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Histamine H2 Receptors and Lung Function

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Book cover Histamine and Histamine Antagonists

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 97))

Abstract

The lung is a complex tissue comprising many different cellular elements, including smooth muscle, both airway and vascular; vascular endothelium; respiratory epithelium; mucus-secreting cells; nerves; and connective tissue cells. The purpose of this review is to examine the evidence that histamine H2 receptors which may be present on these cells making up lung tissue have a potential to modify lung function. One of the major difficulties with such a review is the variety of different models that have been used to study histamine-mediated effects in the lung. Furthermore, it will become apparent that there are very great interspecies differences in the actions of histamine on lung tissue.

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  1. J. C. Foreman
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Editors and Affiliations

  1. Department of Pharmacology, Karolinska Institutet, Box 60400, S-104 01, Stockholm, Sweden

    Börje Uvnäs M.D.

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© 1991 Springer-Verlag Berlin Heidelberg

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Foreman, J.C. (1991). Histamine H2 Receptors and Lung Function. In: Uvnäs, B. (eds) Histamine and Histamine Antagonists. Handbook of Experimental Pharmacology, vol 97. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75840-9_17

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  • DOI: https://doi.org/10.1007/978-3-642-75840-9_17

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