Lymph Node Reaction Patterns in Patients with AIDS or AIDS-Related Complex

  • J. Diebold
  • J. Audouin
  • A. Le Tourneau
  • S. Prevot
  • G. Szekeres
Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 84/2)


Like many other viral infections, HIV-induced infection causes modifications in lymphoid tissue and especially in lymph nodes. In the early stages, these modifications are responsible for the development of peripheral adenopathie causing lymphadenopathy syndrome (LAS) or, when there are associated clinical and/or biological signs, AIDS-related complex (ARC) [Abrams et al. 1984; Centers for Disease Control (CDC) 1982a]. In the clinical classification proposed by the CDC in 1986, adenopathies can be present in stages III and IV. During the course of the disease, the adenopathies disappear due to progressive lymphoid depletion. In terminal stages, the lymph nodes are atrophic and difficult to locate even during necropsy.


Human Immunodeficiency Virus Germinal Center Acquire Immune Deficiency Syndrome Acquire Immune Deficiency Syndrome Patient Follicular Hyperplasia 
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© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • J. Diebold
  • J. Audouin
  • A. Le Tourneau
  • S. Prevot
  • G. Szekeres

There are no affiliations available

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