Male Sterility in HLA-B27-Transgenic Mice

  • P. Ivanyi
  • W. Lokhorst
Conference paper


The major interest when producing MHC-transgenic mice (TGM) is in studying the immunocompetence of the transgenic animal. In the case of HLA, the TGM provide the unique possibility to examine -in vivo- the function of the individual HLA molecule(s).


Male Sterility Mouse Genome Insertional Mutation Testis Weight Normal Spermatogenesis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • P. Ivanyi
    • 1
  • W. Lokhorst
    • 1
  1. 1.Central Laboratory of the Netherlands Red Cross Blood Transfusion Service and Laboratory for Experimental and Clinical ImmunologyUniversity of AmsterdamAmsterdamThe Netherlands

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