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Intervention in Risk Factors of Ischemic Heart Disease

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Therapie der koronaren Herzerkrankung

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Abstract

Intervention in risk factors with the goal of preventing coronary heart disease (CHD) cannot be effective, complete and successful without first eliminating hypercholesterolemia. Hypercholesterolemia is the most pivotal and direct cause of atherogenesis in the coronary arteries. The definition of hypercholesterolemia is gradually undergoing changes towards lower levels than previously anticipated. Some 360000 men in the US MRFIT screening program (nonintervention) were followed for 7 years. The results indicate that the incidence of CHD is 30% lower at cholesterol levels of 150 mg/dl than it is at 200 mg/dl, and it doubles at 250 and doubles again at 300 mg/dl. In the absence of mass hypercholesterolemia as in Japan, CHD is a rare cause of disease or death, in spite of continuing high rates of other risk factors such as hypertension, cigarette smoking and diabetes.

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Authors
  1. S. Heyden
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  2. K. A. Schneider
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  3. P. Singer
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Editors and Affiliations

  1. Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum, Lothstr. 11, D-8000, München 2, Deutschland

    W. Rudolph

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© 1990 Springer-Verlag, Berlin Heidelberg New York

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Heyden, S., Schneider, K.A., Singer, P. (1990). Intervention in Risk Factors of Ischemic Heart Disease. In: Rudolph, W. (eds) Therapie der koronaren Herzerkrankung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75318-3_1

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  • DOI: https://doi.org/10.1007/978-3-642-75318-3_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52032-0

  • Online ISBN: 978-3-642-75318-3

  • eBook Packages: Springer Book Archive

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