions, such as the fundamental work of Jac. Berzelius (1779–1848), who lived and worked in Sweden, most of the important contributions came from France and from Germany. In the first half of this century the leading roles in peptide research were played mainly by German chemists, but during the Second World War this situation underwent a dramatic change. The spectacular progress of biochemistry stimulated worldwide interest in the field and many new investigators, trained as organic chemists, joined the biochemists and thus a new discipline, bio-organic chemistry, developed with peptide chemistry as one of its most productive branches.
KeywordsAngiotensin Disulfide Alkaloid Thrombin Glucagon
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