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Neurotransmitter Receptors and Voltage-Operated Channels Expressed by Rat Spinal Cord mRNA in Xenopus Oocytes

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Spinal Cord Monitoring and Electrodiagnosis
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Abstract

Spinal cord function involves complex interactions between spinal neurons, segmental input from primary afferent fibers, and suprasegmental input from descending pathways. Various neurotransmitters are thought to be involved in spinal cord function, and many studies have shown that the distribution of neurotransmitters in the spinal cord differs from that in other parts of the central nervous system. Perhaps there is also a difference in the types and densities of the neurotransmitter receptors; but in this respect, only limited information is available, and it derives mainly from receptor binding studies with radiolabeled ligands. Here we describe an alternative approach, using oocytes of the South African clawed frog, Xenopus laevis [9, 10].

This work was supported by grant R01-NS23284 from the U.S. public Health Service

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© 1991 Springer-Verlag Berlin Heidelberg

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Akagi, H., Miledi, R. (1991). Neurotransmitter Receptors and Voltage-Operated Channels Expressed by Rat Spinal Cord mRNA in Xenopus Oocytes. In: Shimoji, K., Kurokawa, T., Tamaki, T., Willis, W.D. (eds) Spinal Cord Monitoring and Electrodiagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75744-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-75744-0_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75746-4

  • Online ISBN: 978-3-642-75744-0

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