Response of Early Stage B-CLL to Interferon-α:2 Years Experience of a Pilot Study
Chronic lymphocytic leukemia of B cell-type (B-CLL) is looked upon as the most common form of leukemia in the western hemisphere. The prognosis varies from 6 months to 25 years. Cytoreductive therapy is usually restricted to patients with hemopoietic insufficiency or with progressive lymphomas. A major problem in these patients, however, is the complex immunodeficiency involving both humoral and cell-mediated immune responses. Cytotoxic regimen have to be used cautiously in order to avoid further deterioration of the immune defense . Therefore, treatment with interferon (IFN) might be an alternative therapeutic strategy, acting in an antineoplastic way and stimulating the immune system at the same time.
KeywordsChronic Lymphocytic Leukemia Human Leukocyte Antigen Lymphocyte Count Chronic Lymphocytic Leukemia Patient Hairy Cell Leukemia
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