Abstract
The detection of antibodies specific for Helicobacter (Campylobacter) pylori is gaining importance for the diagnosis of chronic gastritis associated with this pathogen [12,14]. Compared with invasive diagnostic methods or breath tests, serodiagnosis is much easier to perform, cheaper, and, above all, less stressful to the patient. Furthermore, for the purpose of studying the efficacy of therapeutic regimens, it appears well suited for monitoring the colonization of the gastric mucosa with H. pylori (Fig. 1). This is advantageous since in studies such as these frequent endoscopies are necessary over a long period, which is expensive and not a factor conducive to patient compliance. Of course, biopsy speciriens would still be indispensable for cultivation of the pathogen, typing, and sensitivity testing, as well as for histological check-up, but the frequency of taking them could Possibly be significantly reduced.
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Hirschl, A.M., Rotter, M.L. (1990). Serodiagnosis of Helicobacter pylori Infections: Suitability of Various Antigen Preparations. In: Malfertheiner, P., Ditschuneit, H. (eds) Helicobacter pylori, Gastritis and Peptic Ulcer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75315-2_21
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DOI: https://doi.org/10.1007/978-3-642-75315-2_21
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