Advertisement

The Use of Long-Term Culture Techniques to Study Peripheral Blood Stem Cells Before and After Autologous Transplantation

  • A. Rice
  • C. Foures
  • P. Bernard
  • G. Marit
  • P. Cony-Makhoul
  • E. Bascans
  • F. Lacombe
  • J. Reiffers

Abstract

Autologous blood stem cells collected during the recovery phase after intensive chemotherapy are rich in progenitor cells, and, when infused into patients who have received myeloablative therapy, lead to rapid and durable hematopoietic reconstitution [6]. The rate of engraftment has been demonstrated to be correlated with the number of late progenitor cells infused [4].

Keywords

Acute Lymphocytic Leukemia Nucleate Cell Blood Stem Cell Peripheral Blood Stem Cell Bone Marrow Microenvironment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Dexter TM, Allen TD, Lajtha LG (1977) Conditions controlling the proliferation of hematopoietic stem cells in vitro. J Cell Physiol 91: 335–344PubMedCrossRefGoogle Scholar
  2. 2.
    Gartner S, Kaplan H (1980) Long-term culture of human bone marrow cells. Proc Natl Acad Sci USA 77: 4759–4761CrossRefGoogle Scholar
  3. 3.
    Pike BL, Robinson WA (1970) Human bone marrow colony growth in agar gel. J Cell Physiol 76: 77–84PubMedCrossRefGoogle Scholar
  4. 4.
    Reiffers J, Castaigne S, Tilly H, Lepage E, Leverger G, Douay L (1987) Hematopoietic reconstitution after autologous blood stem cell transplantation: a report of 46 cases. Plasma Ther Transfus Technol 8: 360–362CrossRefGoogle Scholar
  5. 5.
    Reiffers J, Vezon G, Bernard PH, Sarrat A, Marit G, David B, Broustet A (1986) Collection of circulating granulocyte-macrophage precursors in patients with acute nonlymphocytic leukemia. Plasma Ther Transfus Technol 7: 93–96Google Scholar
  6. 6.
    To LB, Haylock DN, Kimber RJ, Juttner CA (1984) High levels of circulating hematopoietic stem cells in very early remission from acute non-lymphoblastic leukaemia. Br J Hematol 58: 399–410CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • A. Rice
    • 1
  • C. Foures
    • 2
  • P. Bernard
    • 2
  • G. Marit
    • 1
  • P. Cony-Makhoul
    • 1
  • E. Bascans
    • 2
  • F. Lacombe
    • 2
  • J. Reiffers
    • 1
  1. 1.Bone Marrow Transplant UnitCHR Bordeaux, Hôpital Haut-LévèquePessacFrance
  2. 2.Hematology LaboratoryCHR Bordeaux, Hôpital Haut-LévèquePessacFrance

Personalised recommendations