Picornaviruses pp 155-188 | Cite as

Poliovirus Genetics

  • P. Sarnow
  • S. J. Jacobson
  • L. Najita
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 161)


The goal of genetic studies of animal viruses has been the elucidation of the structure and function of the viral genome. The ultimate aim has been the assignment of functions to individual viral polypeptides in infected host cells and the understanding of genetic processes such as transmission, recombination, and complementation. Necessary tools to accomplish these goals are viral mutants, defective in particular processes, whose lesions can be assigned to particular regions of the viral genome.


Noncoding Region Nonpermissive Temperature Amino Acid Insertion Poliovirus Type Polyadenylic Acid 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • P. Sarnow
    • 1
    • 2
  • S. J. Jacobson
    • 1
    • 2
  • L. Najita
    • 1
    • 2
  1. 1.Department of Biochemistry, Biophysics and GeneticsUniversity of Colorado Health Sciences CenterDenverUSA
  2. 2.Department of Microbiology and ImmunologyUniversity of Colorado Health Sciences CenterDenverUSA

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