Abstract
During the last decade two innovations have been introduced in the treatment of aneurysms:
-
1.
Early surgery
-
2.
The administration of nimodipine for the prevention and treatment of vasospasm
However, there is still discussion about several issues: What is the real effect of nimodipine and how significant are the beneficial effects of calcium antagonists in combination with early surgery? On this issue several controlled double-blind studies have been reported with positive results [5,7,8]. In addition to these publications it seems interesting to consider the results in a series of patients treated in clinical routine and not under the ideal circumstances of a controlled study. The treatment results in such a group of patients are reported here, with special reference to postoperative vasospasm.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Auer LM, Brandt L, Ebeling U et al. (1986) Nimodipine and early aneurysm operation in good condition SAH patients. Acta Neurochir (Wien) 82:7–13
Davis JM, Davis KR, Crowell RM (1980) Subarachnoid haemorrhage secondary to ruptured intracranial aneurysm: prognostic significance of cranial CT. AJR 134:711–715
Disney L, Weir B, Petruk K (1987) Effect on management mortality of a deliberate policy of early operation on supratentorial aneurysms. Neurosrugery 20:695–701
Gilsbach JM (1988) Nimodipine in the prevention of ischaemic deficits after aneurysmal subarachnoid hemorrhage. Acta Neurochir (Wien) 45:41–50
Gilsbach JM, Härders AG (1989) Morbidity and mortality after early aneurysm surgery — a prospective study with nimodipine prevention. Acta Neurochir (Wien) 96:1–7
Ljunggren B, Brandt L, Säveland H, Nilsson PE, Cronquist S, Andersson KE, Vinge E (1984) Outcome in 60 consecutive patients treated with early aneurysm operation and intravenous nimodipine. J Neurosurg 61:864–873
Mee E, Dorrance D, Lowe D, Neil-Dwyer G (1988) Controlled study of nimodipine in aneurysm patients: treatment early after subarachnoid hemorrhage. Neurosurgery 22:484–491
Pickard JD, Murray GD, Illing worth R et al. (1989) Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. Br Med J 298:636–642
Sano K (1985) Timing of surgery, operative mortality, and follow-up results in cases with subarachnoid hemorrhage due to aneurysm rupture. In: Auer LM (ed) Timing of aneurysm surgery, de Gruyter, Berlin, pp 227–236
Solomon RA, Post KD, McMurtry JG in (1984) Depression of circulating blood volume in patients after subarachnoid hemorrhage: implications for the management of symptomatic vasospasm. Neurosurgery 15:354–361
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Brawanski, A., Ullrich, W., Holzschuh, M., Meixensberger, J. (1990). Experience with Deliberate Early Aneurysm Surgery and Nimodipine. In: Bushe, KA., Brock, M., Klinger, M. (eds) Stabilizing Craniocervical Operations Calcium Antagonists in SAH Current Legal Issues. Advances in Neurosurgery, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75283-4_36
Download citation
DOI: https://doi.org/10.1007/978-3-642-75283-4_36
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-51967-6
Online ISBN: 978-3-642-75283-4
eBook Packages: Springer Book Archive