Abstract
Experiments by Arroyo et al. (1986) with neutrons indicate that radical yields in oriented DNA at 77 K are both qualitatively and quantitatively different when the secondary proton flux traverses the sample in a direction that is approximately parallel to the orientation of DNA molecules. These findings suggest that energy and/or charge transfer influences the production and/or decay of free radicals when multiple excitations are produced in the same DNA chain. Singlet and triplet excitons can migrate along DNA for a few nanometers before they are trapped, but this type of energy transfer should be equally effective in coupling events within the small clusters of excitation (spurs) that are present in both irradiation geometries.
Work supported by the Office of Health and Environmental Research (OHER), U. S. Department of Energy under contract DE-AC06-76RL0 1830.
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References
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© 1991 Springer-Verlag Berlin Heidelberg
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Miller, J.H. (1991). Role of Energy and Charge Transfer in DNA Damage by Densely Ionizing Radiation. In: Fielden, E.M., O’Neill, P. (eds) The Early Effects of Radiation on DNA. NATO ASI Series, vol 54. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75148-6_16
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DOI: https://doi.org/10.1007/978-3-642-75148-6_16
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