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Recent Advances in the Chemistry of Quinolones

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Recent Progress in the Chemical Synthesis of Antibiotics

Abstract

Nalidixic acid was first introduced in therapy in 1963, about 15 years later a new generation of quinolones with broader spectrum of activity appeared: the fluoroquinolones; since then about 6000 new analogs have been disclosed and about 20 derivatives are marketed or in advanced development.

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Author information

Authors and Affiliations

  1. Bristol-Myers Squibb France, Research Laboratories, BP 62, 77422, Marne la Vallee Cedex 2, France

    Daniel Bouzard

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  1. Daniel Bouzard
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Editors and Affiliations

  1. Institut de Chimie des Substances Naturelles du C.N.R.S., Avenue de la Terrasse, F-91198, Gif-sur-Yvette Cedex, France

    G. Lukacs (Directeur de Recherche C.N.R.S.) (Directeur de Recherche C.N.R.S.)

  2. University of Tokyo, 7-3-1 Hongo, Bunkyo-ku Tokyo 113, Japan

    M. Ohno

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© 1990 Springer-Verlag Berlin Heidelberg

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Bouzard, D. (1990). Recent Advances in the Chemistry of Quinolones. In: Lukacs, G., Ohno, M. (eds) Recent Progress in the Chemical Synthesis of Antibiotics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75617-7_7

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  • DOI: https://doi.org/10.1007/978-3-642-75617-7_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75619-1

  • Online ISBN: 978-3-642-75617-7

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